Continuous veno-venous hemodiafiltration using bicarbonate dialysate
Roy, D.; Hogg, R.J.; Wilby, P.A.; Matthews, N.; Henning, P.H.; Jureidini, K.F.
Pediatric Nephrology 11(6): 680-683,.
We report our experience with 11 children treated by continuous veno-venous hemodiafiltration. The median age was 5.0 years (range 3 days to 14 years). Access was via dual-lumen subclavian or femoral vein catheters. Hemofilters were chosen on the basis of patient size and dialysis requirements. Bicarbonate-buffered dialysis solution was prepared shortly before use by supplementation of a specially prepared base solution with commercially available electrolyte solutions. The mean ultrafiltration rate was 37.4 +- 27 ml/kg body weight per hour. Urea and creatinine clearances were 15.1 +- 6.4 ml/kg body weight per min and 16.4 +- 8.4 ml/kg body weight per min, respectively. Metabolic acidosis was readily controlled in all patients. Of the 11 patients, 7 ultimately recovered normal renal function.