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Fluoxetine effects on retention of inhibitory avoidance enhancement by systemic but not intra amygdala injections



Fluoxetine effects on retention of inhibitory avoidance enhancement by systemic but not intra amygdala injections



Psychobiology 20(1): 28-32



Male Sprague-Dawley rats were trained in an inhibitory avoidance task and injected with saline or fluoxetine (15.0 mg/kg i.p.) immediately after training. Fluoxetine significantly facilitated retention assessed on a retention test 48 h later. In contrast, posttraining intra-amygdala injections of fluoxetine (1.0, 3.0, or 10.0 .mu.g) did not modify retention of the inhibitory avoidance task. The findings suggest that the amygdala serotonergic system is not involved in the modulation of memory in this task.

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Accession: 007355860

Download citation: RISBibTeXText

DOI: 10.3758/bf03327157


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