A digital brain atlas and its application to the visceral neuraxis

Funka-Lea, G.D.; Schwaber, J.S.

Journal of Neuroscience Methods 54(2): 253-260


ISSN/ISBN: 0165-0270
PMID: 7869756
DOI: 10.1016/0165-0270(94)90197-x
Accession: 008036574

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We describe the details and application of a digital brain atlas for the comparison and integration of graphical neurobiological data. The atlas consists of multiple sets of high-resolution video images acquired from histological tissue sections representing a 3-dimensional (3D) volume of an exemplar rat brain. Through an interactive graphical interface running on a standard computer workstation, experimental data is brought into register with the atlas. Once in the atlas, coordinate reference frame data can be compared, analyzed, and visualized in 3 dimensions. We demonstrate the aridity and usefulness of the digital brain atlas with a series of results on the visceral neuraxis in the rat.