EurekaMag.com logo
+ Site Statistics
References:
53,517,315
Abstracts:
29,339,501
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Effect of noradrenaline on current clamped and voltage clamped muscle cells of the guinea pig vas deferens in normal krebs solution



Effect of noradrenaline on current clamped and voltage clamped muscle cells of the guinea pig vas deferens in normal krebs solution



European Journal of Pharmacology 163(1): 181-186



The ionic mechanism underlying the time-dependent alteration in the action potential configuration by noradrenaline (NA) was studied using vas deferens muscle vlotage-clmaped according to the double sucrose gap method. Early exposure to NA enhanced the inward Ca2+ current (ca) by increasing conductance whereas late exposure diminished Ica by reducing the driving force. The degree of increase in the peak outward K+ curent (IK') was higher with a greater enhancement of Ica by NA but the late outward K+ current (IK) was insensitive to NA.

(PDF 0-2 workdays service: $29.90)

Accession: 007254833

Download citation: RISBibTeXText



Related references

Effect of noradrenaline on current- and voltage-clamped muscle cells of the guinea-pig vas deferens in normal Krebs solution. European Journal of Pharmacology 163(1): 181-185, 1989

The effects of nonhydrolyzable analogue of atp on current clamped and voltage clamped muscle cells of the guinea pig vas deferens. Japanese Journal of Physiology 40(SUPPL): S257, 1990

Voltage fluctuations in clamped or current clamped excitable cells. Biophysical Journal 47(2 PART 2): 64A, 1985

The voltage dependent blocking effect of phalloidin on the delayed potassium current of voltage clamped frog skeletal muscle fibers. European Journal of Pharmacology 120(2): 209-216, 1986

Measurement of whole-cell calcium current in voltage-clamped vascular muscle cells. Molecular and Cellular Biochemistry 80(1-2): 87-93, 1988

Ca2+-dependent K+ current and exocytosis in responses to caffeine and muscarine in voltage-clamped guinea-pig adrenal chromaffin cells. Journal of Neurochemistry 78(6): 1243-1255, September, 2001

Antamanide antagonizes the phalloidin-induced negative inotropic effect and blocks voltage dependently the fast outward K+ current in voltage-clamped frog muscle fibres. European Journal of Pharmacology 138(1): 21-27, 1987

Antamanide antagonizes the phalloidin induced negative inotropic effect and blocks voltage dependently the fast outward potassium current in voltage clamped frog muscle fibers. European Journal of Pharmacology 138(1): 21-28, 1987

Possible effects of calcium entry at positive potentials on contraction in voltage clamped cells isolated from guinea pig ventricular muscle. Journal of Physiology (Cambridge) 396: 81P, 1988

Electroporation-induced inward current in voltage-clamped guinea pig ventricular myocytes. Journal of Membrane Biology 238(1-3): 69-80, 2011

The depressing effect of tetracaine and ryanodine on the slow outward current correlated with that of contraction in voltage clamped frog muscle fibers. Pfluegers Archiv European Journal of Physiology 416(1-2): 106-112, 1990

Persistent slow inward calcium current in voltage-clamped hippocampal neurones of the guinea-pig. Journal of Physiology 337: 303-320, 1983