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References:
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Marsac, C.; Stansbie, D.; Bonne, G.; Cousin, J.; Jehenson, P.; Benelli, C.; Leroux, J.P.; Lindsay, G. 1993: Defect in the lipoyl-bearing protein X subunit of the pyruvate dehydrogenase complex in two patients with encephalomyelopathy. Journal of Pediatrics 123(6): 915-920
Crackower, M.A.; Motoyama, J.; Tsui, L.C. 1998: Defect in the maintenance of the apical ectodermal ridge in the Dactylaplasia mouse. Developmental Biology 201(1): 78-89
Muro, H.; Shirasawa, H.; Kosugi, I.; Nakamura, S. 1993: Defect of Fc receptors and phenotypical changes in sinusoidal endothelial cells in human liver cirrhosis. American Journal of Pathology 143(1): 105-120
Witte, T.; Dumoulin, F.L.; Gessner, J.E.; Schubert, J.; Götze, O.; Neumann, C.; Todd, R.F.; Deicher, H.; Schmidt, R.E. 1993: Defect of a complement receptor 3 epitope in a patient with systemic lupus erythematosus. Journal of Clinical Investigation 92(3): 1181-1187
Sato, T.; Magata, K.; Koga, N.; Mitsumoto, Y. 1998: Defect of an early event of glucose metabolism in skeletal muscle of the male Otsuka Long-Evans Tokushima Fatty (OLETF) rat, a non-insulin-dependent diabetes mellitus (NIDDM) model. Biochemical and Biophysical Research Communications 245(2): 378-381
Lin, C.Y.; Lin, C.C.; Chang, G.J.; King, C.C. 1997: Defect of cell-mediated immune response against hepatitis B virus: an indication for pathogenesis of hepatitis-B-virus-associated membranous nephropathy. Nephron 76(2): 176-185
Romano, M.F.; Turco, M.C.; Stanziola, A.; Giarrusso, P.C.; Petrella, A.; Tassone, P.; van Lier, R.; Venuta, S.; Formisano, S. 1993: Defect of interleukin-2 production and T cell proliferation in atopic patients: restoring ability of the CD28-mediated activation pathway. Cellular Immunology 148(2): 455-463
Deleuze, J.F.; Jacquemin, E.; Dubuisson, C.; Cresteil, D.; Dumont, M.; Erlinger, S.; Bernard, O.; Hadchouel, M. 1996: Defect of multidrug-resistance 3 gene expression in a subtype of progressive familial intrahepatic cholestasis. Hepatology 23(4): 904-908
Ezaki, J.; Wolfe, L.S.; Kominami, E. 1995: Defect of proteolysis of mitochondrial ATP synthase subunit C in neuronal ceroid lipofuscinosis. Gerontology 41(Suppl): 259-269
Benedetti, E.; Pedone, C.; Pavone, V.; Di Blasio, B.; Saviano, M.; Fattorusso, R.; Crisma, M.; Formaggio, F.; Bonora, G.M.; Toniolo, C. 1994: Defect peptide chemistry: perturbations in the structure of a homopentapeptide induced by a guest residue interrupting side-chain regularity. Biopolymers 34(10): 1409-1418
Malkin, A.J.; Kuznetsov, Y.G.; Mcpherson, A. 1996: Defect structure of macromolecular crystals. Journal of Structural Biology 117(2): 124-137
Troncone, R.; Caputo, N.; Zibella, A.; Russo, R.; Rossi, M.; Gianfrani, C.; Stern, M.; Wieser, H.; Auricchio, S. 1996: Defective 'gut processing' of gliadin in mice with graft-versus-host enteropathy. International Archives of Allergy and Immunology 109(1): 44-49
Shigetomi, S.; Kuchel, O. 1993: Defective 3,4-dihydroxyphenylalanine decarboxylation to dopamine in hydralazine-treated hypertensive patients may be pyridoxine remediable. American Journal of Hypertension 6(1): 33-40
Marcil, J.; Anand-Srivastava, M.B. 1995: Defective ANF-R2/ANP-C receptor-mediated signalling in hypertension. Molecular and Cellular Biochemistry 149-150: 223-231
Montserrat, C.; Merten, M.; Figarella, C. 1996: Defective ATP-dependent mucin secretion by cystic fibrosis pancreatic epithelial cells. Febs Letters 393(2-3): 264-268
Su, G.H.; Chen, H.M.; Muthusamy, N.; Garrett-Sinha, L.A.; Baunoch, D.; Tenen, D.G.; Simon, M.C. 1997: Defective B cell receptor-mediated responses in mice lacking the Ets protein, Spi-B. EMBO Journal 16(23): 7118-7129
García-Cózar, F.J.; Molina, I.J.; Cuadrado, M.J.; Marubayashi, M.; Peña, J.; Santamaría, M. 1996: Defective B7 expression on antigen-presenting cells underlying T cell activation abnormalities in systemic lupus erythematosus (SLE) patients. Clinical and Experimental Immunology 104(1): 72-79
Takahashi, O.; Oishi, S.; Watanabe, M.F. 1995: Defective Blood Coagulation is not Causative of Hepatic Haemorrhage Induced by Microcystin-LR. Pharmacology and Toxicology 76(4): 250-254
Zielen, S.; Dengler, T.J.; Bauscher, P.; Meuer, S.C. 1994: Defective CD2 T cell pathway activation in common variable immunodeficiency (CVID). Clinical and Experimental Immunology 96(2): 253-259
Kovacs, B.; Vassilopoulos, D.; Vogelgesang, S.A.; Tsokos, G.C. 1996: Defective CD3-mediated cell death in activated T cells from patients with systemic lupus erythematosus: role of decreased intracellular TNF-alpha. Clinical Immunology and Immunopathology 81(3): 293-302
Fitzpatrick, E.A.; Kaplan, A.M.; Cohen, D.A. 1996: Defective CD4+ T cell signaling in murine AIDS: uncoupling of the T cell receptor complex from PIP2 hydrolysis. Cellular Immunology 167(2): 176-187
Whitehead, C.C.; Rennie, J.S.; McCormack, H.A.; Hocking, P.M. 1993: Defective Down syndrome in chicks is not caused by riboflavin deficiency in breeders. British Poultry Science 34(3): 619-623
Chatziantoniou, C.; Ruan, X.; Arendshorst, W.J. 1995: Defective G protein activation of the cAMP pathway in rat kidney during genetic hypertension. Proceedings of the National Academy of Sciences of the United States of America 92(7): 2924-2928
Paules, R.S.; Levedakou, E.N.; Wilson, S.J.; Innes, C.L.; Rhodes, N.; Tlsty, T.D.; Galloway, D.A.; Donehower, L.A.; Tainsky, M.A.; Kaufmann, W.K. 1995: Defective G2 checkpoint function in cells from individuals with familial cancer syndromes. Cancer Research 55(8): 1763-1773
Pincheira, J.; Rodriguez, M.; Bravo, M.; Navarrete, M.H.; Lopez-Saez, J.F. 1994: Defective G2 repair in Down syndrome: Effect of caffeine, adenosine and niacinamide in control and X-ray irradiated lymphocytes. Clinical Genetics 45(1): 25-31
Parkkonen, P.; Hyoty, H.; Huupponen, T.; Leinikki, P.; Tuomilehto Wolf, E.; Knip, M.; Group, T.C.ildhood Diabetes, I.F.nland Study 1993: Defective HLA class II expression in monocytes of type 1 diabetic patients. Apmis 101(5): 395-402
Jensen, S.; Cavarec, L.; Gassama, M.P.; Heidmann, T. 1995: Defective I elements introduced into Drosophila as transgenes can regulate reactivity and prevent I-R hybrid dysgenesis. Molecular and General Genetics: Mgg 248(4): 381-390
Koike, M.; Kikuchi, Y.; Tominaga, A.; Takaki, S.; Akagi, K.; Miyazaki, J.; Yamamura, K.; Takatsu, K. 1995: Defective IL-5-receptor-mediated signaling in B cells of X-linked immunodeficient mice. International Immunology 7(1): 21-30
Weimer, R.; Zipperle, S.; Daniel, V.; Zimmermann, R.; Opelz, G. 1993: Defective IL-6 secretion in HIV-infected haemophilia patients. Clinical and Experimental Immunology 91(2): 249-256
Yoshimoto, T.; Bendelac, A.; Hu-Li, J.; Paul, W.E. 1995: Defective IgE production by SJL mice is linked to the absence of CD4+, NK1.1+ T cells that promptly produce interleukin 4. Proceedings of the National Academy of Sciences of the United States of America 92(25): 11931-11934
Unsworth, D.J.; Rowen, D.; Carne, C.; Sonnex, C.; Baglin, T.; Brown, D.L. 1993: Defective IgG2 response to Pneumovax in HIV seropositive patients. Genitourinary Medicine 69(5): 373-376
Shafman, T.D.; Saleem, A.; Kyriakis, J.; Weichselbaum, R.; Kharbanda, S.; Kufe, D.W. 1995: Defective induction of stress-activated protein kinase activity in ataxia-telangiectasia cells exposed to ionizing radiation. Cancer Research 55(15): 3242-3245
Battezzati, A.; Terruzzi, I.; Perseghin, G.; Bianchi, E.; Di Carlo, V.; Pozza, G.; Luzi, L. 1995: Defective insulin action on protein and glucose metabolism during chronic hyperinsulinemia in subjects with benign insulinoma. Diabetes 44(7): 837-844
Taddei, S.; Virdis, A.; Mattei, P.; Ghiadoni, L.; Sudano, I.; Salvetti, A. 1996: Defective L-arginine-nitric oxide pathway in offspring of essential hypertensive patients. Circulation 94(6): 1298-1303
