EurekaMag
+ Translate
+ Most Popular
Cunninghamia lanceolata plantations in China
Mammalian lairs in paleo ecological studies and palynology
Studies on technological possibilities in utilization of anhydrous milk fat for production of recombined butter-like products
Should right-sided fibroelastomas be operated upon?
Large esophageal lipoma
Apoptosis in the mammalian thymus during normal histogenesis and under various in vitro and in vivo experimental conditions
Poissons characoides nouveaux ou non signales de l'Ilha do Bananal, Bresil
Desensitizing efficacy of Colgate Sensitive Maximum Strength and Fresh Mint Sensodyne dentifrices
Administration of fluid by subcutaneous infusion: revival of a forgotten method
Tundra mosquito control - an impossible dream?
Schizophrenia for primary care providers: how to contribute to the care of a vulnerable patient population
Geochemical pattern analysis; method of describing the Southeastern limestone regional aquifer system
Incidence of low birth weights in a hospital of Mexico City
Tabanidae
Graded management intensity of grassland systems for enhancing floristic diversity
Microbiology and biochemistry of cheese and fermented milk
The ember tetra: a new pygmy characid tetra from the Rio das Mortes, Brazil, Hyphessobrycon amandae sp. n. (Pisces, Characoidei)
Risk factors of contrast-induced nephropathy in patients after coronary artery intervention
Renovation of onsite domestic wastewater in a poorly drained soil
Observations of the propagation velocity and formation mechanism of burst fractures caused by gunshot
Systolic blood pressure in a population of infants in the first year of life: the Brompton study
Haematological studies in rats fed with metanil yellow
Studies on pasteurellosis. I. A new species of Pasteurella encountered in chronic fowl cholera
Dormancy breaking and germination of Acacia salicina Lindl. seeds
therapy of lupus nephritis. a two-year prospective study

The effect of multiple ivermectin treatments on infection of Simulium ochraceum with Onchocerca volvulus


The effect of multiple ivermectin treatments on infection of Simulium ochraceum with Onchocerca volvulus



American Journal of Tropical Medicine and Hygiene 40(5): 501-506



ISSN/ISBN: 0002-9637

PMID: 2729507

Ivermectin, a broad spectrum antiparasitic agent, interrupted the uptake of Onchocerca volvulus microfilariae by Simulium ochraceum from a group of human volunteers given multiple oral treatments of 200 micrograms/kg body weight. Two treatments, given at 7 month intervals, resulted in almost complete suppression of developing or infective larvae in the vector population for a 6 month period. The overall decline following 2 treatments was an order of magnitude lower than the pretreatment level. Ivermectin administration, in addition to the beneficial clinical effects, also could be useful for the control of human onchocerciasis as an independent measure or in conjunction with vector control.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 007890370

Download citation: RISBibTeXText

Related references

Effect of semiannual treatments of ivermectin on the prevalence and intensity of Onchocerca volvulus skin infection, ocular lesions, and infectivity of Simulium ochraceum populations in southern Mexico. American Journal of Tropical Medicine and Hygiene 52(5): 429-434, 1995

Determination of sample sizes for the estimation of Onchocerca volvulus (Filarioidea: Onchocercidae) infection rates in biting populations of Simulium ochraceum s.l. (Diptera: Simuliidae) and its application to ivermectin control programs. Journal of Medical Entomology 35(5): 745-757, 1998

Quantitative aspects of the infection of Simulium ochraceum by Onchocerca volvulus. Tropenmedizin und Parasitologie 28(2): 235-243, 1977

Quantitative aspects of the infection of Simulium ochraceum by Onchocerca volvulus: the relation of skin microfilarial density to vector infection. Tropenmedizin und Parasitologie 31(4): 475-478, 1980

Development of Onchocerca volvulus in Simulium ochraceum and Simulium metallicum. American Journal of Tropical Medicine and Hygiene 28(3): 491-495, 1979

Comparative studies on the affinities of 2 black flies simulium metallicum and simulium ochraceum for the larvae of onchocerca volvulus in guatemala. Medical Entomology and Zoology 31(4): 261-270, 1980

Comparative studies on the affinities of two black flies, Simulium metallicum and Simulium ochraceum for the larvae of Onchocerca volvulus in Guatemala. Eisei dobutsu = Japanese journal of sanitary zoology 31(4): 261-270, 1980

Detection of Onchocerca volvulus infection in Simulium ochraceum sensu lato: comparison of a Pcr assay and fly dissection in a Mexican hypoendemic community. Parasitology 119(6): 613-619, 1999

Detection of Onchocerca volvulus infection in Simulium ochraceum sensu lato: comparison of a PCR assay and fly dissection in a Mexican hypoendemic community. Parasitology 119: 613-619, 1999

Artificial feeding of simulium vectors of human and bovine onchoceriasis onchocerca volvulus onchocerca gutturosa simulium ornatum simulium damnosum simulium woodi simulium vorax simulium nyasalandicum. Bulletin Of The World Health Organization: 957-966, 1968

Age structure of Simulium ochraceum and transmission of Onchocerca volvulus in Mexico. Journal of the American Mosquito Control Association 8(3): 310, 1992

Reduction in the ingestion of Onchocerca volvulus microfilariae by Simulium ochraceum after DEC provocation. Japanese journal of parasitology 36(4): 284-286, 1987

The gonotrophic cycle of wild Simulium ochraceum and the associated development of Onchocerca volvulus. American Journal of Tropical Medicine and Hygiene 34(2): 302-309, 1985

Limited fly load and development of Onchocerca volvulus microfilariae in Guatemalan Simulium ochraceum. Journal of Helminthology 55(3): 189-196, 1981

Post-prandial transportation and maintenance of Simulium ochraceum infected with Onchocerca volvulus. American Journal of Tropical Medicine and Hygiene 26(1): 75-79, 1977