Effect of histamine h 1 receptors on secretory function and blood flow in gastric mucosa
Beregovaya, T.V.; Khomenko, T.A.; Gukin, V.A.
Farmakologiya i Toksikologiya 53(1): 41-43
In chronic experiments on dogs with the gastric fistulas it was shown that H1-histamine blockers (suprastin, peritol, pipolphen) fail to enhance histamine secretion and a selective H1-agonist IEM-813 fails to suppress it. It was also found that the ability of pipolphen to suppress the gastric secretion was due to its cholinolytic properties.