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Multiple organ failure with the adult respiratory distress syndrome in homicidal arsenic poisoning



Multiple organ failure with the adult respiratory distress syndrome in homicidal arsenic poisoning



Respiration; International Review of Thoracic Diseases 59(1): 57-61



A 30-year-old man and a 39-year-old woman, who was 28 weeks pregnant, were simultaneously poisoned by eating chocolate containing arsenic trioxide. They developed a picture of multiple organ failure peaking around the 8th to 10th day after ingestion, with the development of life-threatening adult respiratory distress syndrome (ARDS) in both patients. This rarely reported complication of arsenic poisoning was managed successfully by intubation and mechanical ventilation with positive end expiratory pressure in both patients. Hemodynamic and laboratory data are presented supporting the clinical course. Arsenic toxicity further resulted in intrauterine fetal death. The effects of severe arsenic poisoning leading to early multiple organ failure with ARDS as well as to protracted, debilitating polyneuropathy are discussed.

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Accession: 007576080

Download citation: RISBibTeXText

PMID: 1315982

DOI: 10.1159/000196026


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