+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Simulation of the dynamics of decompression sickness bubbles and the generation of new bubbles

Simulation of the dynamics of decompression sickness bubbles and the generation of new bubbles

Undersea Biomedical Research 18(4): 333-345

This communication introduces a system of equations for simulating the dynamics of growth and decay of decompression bubbles. The equations are solved by a numerical method and account for gas diffusion, the action of surface tension, tissue N2 washout by blood, and the rate of ascent from depth. The simultaneous demonstrate how inward diffusion of N2 can generate a persistent gas bubble from a nucleation process or a nucleus (these are provisionally defined as entities that can give rise to a small bubble of a certain size); an explosive positive-feedback loop is set off as the enlarging radius decreases the pressure due to surface tension. Generation of persistent bubbles is most likely during ascent from depth when PN2 inside any gas phase is decreasing rapidly and PN2 outside is still high before appreciable tissue washout has occurred. The "susceptibility" for the generation of a persistent bubble at any time can be defined as the reciprocal of the difference, at that time, between partial pressure of the nitrogen in tissue and in a spherical bubble of the size that is characteristic of the nucleation process or nucleus; susceptibility is less when ascent is slow because PN2 in bubbles stays high while washout removes N2 from the tissue.

(PDF emailed within 1 workday: $29.90)

Accession: 007794140

Download citation: RISBibTeXText

PMID: 1887520

Related references

Bubbles in the blood during hyperbaric decompression abstract sheep decompression sickness. Proc Int Union Physiol Sci: 412, 1968

Doppler ultrasonic monitoring of intra vascular decompression bubbles in relation to prevention of decompression sickness. Journal of UOEH 6(SUPPL): 55-56, 1984

Gas micronuclei that underlie decompression bubbles and decompression sickness have not been identified. Diving and Hyperbaric Medicine 49(1): 64, 2019

Intracardial bubbles during decompression to altitude in relation to decompression sickness in man. Aviation, Space, and Environmental Medicine 47(2): 113-116, 1976

A physiological model of the interaction between tissue bubbles and the formation of blood-borne bubbles under decompression. Physics in Medicine and Biology 51(9): 2321-2338, 2006

Density of decompression bubbles and competition for gas among bubbles, tissue, and blood. Journal of Applied Physiology 75(5): 2293-2301, 1993

Studies on the origin of intravascular bubbles: The appearance bubbles in rat adipose tissue after decompression following exposure to high pressure. Journal of Saitama Medical School 19(4): 447-454, 1992

Decompression sickness and intravenous gas bubbles. Internationale Zeitschrift für Angewandte Physiologie, Einschliesslich Arbeitsphysiologie 19: 67-79, 1961

"Mute" gas bubbles and their role in decompression sickness. Voenno-Meditsinskii Zhurnal 9: 56-59, 1969

Ultrasonic imaging of in vivo bubbles in decompression sickness. Ultrasonics 9(4): 225-234, 1971

Intracardial gas bubbles and decompression sickness while flying at 9,000 m within 12-24 h of diving. Aviation, Space, and Environmental Medicine 49(11): 1314-1318, 1978

Correlation between decompression sickness and circulating bubbles in 232 divers. Undersea Biomedical Research 6(1): 99-107, 1979

Intravascular doppler detected bubbles and decompression sickness. Undersea Biomedical Research 17(SUPPL): 34-35, 1990

Correlation between decompression sickness and circulating bubbles in 211 divers. Undersea Biomedical Research 5(1 SUPPL): 30, 1978

Systemic intravascular and extravascular air bubbles in type I decompression sickness. Emergency Medicine Journal 32(2): 104, 2015