+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Comorbidity of axis I and axis II disorders



Comorbidity of axis I and axis II disorders



American Journal of Psychiatry 152(4): 571-578



Objective: In light of continuing controversies concerning the DSM-III-R system for diagnosing personality disorders, their construct validity, and the assignment of disorders to a particular axis, the authors studies patterns of axis I-axis II comorbidity. Method: Semistructured interviews were used to assess axis I and axis II disorders in 200 inpatients and outpatients. Odds ratios were calculated to determine significant comorbidity between classes of current axis I disorders and axis II personality disorders diagnosed according to two methods and defined at two diagnostic thresholds. Distributions of personality disorder traits were also compared in patients with and without axis I disorders. Results: Significantly elevated odds ratios were found for co-occurrence of current mood disorders with avoidant and dependent personality disorders; anxiety disorders with borderline, avoidant and dependent personality disorders; psychotic disorders with schizotypal, borderline and dependent personality disorders; psychoactive substance use disorders with borderline and histrionic personality disorders; and eating disorders with schizotypal, borderline, and avoidant personality disorders. These results held when conservative and liberal definitions of personality disorders were used. Non-specific axis I and axis II associations were confirmed for distributions of personality disorder traits gt Conclusions: Significant associations occurred between most axis I classes of disorders and axis II disorders and traits in more than one cluster. All axis I classes of disorders except mood disorders co-occurred with borderline personality disorder; however, patients with mood disorders had elevated levels of borderline traits. When any personality disorder was present, there were significant odds that a mood, anxiety, psychotic, or eating disorder would also be present; psychoactive substance use disorders, in contrast, significant co-occurred with borderline and histrionic personality disorders.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 008347380

Download citation: RISBibTeXText

PMID: 7694906

DOI: 10.1176/ajp.152.4.571


Related references

Should an assessment of Axis I comorbidity be included in the initial diagnostic assessment of mood disorders? Role of QIDS-16-SR total score in predicting number of Axis I comorbidity. Journal of Affective Disorders 148(2-3): 256-264, 2013

Comorbidity of axis I and axis II diagnoses in a sample of Egyptian patients with neurotic disorders. Comprehensive Psychiatry. 37(2): 95-101, 1996

Suicidal events among pathological gamblers: the role of comorbidity of axis I and axis II disorders. Psychiatry Research 225(3): 413-419, 2015

Prevalence and comorbidity of axis I and axis II disorders among treatment refractory adolescents admitted for specialized psychotherapy. Journal of Personality Disorders 25(6): 842-850, 2011

Comorbidity of axis I and axis II disorders in patients who attempted suicide. American Journal of Psychiatry 160(8): 1494-1500, 2003

Comorbidity versus misdiagnosis of axis II and axis III disorders. American Journal of Psychiatry 146(10): 1356, 1989

Heuristic models of comorbidity of axis I and axis II disorders. Journal of Personality Disorders 11(3): 260-269, 1997

Lack of remorse in antisocial personality disorder: sociodemographic correlates, symptomatic presentation, and comorbidity with Axis I and Axis II disorders in the National Epidemiologic Survey on Alcohol and Related Conditions. Comprehensive Psychiatry 47(4): 289-297, 2006

Early-onset of illicit substance use is associated with greater axis-II comorbidity, not with axis-I comorbidity. Drug & Alcohol Dependence 59(3): 305-308, 2000

Gender differences in axis I and axis II comorbidity in patients with borderline personality disorder. Psychopathology 42(4): 257-263, 2009

Axis I and Axis II comorbidity in panic/agoraphobic patients with and without suicidal ideation. Psychiatry Research 88(2): 153-161, 1999

Relations between Obsessive-Compulsive Disorder and personality: beyond Axis I-Axis II comorbidity. Journal of Anxiety Disorders 20(6): 695-717, 2006