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Studies on free fatty acids in human semen

Studies on free fatty acids in human semen

Journal of Tokyo Medical College 48(4): 399-408

Thirty-eight free fatty acids from low to high molecule in human seminal plasma was analyzed quantitatively using high performance liquid chromatography (HPLC) which was established by Yanagisawa et al. Furthermore, 14C-acetic acid was incubated in human semen and the incorporation of radioactivity into free fatty acids was studied. Consequently, novel findings on the synthetic ability and metabolic pattern was obtained as follows: Reduction of free fatty acids was observed in seminal plasma with azoospermia due to vasectomy. Fatty acids with less than C-10 were considered to have originated from the sperm cell. Incorporation of the radioactivity into fatty acids was marked not only in those with even-numbered carbons but also especially in those with uneven-numbered carbons. Metabolic activity from 14C-acetic acid to lactic acid was especially remarkable.

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Accession: 007831968

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