Takeda, K.; Tsutsui, H.; Yoshimoto, T.; Adachi, O.; Yoshida, N.; Kishimoto, T.; Okamura, H.; Nakanishi, K.; Akira, S. 1998: Defective NK cell activity and Th1 response in IL-18-deficient mice. Immunity 8(3): 383-390
Reed, D.S.; Gibson, J.B. 1993: Defective P element insertions affect the expression of sn-glycerol-3-phosphate dehydrogenase alleles in natural populations of Drosophila melanogaster. Proceedings. Biological Sciences 251(1330): 39-45
Neumann, B.; Luz, A.; Pfeffer, K.; Holzmann, B. 1996: Defective Peyer's patch organogenesis in mice lacking the 55-kD receptor for tumor necrosis factor. Journal of Experimental Medicine 184(1): 259-264
Frevert, C.W.; Warner, A.E.; Kobzik, L. 1994: Defective pulmonary recruitment of neutrophils in a rat model of endotoxemia. American Journal of Respiratory Cell and Molecular Biology 11(6): 716-723
Piriev, N.I.; Shih, J.M.; Farber, D.B. 1998: Defective RNA splicing resulting from a mutation in the cyclic guanosine monophosphate-phosphodiesterase beta-subunit gene. IOVS Investigative Ophthalmology and Visual Science 39(3): 463-470
Ronfort, C.; Girod, A.; Cosset, F.L.; Legras, C.; Nigon, V.M.; Chebloune, Y.; Verdier, G. 1995: Defective retroviral endogenous RNA is efficiently transmitted by infectious particles produced on an avian retroviral vector packaging cell line. Virology 207(1): 271-275
Brunner, F.; Mouton, R.; Lochner, A.; Opie, L.H. 1995: Defective stretch-induced release of atrial natriuretic peptide from aging hypertensive rat heart: possible role of phosphatidylinositol pathway. Journal of Cardiovascular Pharmacology 25(1): 168-176
Arpaia, E.; Shahar, M.; Dadi, H.; Cohen, A.; Roifman, C.M. 1994: Defective T cell receptor signaling and CD8+ thymic selection in humans lacking Zap-70 kinase. Cell 76(5): 947-958
Kanagawa, O.; Wiebenga, M.E.; Vaupel, B.A. 1993: Defective T cell receptor-mediated signaling and differential induction of T cell functions by murine AIDS virus superantigen. Journal of Immunology 150(5): 1865-1872
De Maria, R.; Todaro, M.; Stassi, G.; Di Blasi, F.; Giordano, M.; Galluzzo, A.; Giordano, C. 1994: Defective T cell receptor/CD3 complex signaling in human type i diabetes. European Journal of Immunology 24(4): 999-1002
Yasutomo, K.; Maeda, K.; Nagata, S.; Nagasawa, H.; Okada, K.; Good, R.A.; Kuroda, Y.; Himeno, K. 1994: Defective T cells from gld mice play a pivotal role in development of Thy-1.2+B220+ cells and autoimmunity. Journal of Immunology 153(12): 5855-5864
Candéias, S.; Peschon, J.J.; Muegge, K.; Durum, S.K. 1997: Defective T-cell receptor gamma gene rearrangement in interleukin-7 receptor knockout mice. Immunology Letters 57(1-3): 9-14
Fischer, K.D.; Zmuidzinas, A.; Gardner, S.; Barbacid, M.; Bernstein, A.; Guidos, C. 1995: Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+CD8+ thymocytes. Nature (London) 374(6521): 474-477
Møller, J.; Hofmann, B.; Jacobsen, N.; Ryder, L.P.; Platz, P.; Dickmeiss, E.; Svejgaard, A. 1993: Defective T-cell stimulatory pathways in patients after allogeneic bone marrow transplantation (BMT) in man. Apmis: Acta Pathologica Microbiologica et Immunologica Scandinavica 101(6): 480-486
Fischer, M.B.; Hauber, I.; Födinger, M.; Wolf, H.M.; Thon, V.; Donath, P.; Eibl, M.M.; Knobler, R.M. 1995: Defective TCR surface expression associated with impaired TCR beta-chain assembly in a patient with cutaneous T-cell lymphoma. Journal of Investigative Dermatology 104(4): 537-540
Barnden, M.J.; Allison, J.; Heath, W.R.; Carbone, F.R. 1998: Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements. Immunology and Cell Biology 76(1): 34-40
Migita, K.; Eguchi, K.; Kawabe, Y.; Tsukada, T.; Ichinose, Y.; Nagataki, S.; Ochi, A. 1995: Defective TCR-mediated signaling in anergic T cells. Journal of Immunology 155(11): 5083-5087
Michael, N.L.; Chang, G.; d'Arcy, L.A.; Ehrenberg, P.K.; Mariani, R.; Busch, M.P.; Birx, D.L.; Schwartz, D.H. 1995: Defective accessory genes in a human immunodeficiency virus type 1-infected long-term survivor lacking recoverable virus. Journal of Virology 69(7): 4228-4236
Altan, N.; Chen, Y.; Schindler, M.; Simon, S.M. 1998: Defective acidification in human breast tumor cells and implications for chemotherapy. Journal of Experimental Medicine 187(10): 1583-1598
Barasch, J.; al-Awqati, Q. 1993: Defective acidification of the biosynthetic pathway in cystic fibrosis. Journal of Cell Science. Supplement 17: 229-233
Facchetti, F.; Blanzuoli, L.; Vermi, W.; Notarangelo, L.D.; Giliani, S.; Fiorini, M.; Fasth, A.; Stewart, D.M.; Nelson, D.L. 1998: Defective actin polymerization in EBV-transformed B-cell lines from patients with the Wiskott-Aldrich syndrome. Journal of Pathology 185(1): 99-107
Gallego, M.D.; Santamaría, M.; Peña, J.; Molina, I.J. 1997: Defective actin reorganization and polymerization of Wiskott-Aldrich T cells in response to CD3-mediated stimulation. Blood 90(8): 3089-3097
Pignata, C.; Sanghera, J.S.; Soiffer, R.J.; Chartier, S.; Eder, M.; Pelech, S.L.; Ritz, J. 1996: Defective activation of mitogen-activated protein kinase after allogeneic bone marrow transplantation. Blood 88(6): 2334-2341
Chabior, M.; Kabata, J.; Wierzba, J.; Ploszynska, A.; Balcerska, A. 1995: Defective activation of polymorphonuclear neutrophil locomotion (PMN) after splenectomy in children with hereditary spherocytosis. Paediatrie und Paedologie 30(5): 95-98
Bianchi, R.; Veronese, A.; Marini, P.; Mennini, T.; Fiori, M.G. 1994: Defective activity of Na+,K(+)-ATPase in peripheral nerve of diabetic rats is independent of the axonal transport of the enzyme. Neuroscience Letters 178(1): 127-130
Fauvel-Lafève, F.; Tabaka, V.; Caen, J.P.; Legrand, Y.J. 1993: Defective adhesion of blood platelets to vascular microfibrils in the Bernard-Soulier syndrome. Blood 82(7): 1985-1988
Tanaka, T.; Yoshida, N.; Kishimoto, T.; Akira, S. 1997: Defective adipocyte differentiation in mice lacking the C/EBPbeta and/or C/EBPdelta gene. EMBO Journal 16(24): 7432-7443
Laffi, G.; Cinotti, S.; Filimberti, E.; Ciabattoni, G.; Caporale, R.; Marra, F.; Melani, L.; Grossi, A.; Carloni, V.; Gentilini, P. 1996: Defective aggregation in cirrhosis is independent of in vivo platelet activation. Journal of Hepatology 24(4): 436-443
Yu, R.C.; Morris, J.F.; Pritchard, J.; Chu, T.C. 1992: Defective alloantigen-presenting capacity of 'Langerhans cell histiocytosis cells'. Archives of Disease in Childhood 67(11): 1370-1372
Terstappen, L.W.; Nguyen, M.; Huang, S.; Lazarus, H.M.; Medof, M.E. 1993: Defective and normal haematopoietic stem cells in paroxysmal nocturnal haemoglobinuria. British Journal of Haematology 84(3): 504-514
Fivush, B.A.; Case, B.; Warady, B.A.; Lederman, H. 1993: Defective antibody response to Hemophilus influenzae type b immunization in children receiving peritoneal dialysis. Pediatric Nephrology 7(5): 548-550
Obaro, S.K.; Henderson, D.C.; Monteil, M.A. 1996: Defective antibody-mediated opsonisation of S. pneumoniae in high risk patients detected by flow cytometry. Immunology Letters 49(1-2): 83-89
Gercken, J.; Pryjma, J.; Ernst, M.; Flad, H.D. 1994: Defective antigen presentation by Mycobacterium tuberculosis-infected monocytes. Infection and Immunity 62(8): 3472-3478
Knight, R.A.; Kollnberger, S.; Madden, B.; Yacoub, M.; Hodson, M.E. 1997: Defective antigen presentation by lavage cells from terminal patients with cystic fibrosis. Clinical and Experimental Immunology 107(3): 542-547
Stachowski, J.; Barth, C.; Pollok, M.; Michałkiewicz, J.; Madaliński, K.; Maciejewski, J.; Baldamis, C.A. 1995: Defective antigen presentation by monocytes in ESRD patients not responding to hepatitis B vaccination: impaired HBsAg internalization and expression of ICAM-1 and HLA-DR/Ia molecules. Mediators of Inflammation 4(1): 49-54
D'Souza, S.; Levin, M.; Faith, A.; Yssel, H.; Bennett, B.; Lake, R.A.; Brown, I.N.; Lamb, J.R. 1996: Defective antigen processing associated with familial disseminated mycobacteriosis. Clinical and Experimental Immunology 103(1): 35-39
Short, S.; Merkel, B.J.; Caffrey, R.; McCoy, K.L. 1996: Defective antigen processing correlates with a low level of intracellular glutathione. European Journal of Immunology 26(12): 3015-3020
