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Bio-metabolic disposition of metanil yellow, orange II and their blend by caecal microflora of rats

Singh, S.; Das, M.; Khanna, S.K.

Indian Journal of Experimental Biology 33(7): 543-544

1995

ISSN/ISBN: 0019-5189
PMID: 7590962
Accession: 008224556
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Caecal microflora were employed to study the degradation pattern, with time course of Metanil yellow and Orange II-two extensively used non-permitted food colours. Metanil yellow and Orange II showed the respective Degradation Index 50 (DI 50) values of 369 and 288 min. However, the blend of Metanil yellow and Orange II (1: 1) resulted in the D 1 50. value of 288 min. Metanil yellow. Orange II and their blend were resolved into respective metabolites in different solvent systems.

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Related References

Ramchandani, S.; Das, M.; Khanna, S.K. 1994: Effect of metanil yellow, orange II and their blend on hepatic xenobiotic metabolizing enzymes in rats Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association 32(6): 559-563
Singh, R.L.; Khanna, S.K.; Singh, G.B. 1988: Acute and short-term toxicity of a popular blend of metanil yellow and orange Ii in albino rats Indian Journal of Experimental Biology 26(2): 105-111
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