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Effect of sheath on in vitro melanization of microfilariae of brugia malayi and brugia pahangi



Effect of sheath on in vitro melanization of microfilariae of brugia malayi and brugia pahangi



Japanese Journal of Parasitology 40(4): 358-362



In in vitro melanization of microfilariae (Mf) of Brugia spp. using pupal haemolymph of mosquitoes, Armigeres subalbatus, Mf of Brugia malayi with sheath are less melanized than those of B. pahangi. After artifical exsheathment of Mf, B. malayi showed strong melanization, while B. pahangi showed a very weak reaction. These results entirely agree with the data of melanizing responses in experimental infection of Ar. subalbatus with B. malayi and B. pahangi. Surface properties of cuticles of Mf from both filarial species seem to be important in eliciting the melanization responses of Ar. subalbatus.

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Accession: 007259494

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