Ameratunga, R.; Lederman, H.M.; Sullivan, K.E.; Ochs, H.D.; Seyama, K.; French, J.K.; Prestidge, R.; Marbrook, J.; Fanslow, W.C.; Winkelstein, J.A. 1997: Defective antigen-induced lymphocyte proliferation in the X-linked hyper-IgM syndrome. Journal of Pediatrics 131(1 Pt 1): 147-150
Tsokos, G.C.; Kovacs, B.; Sfikakis, P.P.; Theocharis, S.; Vogelgesang, S.; Via, C.S. 1996: Defective antigen-presenting cell function in patients with systemic lupus erythematosus. Arthritis and Rheumatism 39(4): 600-609
Anderson, C.C.; Cairns, E.; Rudofsky, U.H.; Sinclair, N.R. 1995: Defective antigen-receptor-mediated regulation of immunoglobulin production in B cells from autoimmune strains of mice. Cellular Immunology 164(1): 141-149
Sanders, L.A.; Rijkers, G.T.; Kuis, W.; Tenbergen-Meekes, A.J.; de Graeff-Meeder, B.R.; Hiemstra, I.; Zegers, B.J. 1993: Defective antipneumococcal polysaccharide antibody response in children with recurrent respiratory tract infections. Journal of Allergy and Clinical Immunology 91(1 Pt 1): 110-119
Tamarappoo, B.K.; Verkman, A.S. 1998: Defective aquaporin-2 trafficking in nephrogenic diabetes insipidus and correction by chemical chaperones. Journal of Clinical Investigation 101(10): 2257-2267
Fallon, R.J.; Danaher, M.; Saylors, R.L.; Saxena, A. 1994: Defective asialoglycoprotein receptor endocytosis mediated by tyrosine kinase inhibitors. Requirement for a tyrosine in the receptor internalization signal. Journal of Biological Chemistry 269(15): 11011-11017
Yuan, J.; Rubin, E.; Aljurf, M.; Ma, L.; Schrier, S.L. 1994: Defective assembly of membrane proteins in erythroid precursors of beta-thalassemic mice. Blood 84(2): 632-637
Iwata, Y.; Nakamura, H.; Mizuno, Y.; Yoshida, M.; Ozawa, E.; Shigekawa, M. 1993: Defective association of dystrophin with sarcolemmal glycoproteins in the cardiomyopathic hamster heart. Febs Letters 329(1-2): 227-231
Hagedorn, H.; Schreiner, M.; Wiest, I.; Tübel, J.; Schleicher, E.D.; Nerlich, A.G. 1998: Defective basement membrane in laryngeal carcinomas with heterogeneous loss of distinct components. Human Pathology 29(5): 447-454
Davis, W.; Chowrimootoo, G.F.; Seymour, C.A. 1996: Defective biliary copper excretion in Wilson's disease: The role of caeruloplasmin. European Journal of Clinical Investigation 26(10): 893-901
Wang, S.; Kussie, P.; Deng, L.; Tall, A. 1995: Defective binding of neutral lipids by a carboxyl-terminal deletion mutant of cholesteryl ester transfer protein. Evidence for a carboxyl-terminal cholesteryl ester binding site essential for neutral lipid transfer activity. Journal of Biological Chemistry 270(2): 612-618
Helander, I.M.; Lindner, B.; Seydel, U.; Vaara, M. 1993: Defective biosynthesis of the lipid A component of temperature-sensitive firA (omsA) mutant of Escherichia coli. European Journal of Biochemistry 212(2): 363-369
Levi, G.; Topilko, P.; Schneider-Maunoury, S.; Lasagna, M.; Mantero, S.; Cancedda, R.; Charnay, P. 1996: Defective bone formation in Krox-20 mutant mice. Development 122(1): 113-120
Barbiroli, B.; Montagna, P.; Cortelli, P.; Iotti, S.; Lodi, R.; Barboni, P.; Monari, L.; Lugaresi, E.; Frassineti, C.; Zaniol, P. 1995: Defective brain and muscle energy metabolism shown by in vivo 31P magnetic resonance spectroscopy in nonaffected carriers of 11778 mtDNA mutation. Neurology 45(7): 1364-1369
Barbiroli, B.; Montagna, P.; Martinelli, P.; Lodi, R.; Iotti, S.; Cortelli, P.; Funicello, R.; Zaniol, P. 1993: Defective brain energy metabolism shown by in vivo phosphorus-31 MR spectroscopy in 28 patients with mitochondrial cytopathies. Journal of Cerebral Blood Flow and Metabolism 13(3): 469-474
Winter, J.B.; Prop, J.; Groen, M.; Petersen, A.H.; Uyama, T.; Meedendorp, B.; Wildevuur, C.R. 1995: Defective bronchus-associated lymphoid tissue in long-term surviving rat lung allografts. American Journal of Respiratory and Critical Care Medicine 152(4 Part 1): 1367-1373
Morra, L.; Moccia, F.; Mazzarello, G.P.; Bessone, G.; Del Nero, E.; Ponassi, G.A. 1994: Defective burst-promoting activity of T lymphocytes from anemic and nonanemic elderly people. Annals of Hematology 68(2): 67-71
Svoboda, D.L.; Briley, L.P.; Vos, J.M. 1998: Defective bypass replication of a leading strand cyclobutane thymine dimer in xeroderma pigmentosum variant cell extracts. Cancer Research 58(11): 2445-2448
Stefanini, G.F.; Castelli, E.; Foschi, F.G.; Terzi, A.; Biagi, P.L.; Bordoni, A.; Celadon, M.; Hrelia, S. 1996: Defective calcium increase and inositol phosphate production in anti-CD3-stimulated lymphocytes of alcoholics without progressive liver disease. Alcoholism Clinical and Experimental Research 20(3): 523-527
Oehninger, S.; Blackmore, P.; Morshedi, M.; Sueldo, C.; Acosta, A.A.; Alexander, N.J. 1994: Defective calcium influx and acrosome reaction (spontaneous and progesterone-induced) in spermatozoa of infertile men with severe teratozoospermia. Fertility and Sterility 61(2): 349-354
Shinobu, N.; Kobayashi, M.; Wang, J.; Li, Y.Q.; Imai, K.; Matsuno, K.; Hosokawa, M. 1996: Defective calcium influx in rat myelomonocytic leukemia cells which are resistant to differentiation-inducing effects of lipid a. Experimental Cell Research 226(1): 191-196
Michel, F.; Merle-Béral, H.; Legac, E.; Michel, A.; Debré, P.; Bismuth, G. 1993: Defective calcium response in B-chronic lymphocytic leukemia cells. Alteration of early protein tyrosine phosphorylation and of the mechanism responsible for cell calcium influx. Journal of Immunology 150(8 Pt 1): 3624-3633
Schallreuter-Wood, K.U.; Pittelkow, M.R.; Swanson, N.N. 1996: Defective calcium transport in vitiliginous melanocytes. Archives of Dermatological Research 288(1): 11-13
Kondo, N.; Inoue, R.; Yano, M.; Hayashi, T.; Miwa, Y.; Kasahara, K.; Yamasaki, M.; Utsumi, M.; Shinbara, M.; Orii, T. 1993: Defective calcium-dependent signal transduction in B lymphocytes of a certain common variable immunodeficiency. Experimental and Clinical Immunogenetics 10(1): 16-20
Kondo, N.; Inoue, R.; Nishimura, S.; Kasahara, K.; Kameyama, T.; Miwa, Y.; Lorenzo, P.R.; Orii, T. 1993: Defective calcium-dependent signal transduction in T lymphocytes of ataxia-telangiectasia. Scandinavian Journal of Immunology 38(1): 45-48
Mirshahi, S.S.; Lounes, K.C.; Lu, H.; Pujade-Lauraine, E.; Mishal, Z.; Bénard, J.; Bernadou, A.; Soria, C.; Soria, J. 1997: Defective cell migration in an ovarian cancer cell line is associated with impaired urokinase-induced tyrosine phosphorylation. Febs Letters 411(2-3): 322-326
Daniel, M.A.; McDonald, G.; Offenbacher, S.; Van Dyke, T.E. 1993: Defective chemotaxis and calcium response in localized juvenile periodontitis neutrophils. Journal of Periodontology 64(7): 617-621
Tint, G.S.; Irons, M.; Elias, E.R.; Batta, A.K.; Frieden, R.; Chen, T.S.; Salen, G. 1994: Defective cholesterol biosynthesis associated with the Smith-Lemli-Opitz syndrome. New England Journal of Medicine 330(2): 107-113
Soliman, A.T.; Mohsin, N.; al Hasani, M.; Elbualy, M. 1995: Defective clonidine-induced growth hormone secretion and normal thyroid and adrenal functions in prepubertal children with chronic renal insufficiency (CRF). Journal of Tropical Pediatrics 41(4): 221-224
Mencacci, A.; Cenci, E.; Del Sero, G.; Fè d'Ostiani, C.; Mosci, P.; Montagnoli, C.; Bacci, A.; Bistoni, F.; Quesniaux, V.F.; Ryffel, B.; Romani, L. 1998: Defective co-stimulation and impaired Th1 development in tumor necrosis factor/lymphotoxin-alpha double-deficient mice infected with Candida albicans. International Immunology 10(1): 37-48
Honda, A.; Tint, G.S.; Salen, G.; Batta, A.K.; Chen, T.S.; Shefer, S. 1995: Defective conversion of 7-dehydrocholesterol to cholesterol in cultured skin fibroblasts from Smith-Lemli-Opitz syndrome homozygotes. Journal of Lipid Research 36(7): 1595-1601
Kojimahara, N.; Nakabayashi, H.; Shikata, T.; Esumi, M. 1995: Defective copper binding to apo-ceruloplasmin in a rat model and patients with Wilson's disease. Liver 15(3): 135-142
