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Combination of antimicrobic drugs: I. Mechanism of interaction



Combination of antimicrobic drugs: I. Mechanism of interaction



Veterinarski Glasnik 49(4): 247-251



Knowledge of antibiotics and their manner of application are of great importance in veterinary medicine. Irrespective of the fact that many infective diseases of domestic animals can be treated with one, antimicrobic drug, we are often witness to the simultaneous application of several antibiotics. In most cases, the applied antibiotics act independently of each other. in fact the total affect is equal to the effect of the active component. However, interaction can sometimes take place between antibiotics in the form of a stepped up effect when synergism occurs, or a played down effect when antagonism occurs between the applied drugs.

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