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Fluorescence of chromatin DNA by an oxazolium scintillator

Fluorescence of chromatin DNA by an oxazolium scintillator

Zeitschrift für Naturforschung. C Journal of Biosciences 47(5-6): 481-482

Aqueous solutions of a yellow and highly fluorescent derivative from dimethyl-POPOP, obtained by treating a chloroform solution of this oxazole scintillator with dimethylsulfate, induce a strong blue-green or yellow-green fluorescence in chromatin DNA under ultraviolet (365 nm) or violet-blue (436 nm) excitation, respectively. It is suggested that this new and selective fluorescence reaction could originate from binding of the oxazolium derivative into the minor groove of DNA.

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Accession: 007355150

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PMID: 1418244

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