Swain, M.G.; Maric, M. 1995: Defective corticotropin-releasing hormone mediated neuroendocrine and behavioral responses in cholestatic rats: Implications for cholestatic liver disease-related sickness behaviors. Hepatology 22(5): 1560-1564
Kluijtmans, L.A.; Boers, G.H.; Stevens, E.M.; Renier, W.O.; Kraus, J.P.; Trijbels, F.J.; van den Heuvel, L.P.; Blom, H.J. 1996: Defective cystathionine beta-synthase regulation by S-adenosylmethionine in a partially pyridoxine responsive homocystinuria patient. Journal of Clinical Investigation 98(2): 285-289
Pirenne-Ansart, H.; Paillard, F.; De Groote, D.; Eljaafari, A.; Le Gac, S.; Blot, P.; Franchimont, P.; Vaquero, C.; Sterkers, G. 1995: Defective cytokine expression but adult-type T-cell receptor, CD8, and p56lck modulation in CD3- or CD2-activated T cells from neonates. Pediatric Research 37(1): 64-69
Guillaume, T.; Sekhavat, M.; Rubinstein, D.B.; Hamdan, O.; Leblanc, P.; Symann, M.L. 1994: Defective cytokine production following autologous stem cell transplantation for solid tumors and hematologic malignancies regardless of bone marrow or peripheral origin and lack of evidence for a role for interleukin-10 in delayed immune reconstitution. Cancer Research 54(14): 3800-3807
Homma, M.; van Breda Vriesman, P.J.; Damoiseaux, J.G. 1997: Defective de novo thymocyte maturation in cyclosporin A (CsA)-induced autoimmunity: Expression of costimulatory and activation molecules. Clinical and Experimental Immunology 110(1): 79-85
Mayatepek, E.; Tiepelmann, B. 1996: Defective degradation of leukotrienes in peroxisomal-deficient human hepatocytes. Biochemical and Biophysical Research Communications 227(1): 131-134
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Lattanzio, G.; Libert, C.; Aquilina, M.; Cappelletti, M.; Ciliberto, G.; Musiani, P.; Poli, V. 1997: Defective development of pristane-oil-induced plasmacytomas in interleukin-6-deficient BALB/c mice. American Journal of Pathology 151(3): 689-696
Varma, P.V.; Frunchak, Y.N.; Evanson, J.E.; Milos, N.C. 1994: Defective development of the craniofacial/digestive complex of Xenopus laevis after treatment with endogenous galactoside-binding lectin or its hapten inhibitor thiodigalactoside. Journal of Craniofacial Genetics and Developmental Biology 14(3): 177-191
Kwee, L.; Baldwin, H.S.; Shen, H.M.; Stewart, C.L.; Buck, C.; Buck, C.A.; Labow, M.A. 1995: Defective development of the embryonic and extraembryonic circulatory systems in vascular cell adhesion molecule (VCAM-1) deficient mice. Development 121(2): 489-503
Hough, M.R.; Takei, F.; Humphries, R.K.; Kay, R. 1994: Defective development of thymocytes overexpressing the costimulatory molecule, heat-stable antigen. Journal of Experimental Medicine 179(1): 177-184
Schneppenheim, R.; Brassard, J.; Krey, S.; Budde, U.; Kunicki, T.J.; Holmberg, L.; Ware, J.; Ruggeri, Z.M. 1996: Defective dimerization of von Willebrand factor subunits due to a Cys fwdarw Arg mutation in type IID von Willebrand disease. Proceedings of the National Academy of Sciences of the United States of America 93(8): 3581-3586
Zeitlinger, J.; Kockel, L.; Peverali, F.A.; Jackson, D.B.; Mlodzik, M.; Bohmann, D. 1997: Defective dorsal closure and loss of epidermal decapentaplegic expression in Drosophila fos mutants. EMBO Journal 16(24): 7393-7401
Fernández-Gutiérrez, B.; de Miguel, S.; Morado, C.; Hernández-García, C.; Bañares, A.; Jover, J.A. 1998: Defective early T and T-dependent B cell activation in systemic lupus erythematosus. Lupus 7(5): 314-322
Nilsson Ekdahl, K.; Lööf, L.; Ahrenstedt, O.; Nilsson, U.R.; Nilsson, B. 1997: Defective elimination of C3b/iC3b-coated autologous erythrocytes in patients with primary biliary cirrhosis, alcoholic cirrhosis, and ulcerative colitis. Journal of Laboratory and Clinical Medicine 130(3): 285-292
Wanke, T.; Auinger, M.; Formanek, D.; Merkle, M.; Lahrmann, H.; Ogris, E.; Zwick, H.; Irsigler, K. 1996: Defective endogenous opioid response to exercise in type I diabetic patients. Metabolism, Clinical and Experimental 45(2): 137-142
Cailes, J.; Winter, S.; du Bois, R.M.; Evans, T.W. 1998: Defective endothelially mediated pulmonary vasodilation in systemic sclerosis. Chest 114(1): 178-184
Verma, S.; Bhanot, S.; Yao, L.; Mcneill, J.H. 1996: Defective endothelium-dependent relaxation in fructose-hypertensive rats. American Journal of Hypertension 9(4 Pt 1): 370-376
McNamee, C.J.; Kappagoda, C.T.; Kunjara, R.; Russell, J.C. 1994: Defective endothelium-dependent relaxation in the JCR:LA-corpulent rat. Circulation Research 74(6): 1126-1132
Liu, L.H.; Paul, R.J.; Sutliff, R.L.; Miller, M.L.; Lorenz, J.N.; Pun, R.Y.; Duffy, J.J.; Doetschman, T.; Kimura, Y.; MacLennan, D.H.; Hoying, J.B.; Shull, G.E. 1997: Defective endothelium-dependent relaxation of vascular smooth muscle and endothelial cell Ca2+ signaling in mice lacking sarco(endo)plasmic reticulum Ca2+-ATPase isoform 3. Journal of Biological Chemistry 272(48): 30538-30545
Wang, J.; Seyedi, N.; Xu, X.B.; Wolin, M.S.; Hintze, T.H. 1994: Defective endothelium-mediated control of coronary circulation in conscious dogs after heart failure. American Journal of Physiology 266(2 Pt 2): H670-H680
Subramanian, G.; LeBlanc, R.A.; Wardley, R.C.; Fuller, A.O. 1995: Defective entry of herpes simplex virus types 1 and 2 into porcine cells and lack of infection in infant pigs indicate species tropism. Journal of General Virology 76: 2375-2379
Berry, R.M.; Nowak, M.A. 1994: Defective escape mutants of HIV. Journal of Theoretical Biology 171(4): 387-395
Gómez, A.M.; Valdivia, H.H.; Cheng, H.; Lederer, M.R.; Santana, L.F.; Cannell, M.B.; McCune, S.A.; Altschuld, R.A.; Lederer, W.J. 1997: Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure. Science 276(5313): 800-806
Guigueno, A.; Belin, P.; Boquet, P.L. 1997: Defective export in Escherichia coli caused by DsbA'-PhoA hybrid proteins whose DsbA' domain cannot fold into a conformation resistant to periplasmic proteases. Journal of Bacteriology 179(10): 3260-3269
Cho, H.; Cronan, J.E. 1995: Defective export of a periplasmic enzyme disrupts regulation of fatty acid synthesis. Journal of Biological Chemistry 270(9): 4216-4219
Simon, H.U.; Higgins, E.A.; Demetriou, M.; Datti, A.; Siminovitch, K.A.; Dennis, J.W. 1993: Defective expression of CD23 and autocrine growth-stimulation in Epstein-Barr virus (EBV)-transformed B cells from patients with Wiskott-Aldrich syndrome (WAS). Clinical and Experimental Immunology 91(1): 43-49
Stassi, G.; Todaro, M.; De Maria, R.; Candore, G.; Cigna, D.; Caruso, C.; Galluzzo, A.; Giordano, C. 1997: Defective expression of CD95 (FAS/APO-1) molecule suggests apoptosis impairment of T and B cells in HLA-B8, DR3-positive individuals. Human Immunology 55(1): 39-45
Spinozzi, F.; Fizzotti, M.; Agea, E.; Piattoni, S.; Droetto, S.; Russano, A.; Forenza, N.; Bassotti, G.; Grignani, F.; Bertotto, A. 1998: Defective expression of Fas messenger RNA and Fas receptor on pulmonary T cells from patients with asthma. Annals of Internal Medicine 128(5): 363-369
Plebani, A.; Monafo, V.; Cattaneo, R.; Carella, G.; Brugnoni, D.; Facchetti, F.; Battocchio, S.; Meini, A.; Notarangelo, L.D.; Duse, M.; Ugazio, A.G. 1996: Defective expression of HLA class I and CD1a molecules in boy with Marfan-like phenotype and deep skin ulcers. Journal of the American Academy of Dermatology 35(5 Pt 2): 814-818
Nouri, A.M.; Hussain, R.F.; Dos Santos, A.V.; Oliver, R.T. 1996: Defective expression of adhesion molecules on human bladder tumour and human tumour cell lines. Urologia Internationalis 56(1): 6-12
Jing, Y.; Zhang, J.; Bleiweiss, I.J.; Waxman, S.; Zelent, A.; Mira-Y-Lopez, R. 1996: Defective expression of cellular retinol binding protein type I and retinoic acid receptors alpha2, beta2, and gamma2 in human breast cancer cells. FASEB Journal 10(9): 1064-1070
Irizar, A.; Barnett, C.R.; Flatt, P.R.; Ioannides, C. 1995: Defective expression of cytochrome P450 proteins in the liver of the genetically obese Zucker rat. European Journal of Pharmacology 293(4): 385-393
