EurekaMag.com logo
+ Site Statistics
References:
52,725,316
Abstracts:
28,411,598
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

CSF transthyretin in patients with depression


American Journal of Psychiatry 150(5): 813-815
CSF transthyretin in patients with depression
Some depressed patients may suffer from restricted central hypothyroidism, which could occur if levels of the thyroid hormone transport protein transthyretin were low. CSF transthyretin was measured in eight inpatients with refractory major depression and nine neurological patients. The depressed patients had significantly lower transthyretin levels than the comparison subjects, suggesting that central hypothyroidism, with normal peripheral thyroid concentrations, could occur in some depressed patients.


Accession: 008253055

PMID: 8480830

DOI: 10.1176/ajp.150.5.813



Related references

Pressure-volume relationships in patients with transthyretin (ATTR) cardiac amyloidosis secondary to V122I mutations and wild-type transthyretin: Transthyretin Cardiac Amyloid Study (TRACS). Circulation. Heart Failure 4(2): 121-128, 2011

Effects of tafamidis on transthyretin stabilization and clinical outcomes in patients with non-Val30Met transthyretin amyloidosis. Journal of Cardiovascular Translational Research 6(6): 1011-1020, 2014

Two novel variants of transthyretin identified in Japanese cases with familial amyloidotic polyneuropathy: transthyretin (Glu42 to Gly) and transthyretin (Ser50 to Arg). Biochemical and Biophysical Research Communications 169(3): 1117-1121, 1990

Two novel variants of transthyretin identified in japanese cases with familial amyloidotic polyneuropathy transthyretin glutamine 42 to glycine and transthyretin serine 50 to arginine. Biochemical & Biophysical Research Communications 169(3): 1117-1121, 1990

Allele specific expression of the transthyretin gene in swedish patients with hereditary transthyretin amyloidosis (ATTR V30M) is similar between the two alleles. Plos One 7(11): E49981-E49981, 2013

Proportion of wild-type transthyretin in truncated compared to full-length ATTR An analysis on transplanted transthyretin T60A amyloidosis patients. 2009

Wild-type transthyretin significantly contributes to the formation of amyloid fibrils in familial amyloid polyneuropathy patients with amyloidogenic transthyretin Val30Met. Human Pathology 42(2): 236-243, 2011

THAOS - The Transthyretin Amyloidosis Outcomes Survey: initial report on clinical manifestations in patients with hereditary and wild-type transthyretin amyloidosis. Current Medical Research and Opinion 29(1): 63-76, 2013

Transthyretin is involved in depression-like behaviour and exploratory activity. Journal of Neurochemistry 88(5): 1052-1058, 2004

Low cerebrospinal fluid transthyretin levels in depression: correlations with suicidal ideation and low serotonin function. Biological Psychiatry 60(5): 500-506, 2006