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Moclobemide and clomipramine in endogenous depression. A randomized clinical trial



Moclobemide and clomipramine in endogenous depression. A randomized clinical trial



Acta Psychiatrica Scandinavica 79(6): 523-529



The purpose of this study was to compare moclobemide and clomipramine in endogenous depression according to the Newcastle II classification. Sixty-two patients were allocated to either 300 mg moclobemide or 150 mg clomipramine, both given in 3 daily doses. Improvements occurred over time but differences between treatments were never statistically significant. Dizziness, tremor and anticholinergic symptoms were significantly more frequent with clomipramine.

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Accession: 007556965

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PMID: 2669440


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