Castigli, E.; Irani, A.M.; Geha, R.S.; Chatila, T. 1995: Defective expression of early activation genes in cartilage-hair hypoplasia (CHH) with severe combined immunodeficiency (SCID). Clinical and Experimental Immunology 102(1): 6-10
Toy, L.S.; Yio, X.Y.; Lin, A.; Honig, S.; Mayer, L. 1997: Defective expression of gp180, a novel CD8 ligand on intestinal epithelial cells, in inflammatory bowel disease. Journal of Clinical Investigation 100(8): 2062-2071
Dirksen, U.; Hattenhorst, U.; Schneider, P.; Schroten, H.; Göbel, U.; Böcking, A.; Müller, K.M.; Murray, R.; Burdach, S. 1998: Defective expression of granulocyte-macrophage colony-stimulating factor/interleukin-3/interleukin-5 receptor common beta chain in children with acute myeloid leukemia associated with respiratory failure. Blood 92(4): 1097-1103
Urbani, F.; Maleci, A.; La Sala, A.; Lande, R.; Ausiello, C.M. 1995: Defective expression of interferon-gamma, granulocyte-macrophage colony-stimulating factor, tumor necrosis factor alpha, and interleukin-6 in activated peripheral blood lymphocytes from glioma patients. Journal of Interferon and Cytokine Research: the Official Journal of the International Society for Interferon and Cytokine Research 15(5): 421-429
Goldman, F.D.; Ballas, Z.K.; Schutte, B.C.; Kemp, J.; Hollenback, C.; Noraz, N.; Taylor, N. 1998: Defective expression of p56lck in an infant with severe combined immunodeficiency. Journal of Clinical Investigation 102(2): 421-429
Gache, Y.; Chavanas, S.; Lacour, J.P.; Wiche, G.; Owaribe, K.; Meneguzzi, G.; Ortonne, J.P. 1996: Defective expression of plectin/HD1 in epidermolysis bullosa simplex with muscular dystrophy. Journal of Clinical Investigation 97(10): 2289-2298
Fuleihan, R.; Ramesh, N.; Loh, R.; Jabara, H.; Rosen, R.S.; Chatila, T.; Fu, S.M.; Stamenkovic, I.; Geha, R.S. 1993: Defective expression of the CD40 ligand in X chromosome-linked immunoglobulin deficiency with normal or elevated IgM. Proceedings of the National Academy of Sciences of the United States of America 90(6): 2170-2173
Davis, T.W.; Wilson-Van Patten, C.; Meyers, M.; Kunugi, K.A.; Cuthill, S.; Reznikoff, C.; Garces, C.; Boland, C.R.; Kinsella, T.J.; Fishel, R.; Boothman, D.A. 1998: Defective expression of the DNA mismatch repair protein, MLH1, alters G2-M cell cycle checkpoint arrest following ionizing radiation. Cancer Research 58(4): 767-778
Giordano, C.; De Maria, R.; Stassi, G.; Todaro, M.; Richiusa, P.; Giordano, M.; Testi, R.; Galluzzo, A. 1995: Defective expression of the apoptosis-inducing CD95 (Fas/APO-1) molecule on T and B cells in IDDM. Diabetologia 38(12): 1449-1454
Richmond, J.E.; VanDeCarr, D.; Featherstone, D.E.; George, A.L.; Ruben, P.C. 1997: Defective fast inactivation recovery and deactivation account for sodium channel myotonia in the I1160V mutant. Biophysical Journal 73(4): 1896-1903
Hirose, H.; Lee, Y.H.; Inman, L.R.; Nagasawa, Y.; Johnson, J.H.; Unger, R.H. 1996: Defective fatty acid-mediated beta-cell compensation in Zucker diabetic fatty rats. Pathogenic implications for obesity-dependent diabetes. Journal of Biological Chemistry 271(10): 5633-5637
Killewich, L.A.; Macko, R.F.; Gardner, A.W.; Cox, K.; Lilly, M.P.; Flinn, W.R. 1997: Defective fibrinolysis occurs after infrainguinal reconstruction. Journal of Vascular Surgery 25(5): 858
Smith, J.J.; Karp, P.H.; Welsh, M.J. 1994: Defective fluid transport by cystic fibrosis airway epithelia. Journal of Clinical Investigation 93(3): 1307-1311
Zhang, B.; Peng, Z. 1996: Defective folding of mutant p16(INK4) proteins encoded by tumor-derived alleles. Journal of Biological Chemistry 271(46): 28734-28737
Willnow, T.E.; Hilpert, J.; Armstrong, S.A.; Rohlmann, A.; Hammer, R.E.; Burns, D.K.; Herz, J. 1996: Defective forebrain development in mice lacking gp330/megalin. Proceedings of the National Academy of Sciences of the United States of America 93(16): 8460-8464
Tesarik, J.; Mendoza, C. 1992: Defective function of a nongenomic progesterone receptor as a sole sperm anomaly in infertile patients. Fertility and Sterility 58(4): 793-797
Calzada, L.; Tellez, J. 1997: Defective function of membrane potential (psi) on sperm of infertile men. Archives of Andrology 38(2): 151-155
Pérez-Blas, M.; Martínez-Martín, B.; Carballido, J.; Hontoria, J.; Salazar, L.I.; Olivier, C.; Alvarez-Mon, M. 1995: Defective functional response to membrane stimuli in lymphocytes from patients with benign prostatic hyperplasia. Clinical and Experimental Immunology 101(3): 521-526
Segal, S. 1995: Defective galactosylation in galactosemia: Is low cell UDPgalactose an explanation?. European Journal of Pediatrics 154(7 Suppl 2): S65-S71
Charlwood, J.; Clayton, P.; Keir, G.; Mian, N.; Winchester, B. 1998: Defective galactosylation of serum transferrin in galactosemia. Glycobiology 8(4): 351-357
Slesinger, P.A.; Stoffel, M.; Jan, Y.N.; Jan, L.Y. 1997: Defective gamma-aminobutyric acid type B receptor-activated inwardly rectifying K+ currents in cerebellar granule cells isolated from weaver and Girk2 null mutant mice. Proceedings of the National Academy of Sciences of the United States of America 94(22): 12210-12217
Nakagawa, K. 1997: Defective generation of NK1.1+ T cells in aly/aly mice associated with thymic architecture. Hokkaido Journal of Medical Science 72(3): 285-295
Berg, R.J.; Ruven, H.J.; Sands, A.T.; de Gruijl, F.R.; Mullenders, L.H. 1998: Defective global genome repair in XPC mice is associated with skin cancer susceptibility but not with sensitivity to UVB induced erythema and edema. Journal of Investigative Dermatology 110(4): 405-409
Silbiger, S.R.; Cohen, A.J.; Fishman, J.B.; Stoff, J.S. 1994: Defective glomerular beta-adrenergic signal transmission in spontaneously diabetic rats. Journal of Laboratory and Clinical Medicine 124(2): 249-254
Kendall, D.M.; Teuscher, A.U.; Robertson, R.P. 1997: Defective glucagon secretion during sustained hypoglycemia following successful islet allo- and autotransplantation in humans. Diabetes 46(1): 23-27
Roe, M.W.; Philipson, L.H.; Frangakis, C.J.; Kuznetsov, A.; Mertz, R.J.; Lancaster, M.E.; Spencer, B.; Worley, J.F.; Dukes, I.D. 1994: Defective glucose-dependent endoplasmic reticulum Ca2+ sequestration in diabetic mouse islets of Langerhans. Journal of Biological Chemistry 269(28): 18279-18282
Lee, S.K.; Opara, E.C.; Surwit, R.S.; Feinglos, M.N.; Akwari, O.E. 1995: Defective glucose-stimulated insulin release from perifused islets of C57BL/6J mice. Pancreas 11(2): 206-211
Kudoh, S.; Redovan, C.; Rayman, P.; Edinger, M.; Tubbs, R.R.; Novick, A.; Finke, J.H.; Bukowski, R.M. 1997: Defective granzyme B gene expression and lytic response in T lymphocytes infiltrating human renal cell carcinoma. Journal of ImmunoTherapy 20(6): 479-487
Greaves, R.F.; Mocarski, E.S. 1998: Defective growth correlates with reduced accumulation of a viral DNA replication protein after low-multiplicity infection by a human cytomegalovirus ie1 mutant. Journal of Virology 72(1): 366-379
Soliman, A.T.; Darwish, A.; Alsalmi, I.; Asfour, M. 1996: Defective growth hormone secretion and hypogonadism in the new syndrome of congenital hypoparathyroidism, growth failure and dysmorphic features. Indian Journal of Pediatrics 63(5): 679-682
Soliman, A.T.; Rajab, A.; AlSalmi, I.; Darwish, A.; Asfour, M. 1996: Defective growth hormone secretion in children with pycnodysostosis and improved linear growth after growth hormone treatment. Archives of Disease in Childhood 75(3): 242-244
Honkanen, A.; Ovaska, T.; Korpi, E.R. 1995: Defective habituation to nociceptive stimulation in alcohol-avoiding ANA rats. Psychopharmacology 120(1): 21-27
Mayatepek, E.; Lehmann, W.D. 1996: Defective hepatobiliary leukotriene elimination in patients with the Dubin-Johnson syndrome. Clinica Chimica Acta; International Journal of Clinical Chemistry 249(1-2): 37-46
Ho, D.Y.; Saydam, T.C.; Fink, S.L.; Lawrence, M.S.; Sapolsky, R.M. 1995: Defective herpes simplex virus vectors expressing the rat brain glucose transporter protect cultured neurons from necrotic insults. Journal of Neurochemistry 65(2): 842-850
