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Evaluation of erhse endoscopic resection with local injection of hypertonic saline epinephrine solution for the treatment of early gastric carcinoma



Evaluation of erhse endoscopic resection with local injection of hypertonic saline epinephrine solution for the treatment of early gastric carcinoma



Stomach & Intestine 26(3): 275-282



The efficacy of ERHSE was evaluated by determining the rate of curative resection, and the rate of residual cancer and the outcome in patients. We studied 164 lesions in 160 patients with early gastric cancer. The lesions consisted of 77 lesions of the elevated type and 87 lesions of the depressed type. Patients were 98 men and 62 women with a mean age of 68.9 years. Characteristics of the ERHSE technique are (1) the use of HSE solution combined with (2) double-fiberscopic method, (3) a precise range of resection along a predetermined line for resection, (4) oral side of a resective material marked injection of ink and (5) histologic study of resective tissues which enables evaluation of the therapy. Successful treatment was achieved by ERHSE alone in 90.0% of the cases. These included 93.5% of the elevated type and 87.4% of depressed type. When 3.7% NaCl hypertonic solution was used, the rate of curative resection was 83.9%. But when 50% glucose was used, the curative rate markedly increased to 94.2%. Five-year survival rate in the 144 cases was 82.3%. ERHSE is an excellent curative technique for early gastric cancer.

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