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Comparison of vidas (Clostridium difficile toxin-A assay and premier Clostridium difficile toxin-A assay to cytotoxin B tissue culture assay for the detection of toxins of Clostridium difficile



Comparison of vidas (Clostridium difficile toxin-A assay and premier Clostridium difficile toxin-A assay to cytotoxin B tissue culture assay for the detection of toxins of Clostridium difficile



Diagnostic Microbiology and Infectious Disease 17(1): 7-12



Damage to the intestinal mucosa by Clostridium difficile (CD) is toxin mediated. Two enzyme immunoassays (EIAs) for toxin-A detection, the automated Vitek immunodiagnostic assay system CDA (Vidas CDA), and the Premier toxin A (Premier) were tested for their ability to detect toxin A in 301 stool samples and compared with an in-house tissue culture assay for toxin B (TCA). Of these 301 samples, 49 were TCA positive and 252 were TCA negative.

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Accession: 008364510

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