Section 8
Chapter 7,631

Parameters of early postnatal expression of the tissue specific spectrum of lactate dehydrogenase and isocitrate dehydrogenase activities in pure bred and hybrid rabbits

Boichev, K.; Dragnev, D.

Genetika i Selektsiya 25(1): 69-78


Accession: 007630758

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The dynamics of lactatedehydrogenase (LDH) and isocitratedehydrogenase (ICDH) activities were studied in samples of heart, liver, skeletal muscles, brain, kidneys and lung of newborn and 20-day-old rabbits of the white New Zealand and Californian breeds. The tissue specific effect on the variability of enzymological criteria was evaluated and the effect of ontogenetic development stage and breed appurtenance on the structure of total variability of the interpreted dehydrogenases within the individual tissues was analyzed. The criteria about the effect of tissue differentiation regarding LDH ranged from 77.85% to 97.89%. The factor age caused 71.12% to 91.54% of the tissue specific variability of the enzyme, while the role of breed appurtenance wash greatest in brain tissue (5.77%). On the background of the relatively less important intertissue differences in the newborn, the effect of the "tissue" factor in the group of 20-day-old offspring represented from 81.90% to 88.87% of the total variability of ICDH, while the stage of ontogenetic development determined 19.71% to 88.12% of its tissue specific variability and the maximal value of the analogous parameter for breed appurtenance reached only 21.92%.

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