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Therapy for a severe hirsute woman with combination of cimetidine and oral contraceptive pill a case report


Therapy for a severe hirsute woman with combination of cimetidine and oral contraceptive pill a case report



Journal of Kyoto Prefectural University of Medicine 99(2): 239-246



A 18 year-old hirsute woman was treated for 9 months with combination of cimetidine (600-800 mg/day, continuous) and oral contraceptive pill (norethindrone 1.0 mg/day and ethynylestradiol 0.05 mg/day; D5 .apprx. D25). Consequently, her body hair score was estimated to be slightly reduced from 36 points to 31 points with using semiquantitative method of Ferriman and Gallwey. Afterwards, the hair score was remarkably reduced to 15 points by the oral administration of cyproterone acetate. Thus, a combination therapy of cimetidine and oral contraceptive pill is not very effective when compared to cyproterone acetate for a treatment of hirsutism.

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Accession: 007946840

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