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A case of giant condyloma acuminatum. Differential diagnosis of giant condylomas from Buschke-Loewenstein tumours



A case of giant condyloma acuminatum. Differential diagnosis of giant condylomas from Buschke-Loewenstein tumours



Hautarzt 44(12): 795-799



We report on a 67-year-old man with a large papillomatous tumour of the penis clinically resembling verrucous carcinoma. HPV 6 and HPV 11 DNA could be isolated by hybridization techniques. The tumour showed exclusively exophytic growth with anastomosing acanthosis and papillomatosis. Groups of vacuolated cells were present in the spinous and granular layers. Endophytic and destructive proliferations and cytologic criteria of malignancy were absent. This tumor was a giant condyloma acuminatum and not either a Buschke-Lowenstein tumour or a verrucous carcinoma. There was no recurrence 2 years after local excision. The differential diagnosis of giant condylomas and Buschke-Lowenstein tumours is discussed.

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Accession: 008024927

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