Fink, S.L.; Chang, L.K.; Ho, D.Y.; Sapolsky, R.M. 1997: Defective herpes simplex virus vectors expressing the rat brain stress-inducible heat shock protein 72 protect cultured neurons from severe heat shock. Journal of Neurochemistry 68(3): 961-969
Miyatake, S.; Martuza, R.L.; Rabkin, S.D. 1997: Defective herpes simplex virus vectors expressing thymidine kinase for the treatment of malignant glioma. Cancer Gene Therapy 4(4): 222-228
DiSanto, J.P.; Rieux-Laucat, F.; Dautry-Varsat, A.; Fischer, A.; de Saint Basile, G. 1994: Defective human interleukin 2 receptor gamma chain in an atypical X chromosome-linked severe combined immunodeficiency with peripheral T cells. Proceedings of the National Academy of Sciences of the United States of America 91(20): 9466-9470
Paggi, M.G.; Martelli, F.; Fanciulli, M.; Felsani, A.; Sciacchitano, S.; Varmi, M.; Bruno, T.; Carapella, C.M.; Floridi, A. 1994: Defective human retinoblastoma protein identified by lack of interaction with the E1A oncoprotein. Cancer Research 54(4): 1098-1104
degli Uberti, E.C.; Ambrosio, M.R.; Cella, S.G.; Margutti, A.R.; Trasforini, G.; Rigamonti, A.E.; Petrone, E.; Müller, E.E. 1997: Defective hypothalamic growth hormone (GH)-releasing hormone activity may contribute to declining GH secretion with age in man. Journal of Clinical Endocrinology and Metabolism 82(9): 2885-2888
Chikanza, I.C.; Petrou, P.; Kingsley, G.; Chrousos, G.; Panayi, G.S. 1992: Defective hypothalamic response to immune and inflammatory stimuli in patients with rheumatoid arthritis. Arthritis and Rheumatism 35(11): 1281-1288
Goldenberg, G. 1996: Defective imitation of gestures in patients with damage in the left or right hemispheres. Journal of Neurology Neurosurgery and Psychiatry 61(2): 176-180
Morra, L.; Moccia, F.; Mazzarello, G.P.; Bessone, G.; Mela, G.S.; Ponassi, G.A. 1993: Defective in vitro growth of BFU-E of elderly subjects revealed by hydrocortisone. Biomedicine and Pharmacotherapy 47(4): 167-171
Chan, L.S.; Fine, J.D.; Hammerberg, C.; Bauer, E.A.; Cooper, K.D. 1995: Defective in vivo expression and apparently normal in vitro expression of a newly identified 105-kDa lower lamina lucida protein in dystrophic epidermolysis bullosa. British Journal of Dermatology 132(5): 725-729
Juvonen, E.; Mäkitie, O.; Mäkipernaa, A.; Ruutu, T.; Kaitila, I.; Rajantie, J. 1995: Defective in-vitro colony formation of haematopoietic progenitors in patients with cartilage-hair hypoplasia and history of anaemia. European Journal of Pediatrics 154(1): 30-34
Rolfe, B.G.; Carlson, R.W.; Ridge, R.W.; Dazzo, F.B.; Mateos, P.F.; Pankhurst, C.E. 1996: Defective infection and nodulation of covers by exopolysaccharide mutants of Rhizobium leguminosarum bv. trifolii. Australian Journal of Plant Physiology 23(3): 285-303
Shimizu, T.; Hansson, G.C.; Strandvik, B. 1994: Defective inhibition by dexamethasone of leukotriene B4 and C4 production by leukocytes in patients with cystic fibrosis. Prostaglandins Leukotrienes and Essential Fatty Acids 51(6): 407-410
Kelly, P.H. 1998: Defective inhibition of dream event memory formation: a hypothesized mechanism in the onset and progression of symptoms of schizophrenia. Brain Research Bulletin 46(3): 189-197
Tedeschi, A.; Cottini, M.; Salmaso, C.; Milazzo, N.; Miadonna, A. 1996: Defective inhibition of sodium on basophil histamine release in patients with allergic rhinitis and bronchial asthma. European Respiratory Journal 9(10): 2070-2076
Petruzziello, A.; Formisano, P.; Miele, C.; Di Finizio, B.; Riccardi, G.; Ferrara, A.; Beguinot, L.; Beguinot, F. 1993: Defective insulin action in fibroblasts from noninsulin-dependent diabetes mellitus patients with Gln1152 insulin receptor mutation. Journal of Clinical Endocrinology and Metabolism 77(2): 409-412
Hirose, H.; Maruyama, H.; Kido, K.; Ito, K.; Koyama, K.; Tashiro, Y.; Saruta, T. 1995: Defective insulin and glucagon secretion in isolated perfused pancreata of diabetic WBN/Kob rats. Pancreas 10(1): 71-77
Marita, R.A.; Sawant, N.; Sawant, N.N.; Desai, A.P.; Dalal, K.P. 1997: Defective insulin binding in non-insulin dependent diabetes mellitus and obesity is associated with decreased insulin stimulation of glucose metabolism in human mononuclear cells. Medical Science Research 25(2): 123-126
Miki, T.; Nagashima, K.; Tashiro, F.; Kotake, K.; Yoshitomi, H.; Tamamoto, A.; Gonoi, T.; Iwanaga, T.; Miyazaki, J.; Seino, S. 1998: Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice. Proceedings of the National Academy of Sciences of the United States of America 95(18): 10402-10406
Pontoglio, M.; Sreenan, S.; Roe, M.; Pugh, W.; Ostrega, D.; Doyen, A.; Pick, A.J.; Baldwin, A.; Velho, G.; Froguel, P.; Levisetti, M.; Bonner-Weir, S.; Bell, G.I.; Yaniv, M.; Polonsky, K.S. 1998: Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice. Journal of Clinical Investigation 101(10): 2215-2222
Thon, V.; Wolf, H.M.; Sasgary, M.; Litzman, J.; Samstag, A.; Hauber, I.; Lokaj, J.; Eibl, M.M. 1997: Defective integration of activating signals derived from the T cell receptor (TCR) and costimulatory molecules in both CD4+ and CD8+ T lymphocytes of common variable immunodeficiency (CVID) patients. Clinical and Experimental Immunology 110(2): 174-181
Brown, T.A.; Gil, S.G.; Sybert, V.P.; Lestringant, G.G.; Tadini, G.; Caputo, R.; Carter, W.G. 1996: Defective integrin alpha 6 beta 4 expression in the skin of patients with junctional epidermolysis bullosa and pyloric atresia. Journal of Investigative Dermatology 107(3): 384-391
Arnaud, J.; Chenu, C.; Huchenq, A.; Gouaillard, C.; Kuhlmann, J.; Rubin, B. 1996: Defective interactions between TCR chains and CD3 heterodimers prevent membrane expression of TCR-alpha beta in human T cells. Journal of Immunology 156(6): 2155-2162
Noble, S.; Dimmock, N.J. 1994: Defective interfering type A equine influenza virus (H3N8) protects mice from morbidity and mortality caused by homologous and heterologous subtypes of influenza A virus. Journal of General Virology 75: 3485-3491
Rodriguez-Zapata, M.; Salmeron, I.; Manzano, L.; Salmeron, O.J.; Prieto, A.; Alvarez-Mon, M. 1996: Defective interferon-gamma production by T-lymphocytes from patients with acute brucellosis. European Journal of Clinical Investigation 26(2): 136-140
Swain, M.G.; Maric, M.; Carter, L. 1995: Defective interleukin-1-induced ACTH release in cholestatic rats: impaired hypothalamic PGE2 release. American Journal of Physiology 268(3 Pt 1): G404-G409
Suresh, K.; Jayavardhanan, K.K.; Vasudevan, D.M. 1995: Defective interleukin-2 R gene expression in gastric carcinoma patients. Immunological Investigations 24(4): 565-571
Fischer, M.B.; Hauber, I.; Vogel, E.; Wolf, H.M.; Mannhalter, J.W.; Eibl, M.M. 1993: Defective interleukin-2 and interferon-gamma gene expression in response to antigen in a subgroup of patients with common variable immunodeficiency. Journal of Allergy and Clinical Immunology 92(2): 340-352
Guida, S.; Fiore, M.; Scotese, I.; Iorio, R.; Gaetaniello, L.; Vegnente, A.; Pignata, C. 1997: Defective interleukin-2 production in children with chronic hepatitis B: role of adherent cells. Journal of Pediatric Gastroenterology and Nutrition 24(3): 312-316
Sturla, L.; Etzioni, A.; Bisso, A.; Zanardi, D.; De Flora, G.; Silengo, L.; De Flora, A.; Tonetti, M. 1998: Defective intracellular activity of GDP-D-mannose-4,6-dehydratase in leukocyte adhesion deficiency type II syndrome. Febs Letters 429(3): 274-278
Estrada, G.; Krasinski, S.D.; Grand, R.J.; López-Tejero, M.D. 1998: Defective intracellular processing of lactase-phlorizin hydrolase protein in rats prenatally exposed to ethanol. Alcoholism Clinical and Experimental Research 22(5): 1177-1183
Colley, N.J.; Cassill, J.A.; Baker, E.K.; Zuker, C.S. 1995: Defective intracellular transport is the molecular basis of rhodopsin-dependent dominant retinal degeneration. Proceedings of the National Academy of Sciences of the United States of America 92(7): 3070-3074
