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Association of the 94 KDa glucose-regulated protein with immunoglobulin heavy chain binding protein (BiP)


Association of the 94 KDa glucose-regulated protein with immunoglobulin heavy chain binding protein (BiP)



Korean Journal of Zoology 35(4): 456-465



The 94 KDa glucose-regulated protein (grp 94), one of stress proteins, is a Ca-2+-binding protein in the endoplasmic reticulum (ER). In this study, the possible effect of Ca-2+ on the native conformation of grp 94 was examined. When the purified grp 94 was analyzed by gel filtration in the presence of either EGTA or CaCl-2, it was eluted with apparent molecular weight (MW) of 100 KDa in both cases.

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