Section 9
Chapter 8,094

Acalculous cholecystitis and septicemia caused by non-O1 Vibrio cholerae: First reported case and review of biliary infections with Vibrio cholerae

West, B.C.; Silberman, R.; Otterson, W.N.

Diagnostic Microbiology and Infectious Disease 30(3): 187-191


ISSN/ISBN: 0732-8893
PMID: 9572025
DOI: 10.1016/s0732-8893(97)00235-6
Accession: 008093137

The first case of septicemic acute acalculous cholecystitis caused by non-O1 Vibrio cholerae is described in a healthy traveler, and biliary tract infections from V. cholerae are reviewed. Immediately after a vacation in Cancun, Mexico, a 55-year-old man developed acute cholecystitis. Blood and bile cultures grew non-O1 V. cholerae. At surgery, the gallbladder was acalculous, inflamed, distended, and nearly ruptured. Pathogenetic factors may have included diarrhea prophylaxis with bismuth subsalicylate, distension of the gallbladder from illness-induced fasting, and bacterial toxins in the gallbladder. The patient received i.v. cephapirin, followed by oral cephradine for a total of 10 days, and he made a quick and complete recovery. V. cholerae should be considered in the differential diagnosis of persons from endemic areas who present with cholecystitis or acute jaundice.

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