Shibata, H.; Fukushi, M.; Igarashi, A.; Misumi, Y.; Ikehara, Y.; Ohashi, Y.; Oda, K. 1998: Defective intracellular transport of tissue-nonspecific alkaline phosphatase with an Ala162fwdarwThr mutation associated with lethal hypophosphatasia. Journal of Biochemistry (Tokyo) 123(5): 968-977
Cazzola, M.; Ponchio, L.; de Benedetti, F.; Ravelli, A.; Rosti, V.; Beguin, Y.; Invernizzi, R.; Barosi, G.; Martini, A. 1996: Defective iron supply for erythropoiesis and adequate endogenous erythropoietin production in the anemia associated with systemic-onset juvenile chronic arthritis. Blood 87(11): 4824-4830
Goodwin, S.F.; Del Vecchio, M.; Velinzon, K.; Hogel, C.; Russell, S.R.; Tully, T.; Kaiser, K. 1997: Defective learning in mutants of the Drosophila gene for a regulatory subunit of cAMP-dependent protein kinase. Journal of Neuroscience: the Official Journal of the Society for Neuroscience 17(22): 8817-8827
Perez-Castro, A.V.; Tran, V.T.; Nguyen-Huu, M.C. 1993: Defective lens fiber differentiation and pancreatic tumorigenesis caused by ectopic expression of the cellular retinoic acid-binding protein I. Development 119(2): 363-375
Yamamoto, N.; Naraparaju, V.R.; Orchard, P.J. 1996: Defective lymphocyte glycosidases in the macrophage activation cascade of juvenile osteopetrosis. Blood 88(4): 1473-1478
Nosaka, T.; van Deursen, J.M.; Tripp, R.A.; Thierfelder, W.E.; Witthuhn, B.A.; McMickle, A.P.; Doherty, P.C.; Grosveld, G.C.; Ihle, J.N. 1995: Defective lymphoid development in mice lacking Jak3. Science 270(5237): 800-802
Guilloux, Y.; Viret, C.; Gervois, N.; Le Dréan, E.; Pandolfino, M.C.; Diez, E.; Jotereau, F. 1994: Defective lymphokine production by most CD8+ and CD4+ tumor-specific T cell clones derived from human melanoma-infiltrating lymphocytes in response to autologous tumor cells in vitro. European Journal of Immunology 24(9): 1966-1973
Krishnamurthy, G.; Kher, V.; Naik, S. 1995: Defective lymphoproliferative responses & interleukin-2 production in chronic renal failure patients. Indian Journal of Medical Research 102: 281-286
Jakobsen, M.K.; Restifo, N.P.; Cohen, P.A.; Marincola, F.M.; Cheshire, L.B.; Linehan, W.M.; Rosenberg, S.A.; Alexander, R.B. 1995: Defective major histocompatibility complex class I expression in a sarcomatoid renal cell carcinoma cell line. Journal of ImmunoTherapy with Emphasis on Tumor Immunology: Official Journal of the Society for Biological Therapy 17(4): 222-228
Camp, L.A.; Chauhan, P.; Farrar, J.D.; Lehrman, M.A. 1993: Defective mannosylation of glycosylphosphatidylinositol in Lec35 Chinese hamster ovary cells. Journal of Biological Chemistry 268(9): 6721-6728
Jansen, A.; Van Hagen, M.; Drexhage, H.A. 1995: Defective maturation and function of antigen-presenting cells in type 1 diabetes. Lancet 345(8948): 491-492
Kellokumpu, S.; Sormunen, R.; Väänänen, H.K.; Metsikkö, K. 1995: Defective maturation of a viral glycoprotein and partial loss of the Golgi stack structure during in vitro myogenesis. Experimental Cell Research 220(1): 101-111
Sidhu, M.S.; Crowley, J.; Lowenthal, A.; Karcher, D.; Menonna, J.; Cook, S.; Udem, S.; Dowling, P. 1994: Defective measles virus in human subacute sclerosing panencephalitis brain. Virology 202(2): 631-641
Kiley, S.C.; Parker, P.J. 1997: Defective microtubule reorganization in phorbol ester-resistant U937 variants: reconstitution of the normal cell phenotype with nocodazole treatment. Cell Growth and Differentiation: the Molecular Biology Journal of the American Association for Cancer Research 8(2): 231-242
Umar, A.; Boyer, J.C.; Thomas, D.C.; Nguyen, D.C.; Risinger, J.I.; Boyd, J.; Ionov, Y.; Perucho, M.; Kunkel, T.A. 1994: Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability. Journal of Biological Chemistry 269(20): 14367-14370
Jackson, E.K.; Herzer, W.A. 1994: Defective modulation of angiotensin II-induced renal vasoconstriction in hypertensive rats. Hypertension 23(3): 329-336
Goldhill, J.M.; Burakoff, R.; Donovan, V.; Rose, K.; Percy, W.H. 1993: Defective modulation of colonic secretomotor neurons in a rabbit model of colitis. American Journal of Physiology 264(4 Pt 1): G671-G677
Mize, C.; Johnson, J.L.; Rajagopalan, K.V. 1995: Defective molybdopterin biosynthesis: clinical heterogeneity associated with molybdenum cofactor deficiency. Journal of Inherited Metabolic Disease 18(3): 283-290
Frucht, D.M.; Holland, S.M. 1996: Defective monocyte costimulation for IFN-gamma production in familial disseminated Mycobacterium avium complex infection: abnormal IL-12 regulation. Journal of Immunology 157(1): 411-416
Vázquez-Doval, J.; Sánchez-Ibarrola, A. 1993: Defective mononuclear phagocyte function in systemic lupus erythematosus: relationship of FcRII (CD32) with intermediate cytoskeletal filaments. Journal of Investigational Allergology and Clinical Immunology 3(2): 86-91
Brandon, E.P.; Logue, S.F.; Adams, M.R.; Qi, M.; Sullivan, S.P.; Matsumoto, A.M.; Dorsa, D.M.; Wehner, J.M.; McKnight, G.S.; Idzerda, R.L. 1998: Defective motor behavior and neural gene expression in RIIbeta-protein kinase A mutant mice. Journal of Neuroscience: the Official Journal of the Society for Neuroscience 18(10): 3639-3649
Fontana, G.A.; Pantaleo, T.; Lavorini, F.; Benvenuti, F.; Gangemi, S. 1998: Defective motor control of coughing in Parkinson's disease. American Journal of Respiratory and Critical Care Medicine 158(2): 458-464
Rohrer, D.K.; Blau, H.M. 1996: Defective myogenesis in NFB-s mutant associated with a saturable suppression of MYF5 activity. Somatic Cell and Molecular Genetics 22(5): 349-361
Ullum, H.; Gøtzsche, P.C.; Victor, J.; Dickmeiss, E.; Skinhøj, P.; Pedersen, B.K. 1995: Defective natural immunity: an early manifestation of human immunodeficiency virus infection. Journal of Experimental Medicine 182(3): 789-799
Ogata, K.; Fujii, H.; Yokose, N.; An, E.; Tamura, H.; Kamikubo, K.; Dan, K.; Hamaguchi, H.; Sakamaki, H.; Onozawa, Y. 1994: Defective natural killer (NK) cell-mediated cytotoxicity does not imply clonal involvement of NK cells in myelodysplastic syndromes. British Journal of Haematology 87(2): 396-398
Yamaguchi, Y.; Takashima, I.; Funakoshi, M.; Kawami, H.; Toge, T. 1994: Defective natural killer activity in gastric cancer patients: possible involvement of suppressor factor receptor. In Vivo 8(3): 279-283
Papadaki, H.A.; Coulocheri, S.; Xylouri, I.; Chatzivassili, A.; Konsolas, J.; Katrinakis, G.; Karkavitsas, N.; Eliopoulos, G.D. 1998: Defective natural killer cell activity of peripheral blood lymphocytes correlates with the degree of neutropenia in patients with chronic idiopathic neutropenia of adults. Annals of Hematology 76(3-4): 127-134
Sullivan, K.E.; Delaat, C.A.; Douglas, S.D.; Filipovich, A.H. 1998: Defective natural killer cell function in patients with hemophagocytic lymphohistiocytosis and in first degree relatives. Pediatric Research 44(4): 465-468
Chan, V.W.; Lowell, C.A.; DeFranco, A.L. 1998: Defective negative regulation of antigen receptor signaling in Lyn-deficient B lymphocytes. Current Biology: Cb 8(10): 545-553
Gautam, M.; Noakes, P.G.; Moscoso, L.; Rupp, F.; Scheller, R.H.; Merlie, J.P.; Sanes, J.R. 1996: Defective neuromuscular synaptogenesis in agrin-deficient mutant mice. Cell 85(4): 525-535
Ghate, H.V.; Padhye, A.D.; Ghaskadbi, S. 1996: Defective neurulation in frog embryos exposed to dilute sea water. Current Science 71(4): 320-326
Biasucci, G.; Gigliotti, M.; Luotti, D.; Bertagnolio, B.; Riva, E. 1995: Defective neutrophil activity in fructose-1,6-diphosphatase deficiency. Journal of Inherited Metabolic Disease 18(2): 162-164
Queiroz, M.L.; Bincoletto, C.; Perlingeiro, R.C.; Souza, C.A.; Toledo, H. 1997: Defective neutrophil function in workers occupationally exposed to hexachlorobenzene. Human and Experimental Toxicology 16(6): 322-326
Queiroz, M.L.; Almeida, M.; Gallão, M.I.; Höehr, N.F. 1993: Defective neutrophil function in workers occupationally exposed to lead. Pharmacology and Toxicology 72(2): 73-77
