EurekaMag.com logo
+ Site Statistics
References:
53,214,146
Abstracts:
29,074,682
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Additive effects of pituitary adenylate cyclase. Activating polypeptide and growth hormone releasing hormone on the release of growth hormone from cultured bovine anterior pituitary cells






Animal Science & Technology 66(4): 330-335

Additive effects of pituitary adenylate cyclase. Activating polypeptide and growth hormone releasing hormone on the release of growth hormone from cultured bovine anterior pituitary cells

Additive effects of pituitary adenylate cyclase-activating polypeptide (PACAP) with growth hormone releasing hormone (GHRH) on the release of growth hormone (GH) were studied in cultured bovine anterior pituitary cells. The combined stimulatory effects of 10-7 M PACAP and GHRH (10-12, 10-10 or 10-8 M) together on the release of GH were similar to those for either PACAP or GHRH alone. When 10-8 M PACAP and 10-8 M GHRH were added together, the release of GH induced by both peptides was significantly greater than those by either PACAP or GHRH alone (P lt 0.05). When 10-9 M PACAP and 10-8 M GHRH were added together, the release of GH induced by both peptides was significantly greater than those of either PACAP or GHRH alone (P lt 0.05). The additive effects on the release of GH were not observed when PACAP (10-8 M or 10-9 M) was combined with either 10-10 M or 10-12 M GHRH. These findings suggest that PACAP interacts additionally with GHRH in stimulating growth hormone release under limited concentrations of both peptides in cattle.

(PDF 0-2 workdays service: $29.90)

Accession: 008110262



Related references

Effects of pituitary adenylate cyclase-activating polypeptide , prostaglandin E-2 and growth hormone releasing factor on the release of growth hormone from cultured bovine anterior pituitary cells in vitro. Domestic Animal Endocrinology 11(4): 331-337, 1994

Effects of pituitary adenylate cyclase-activating polypeptide (PACAP), prostaglandin E-2 (PGE-2) and growth hormone releasing factor (GRF) on the release of growth hormone from cultured bovine anterior pituitary cells in vitro. Domestic Animal Endocrinology 11(4): 331-337, 1994

Effects of pituitary adenylate cyclase- activating polypeptide on the release of growth hormone , luteinizing hormone , and prolactin from cultured bovine anterior pituitary cells in vitro. Animal Science & Technology 65(11): 993-998, 1994

Effects of pituitary adenylate cyclase-activating polypeptide (PACAP) on the release of growth hormone (GH), luteinizing hormone (LH), and prolactin (PRL) from cultured bovine anterior pituitary cells in vitro. Animal Science and Technology 65(11): 993-998, 1994

Effects of pituitary adenylate cyclase-activating polypeptide 27 and PACAP 38 on the release of luteinizing hormone from cultured bovine anterior pituitary cells. Journal of Reproduction & Development 41(1): 15-20, 1995

Pituitary adenylate cyclase activating polypeptide, growth hormone (GH)-releasing peptide and GH-releasing hormone stimulate GH release through distinct pituitary receptors. Endocrinology 130(2): 939-944, 1992

Effects of pituitary adenylate cyclase-activating polypeptide on cAMP formation and growth hormone release from chicken anterior pituitary cells. Forssmann, W -G, Said, S I Annals of the New York Academy of Sciences; VIP, PACAP, and related peptides 471-474, 1998

Effects of pituitary adenylate cyclase-activating polypeptide (PACAP) on cAMP formation and growth hormone release from chicken anterior pituitary cells. Annals of the New York Academy of Sciences 865: 471-474, 1999

Effects of pituitary adenylate cyclase-activating polypeptide (PACAP) 27 and PACAP 38 on the release of luteinizing hormone (LH) from cultured bovine anterior pituitary cells. Journal of Reproduction and Development 41(1): 15-20, 1995

Molecular evolution of the growth hormone-releasing hormone/pituitary adenylate cyclase-activating polypeptide gene family. Functional implication in the regulation of growth hormone secretion. Journal of Molecular Endocrinology 25(2): 157-168, 2000