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Gaucher's disease;thirty-two years experience at Siriraj Hospital
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Endoscopic resection of esophageal tumor following local injection of hypertonic saline epinephrine


Endoscopic resection of esophageal tumor following local injection of hypertonic saline epinephrine



Gastroenterological Endoscopy 32(12): 2938-2946



An endoscopic resection method, which we developed for resection of early gastric cancer with local injection of hypertonic saline-epinephrine (HSE) solution, was applied to 7 cases of esophageal tumor. The way of endoscopic resection with local injection of HSE solution (ERHSE) is summarized as follows. 1. Marking on mucous membrane to incise by scalpel (needle type). 2. Local injection of HSE solution by needle for endoscopy. 3. Incision of marked mucous membrane by scalpel. 4. Somewhat mobilization of the lesion with forceps. 5. Squeeze and resection with high frequency current snare. In this way, all of 7 cases were completely resected and diagnosed pathologically. None of these showed severe complications, neither bleeding nor perforation. And all of them took good courses. In conclusion, endoscopic resection by this method we developed seems to be excellent in treating esophageal protuberant tumors, furthermore, to be able to treat esophageal flat or depressed lesions, for instance, ep type carcinomas and dysplasias. Hence, we consider that this method is widely applicable to endoscopic resection and patho-histological diagnosis of esophageal tumors.

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