Effects of bethanechol and adreno blockers on thermoregulation in spinal cord injury

Berard, E.J.J.; Boucand, M.H.; Depassio, J.; Fyon, J.P.

Paraplegia 27(1): 46-50


ISSN/ISBN: 0031-1758
Accession: 007269354

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The authors report two cases of hypothermia due to a treatment associating Bethanechol and Adreno-Blockers. They emphasize the mechanisms of thermoregulation and discuss the pathophysiology of such hypothermia incidents. The most evident explanation is heat loss, principally mediated through Bethanechol, whereas mechanisms of heat preservation are prevented by Adreno-Blockers. Patients susceptible to this risk must be carefully monitored.