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Studies on hindered phenols iii. synthesis of carbon 14 labeled racemic 5 4 6 hydroxy 2 5 7 8 tetramethylchroman 2 ylmethoxybenzyl 5 carbon 14 thiazolidine 2 4 dione carbon 14 labeled cs 045



Studies on hindered phenols iii. synthesis of carbon 14 labeled racemic 5 4 6 hydroxy 2 5 7 8 tetramethylchroman 2 ylmethoxybenzyl 5 carbon 14 thiazolidine 2 4 dione carbon 14 labeled cs 045



Journal of Labelled Compounds and Radiopharmaceuticals 28(8): 911-920



A synthetic procedure for producing (+)-5-[4-(6-hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl]-5-14C-thiazolidine-2, 4-dione (14C-labelled CS-045) is described. The radiolabel is introduced using [5-14C] thiazolidine-2, 4-dione, as shown in the scheme.

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