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Effects of selection in mice 2. direct response in 6 week body weight and correlated changes in 6 week tail length and litter size at birth



Effects of selection in mice 2. direct response in 6 week body weight and correlated changes in 6 week tail length and litter size at birth



Indian Journal of Animal Sciences 59(9): 1128-1138



The direct response in 6-week body weight and correlated changes in 6-week tail length and litter size at birth of Swiss Albino mice was studied sex-wise with the help of a contemporaneous unselected control population for 7 generations. The intensity of selection was much higher for males than for females in most of the generations. The inbreeding coefficient was higher in the selected line than in control in each generation. F3, F4 and F5 males of the selected line were heavier than that of the 0 generation by 3.05, 1.97 and 2.40 g respectively. In the control the F3, F4 and F5 males were heavier than the 0 generation only by 1.54, 0.36 and 1.14 g respectively. Marked reduction in weight was noticed in F6 and F7 in both the selected and control lines. The females showed lesser response than males. In the A line both 6-week tail length and litter size at birth showed concomitant changes in most of the generations. The control line showed associated changes in tail length in all the 7 generations. This pattern was also seen for litter size at birth in most of the generations. Pleiotropy could be the primary cause of the correlated responses of both the traits rather than the transient effects of linkage.

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Accession: 007284174

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