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Insecticides residues and cholinesterase inhibition in zebra finches orally dosed with fenitrothion

Insecticides residues and cholinesterase inhibition in zebra finches orally dosed with fenitrothion

Journal of Environmental Science & Health Part A Environmental Science & Engineering 27(3): 889-902

Fenitrothion residues and cholinesterase (ChE) activities were measured in zebra finches given acute, oral doses of fenitrothion insecticide. Dosage rates were 1.04, 3.80, and 11.36 mg/kg. Residues declined rapidly but were still detectable at trace levels (< 0.005 mg/kg) 96 h after treatment. Peak brain and plasma ChE inhibitions averaged between 50-76% and 79-89%, respectively. Plasma ChE recovered more rapidly (1-4 days) than brain ChE (10 days or more). Brain and plasma ChE inhibitions were positively but weakly, correlated with fenitrothion body burden.

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Accession: 007469265

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