EurekaMag.com logo
+ Site Statistics
References:
53,869,633
Abstracts:
29,686,251
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Studies on fluoride excretion in human whole saliva and its relation to flow rate and plasma fluoride levels



Studies on fluoride excretion in human whole saliva and its relation to flow rate and plasma fluoride levels



Caries Research 23(4): 243-246



Five volunteers participated in two separate experiments where whole saliva was collected without stimulation or with stimulation by chewing on paraffin wax. The saliva was collected continuously for 120 min after ingestion of 1 mg fluoride as NaF. Blood was collected at intervals throughout the experiments. The results showed that the concentration of fluoride in whole saliva mirrored the fluoride concentration in plasma, but at a lower level. Variations in salivary flow rate (0.34 .+-. 0.15 ml/min for unstimulated and 1.06 .+-. 0.28 ml/min for stimulated) did not affect the salivary fluoride concentration. The amount of fluoride excreted into stimulated whole saliva was significantly correlated with the salivary flow rate, with a correlation coefficient of 0.98. The fraction of the ingested fluoride dose recovered in whole saliva within 2 h was 0.05 .+-. 0.02 and 0.18 .+-. 0.09% for the unstimulated and the stimulated whole saliva, respectively.

(PDF emailed within 0-6 h: $19.90)

Accession: 007831942

Download citation: RISBibTeXText

PMID: 2790857

DOI: 10.1159/000261185



Related references

Studies on fluoride concentrations in human submandibular/sublingual saliva and their relation to flow rate and plasma fluoride levels. Journal of Dental Research 68(2): 146-149, 1989

Influence of flow rate, pH and plasma fluoride concentrations on fluoride concentration in human parotid saliva. Archives of Oral Biology 34(3): 191-194, 1989

The direct determination of fluoride in human saliva by a inst fluoride electrode fluoride levels in parotid saliva after ingestion of single doses of sodium fluoride. Archives of Oral Biology 13(2): 203-213, 1968

The direct determination of fluoride in human saliva by a fluoride electrode. Fluoride levels in parotid saliva after ingestion of single doses of sodium fluoride. Archives of Oral Biology 13(2): 203-213, 1968

Studies on the metabolism of sodium fluoride: 1. Plasma fluoride in relation to dietary fluoride in dairy cattle. 2. Effects of fluoride on growth and metabolism of HeLa cells. Dissertation Abstracts, 28B 529-530, 1967

Fluoride concentrations in saliva after single oral doses and their relation to plasma fluoride. Scandinavian Journal of Dental Research 85(1): 16-17, 1977

The relationship between plasma fluoride, urinary excretion rate and urine fluoride concentration in man. Journal of Occupational Medicine. 25(10): 745-748, 1983

Fluoride in mixed human saliva after different topical fluoride treatments and possible relation to caries inhibition. Community Dentistry & Oral Epidemiology 10(3): 124-129, 1982

Correlations between fluoride concentrations of human plasma saliva and sweat following low and high fluoride intake. Helvetica Odontologica Acta 17(2): 59-60, 1973

Renal fluoride excretion and plasma fluoride levels during and after enflurane anesthesia are dependent on urinary pH. Anesthesiology 54(1): 48-52, 1981

Effect of fluoride dosage on human parotid saliva fluoride levels. Archives of Oral Biology 17(9): 1303-1309, 1972

Fluoride levels in human parotid saliva following ingestion of fluoride compounds of varying solubility. Journal of Dental Research 56(12): 1521-1525, 1977

Salivary fluoride excretion and its relation to plasma fluoride. Caries Research: 180, 1987

Plasma fluoride concentration and urinary fluoride excretion in children following application of the fluoride-containing varnish Duraphat. Caries Research 14(4): 185-189, 1980

Urinary fluoride excretion in children exposed to fluoride toothpaste and to different water fluoride levels in a tropical area of Brazil. Brazilian Dental Journal 19(3): 214-218, 2008