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Carotenoid mutants of Mucor circinelloides



Carotenoid mutants of Mucor circinelloides



Botanica Acta 108(4): 396-400



The wild-type of the filamentous fungus Mucor circinelloides accumulates the yellow pigment beta-carotene. At a continuous blue-light fluence rate of 0.1 W/m-2 the beta-carotene content increases about eight fold over the dark controls. Among the mutants isolated after exposure of spores to either N-methyl-N'-nitro-Nnitrosoguanidine or ICR-170, a red mutant accumulating lycopene, white mutants accumulating phytoene and white mutants without carotenoids were found. The biosynthesis of carotenoids in M. circinelloides shows similarities with that of the fungus Phycomyces blakesleeanus such as the presence of mutants in the same structural genes and the induction by light of the pathway. However, negative end-product regulation by beta-carotene on the biosynthetic pathway, as in Phycomyces, is absent in M. circinelloides. In contrast to Phycomyces carB and carR mutants, carotenoids in corresponding mutants of M. circinelloides are photoinduced.

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Accession: 008267807

Download citation: RISBibTeXText

DOI: 10.1111/j.1438-8677.1995.tb00511.x


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