Section 8
Chapter 7,871

The activities of aminoacyl transfer rna synthetase phosphatase and aminoacyl transfer rna synthetases in mpc 11 and krebs ii ascites cells

Pryme, I.F.; Berg, B.H.

Cancer Letters 58(1-2): 119-124


ISSN/ISBN: 0304-3835
Accession: 007870886

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The activity of aminoacyl-tRNA synthetase phosphatase as well as the activities of aminoacyl-tRNA synthetases in Krebs II ascites cells and MPC-11 cells have been investigated. The activity of the phosphatase was greater in the tumor cells than in normal tissues. The aminoacyl-tRNA synthetase activities were 100-300 times higher than the activities found in the uterus of ovariectomized mice, but not very diffrent from the activities found in the liver. The influence of cyclic AMP, 2-deoxyadenosine-3-phosphate and 2-deoxyguanosine-3-phosphate on the growth of MPC-11 cells grown in suspension culture, was also investigated.

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