Eigenthaler, M.; Ullrich, H.; Geiger, J.; Horstrup, K.; Hönig-Liedl, P.; Wiebecke, D.; Walter, U. 1993: Defective nitrovasodilator-stimulated protein phosphorylation and calcium regulation in cGMP-dependent protein kinase-deficient human platelets of chronic myelocytic leukemia. Journal of Biological Chemistry 268(18): 13526-13531
Reubinoff, B.E.; Simon, A.; Friedler, S.; Schenker, J.G.; Lewin, A. 1994: Defective oocytes as a possible cause of infertility in a beta-thalassaemia major patient. Human Reproduction 9(6): 1143-1145
Ishikawa, N.; Eguchi, K.; Ohmori, T.; Momotani, N.; Nagayama, Y.; Hosoya, T.; Oguchi, H.; Mimura, T.; Kimura, S.; Nagataki, S.; Ito, K. 1996: Defective organification of iodide causing congenital goitrous hypothyroidism. Journal of Clinical Endocrinology and Metabolism 81(1): 376-383
Symoens, F.; Laverty, S.; Breton, L. 1993: Defective ossification of the carpal and tarsal cuboidal bones in foals. Medecin Veterinaire du Quebec 23(4): 162-168
Mayatepek, E.; Wanders, R.J. 1998: Defective oxidation of hydroxyeicosatetraenoic acids in the liver of patients with Zellweger syndrome. Journal of Inherited Metabolic Disease 21(3): 295-297
Schindler, M.; Grabski, S.; Hoff, E.; Simon, S.M. 1996: Defective pH regulation of acidic compartments in human breast cancer cells (MCF-7) is normalized in adriamycin-resistant cells (MCF-7adr). Biochemistry 35(9): 2811-2817
Dukes, I.D.; Sreenan, S.; Roe, M.W.; Levisetti, M.; Zhou, Y.P.; Ostrega, D.; Bell, G.I.; Pontoglio, M.; Yaniv, M.; Philipson, L.; Polonsky, K.S. 1998: Defective pancreatic beta-cell glycolytic signaling in hepatocyte nuclear factor-1alpha-deficient mice. Journal of Biological Chemistry 273(38): 24457-24464
Seedorf, U.; Raabe, M.; Ellinghaus, P.; Kannenberg, F.; Fobker, M.; Engel, T.; Denis, S.; Wouters, F.; Wirtz, K.W.; Wanders, R.J.; Maeda, N.; Assmann, G. 1998: Defective peroxisomal catabolism of branched fatty acyl coenzyme A in mice lacking the sterol carrier protein-2/sterol carrier protein-x gene function. Genes and Development 12(8): 1189-1201
Prozorov, A.A. 1996: Defective phages of bacilli: cell parasites or chromosomal components. Genetika 32(4): 469-481
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Puré, E.; Camp, R.L.; Peritt, D.; Panettieri, R.A.; Lazaar, A.L.; Nayak, S. 1995: Defective phosphorylation and hyaluronate binding of CD44 with point mutations in the cytoplasmic domain. Journal of Experimental Medicine 181(1): 55-62
Santini, S.A.; Marra, G.; Giardina, B.; Cotroneo, P.; Mordente, A.; Martorana, G.E.; Manto, A.; Ghirlanda, G. 1997: Defective plasma antioxidant defenses and enhanced susceptibility to lipid peroxidation in uncomplicated IDDM. Diabetes 46(11): 1853-1858
Van Der Velden, A.; Kaminski, A.; Jackson, R.J.; Belsham, G.J. 1995: Defective point mutants of the encephalomyocarditis virus internal ribosome entry site can be complemented in trans. Virology 214(1): 82-90
Lejeune, M.; Sariban, E.; Cantinieaux, B.; Ferster, A.; Devalck, C.; Fondu, P. 1996: Defective polymorphonuclear leukocyte functions in children receiving chemotherapy for cancer are partially restored by recombinant human granulocyte colony-stimulating factor in vitro. Journal of Infectious Diseases 174(4): 800-805
Frisan, T.; Zhang, Q.J.; Levitskaya, J.; Coram, M.; Kurilla, M.G.; Masucci, M.G. 1996: Defective presentation of MHC class I-restricted cytotoxic T-cell epitopes in Burkitt's lymphoma cells. International Journal of Cancer 68(2): 251-258
Ross, D.; Ziff, E. 1994: Defective processing of human adenovirus 2 late transcription unit mRNAs during abortive infections in monkey cells. Virology 202(1): 107-115
Robertson, B.J.; Moehring, J.M.; Moehring, T.J. 1993: Defective processing of the insulin receptor in an endoprotease-deficient Chinese hamster cell strain is corrected by expression of mouse furin. Journal of Biological Chemistry 268(32): 24274-24277
Mokhtarian, F.; Shi, Y.; Shirazian, D.; Morgante, L.; Miller, A.; Grob, D. 1994: Defective production of anti-inflammatory cytokine, TGF-beta by T cell lines of patients with active multiple sclerosis. Journal of Immunology 152(12): 6003-6010
Ridgway, D.; Borzy, M.S. 1992: Defective production of granulocyte-macrophage colony-stimulating factor and interleukin-1 by mononuclear cells from children treated for acute lymphoblastic leukemia. Leukemia 6(8): 809-813
Delia, S.; Mastroianni, C.M.; Lichtner, M.; Mengoni, F.; Moretti, S.; Vullo, V. 1995: Defective production of interferon-gamma and tumour necrosis factor-alpha by AIDS mononuclear cells after in vitro exposure to Rhodococcus equi. Mediators of Inflammation 4(4): 306-309
Briceño, L.; Mosca, W. 1996: Defective production of interleukin 2 in patients with Chagas' disease. Purified IL-2 augments in vitro response in patients with chagasic cardiomyopathy. Memorias do Instituto Oswaldo Cruz 91(5): 601-607
Klüter, H.; Vieregge, P.; Stolze, H.; Kirchner, H. 1995: Defective production of interleukin-2 in patients with idiopathic Parkinson's disease. Journal of the Neurological Sciences 133(1-2): 134-139
Furuta, M.; Yano, H.; Zhou, A.; Rouillé, Y.; Holst, J.J.; Carroll, R.; Ravazzola, M.; Orci, L.; Furuta, H.; Steiner, D.F. 1997: Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2. Proceedings of the National Academy of Sciences of the United States of America 94(13): 6646-6651
Moreno-Otero, R.; Murakawa, Y.; Kanof, M.E.; Civeira, M.P.; Jones, E.A.; James, S.P. 1994: Defective proliferation and regulatory function of CD4+ T cells bearing Leu-8 homing receptor in primary biliary cirrhosis. Phorbol myristate acetate enhances T-cell function. Digestive Diseases and Sciences 39(6): 1329-1336
Nelles, E.; Bützler, C.; Jung, D.; Temme, A.; Gabriel, H.D.; Dahl, U.; Traub, O.; Stümpel, F.; Jungermann, K.; Zielasek, J.; Toyka, K.V.; Dermietzel, R.; Willecke, K. 1996: Defective propagation of signals generated by sympathetic nerve stimulation in the liver of connexin32-deficient mice. Proceedings of the National Academy of Sciences of the United States of America 93(18): 9565-9570
Bingham, B.R.; Monk, P.N.; Helm, B.A. 1994: Defective protein phosphorylation and Ca2+ mobilization in a low secreting variant of the rat basophilic leukemia cell line. Journal of Biological Chemistry 269(30): 19300-19306
Cayota, A.; Vuillier, F.; Siciliano, J.; Dighiero, G. 1994: Defective protein tyrosine phosphorylation and altered levels of p59fyn and p56lck in CD4 T cells from HIV-1 infected patients. International Immunology 6(4): 611-621
Schnermann, J.; Chou, C.L.; Ma, T.; Traynor, T.; Knepper, M.A.; Verkman, A.S. 1998: Defective proximal tubular fluid reabsorption in transgenic aquaporin-1 null mice. Proceedings of the National Academy of Sciences of the United States of America 95(16): 9660-9664
Rodriguez-Zapata, M.; Reyes, E.; Sanchez, L.; Espinosa, A.; Solera, J.; Alvarez-Mon, M. 1997: Defective reactive oxygen metabolite generation by macrophages from acute brucellosis patients. Infection 25(3): 187-188
Longo, N. 1993: Defective receptors for platelet-derived growth factor AA in human fibroblasts with mutant insulin receptors. Biochemical and Biophysical Research Communications 197(2): 812-817
Nelson, D.J.; Holt, P.G. 1995: Defective regional immunity in the respiratory tract of neonates is attributable to hyporesponsiveness of local dendritic cells to activation signals. Journal of Immunology 155(7): 3517-3524
Klimiuk, P.A.; Bernacka, K.; Kuryliszyn Moskal, A. 1995: Defective regulation of apoptosis and autoimmune diseases. Reumatologia 33(1): 54-58
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Test, S.T.; Woolworth, V.S. 1994: Defective regulation of complement by the sickle erythrocyte: evidence for a defect in control of membrane attack complex formation. Blood 83(3): 842-852
Even, P.C.; Decrouy, A.; Chinet, A. 1994: Defective regulation of energy metabolism in mdx-mouse skeletal muscles. Biochemical Journal 304: 649-654
Pralong, F.P.; Pavlou, S.N.; Waldstreicher, J.; Crowley, W.F.; Boepple, P.A. 1995: Defective regulation of glycoprotein free alpha-subunit in males with isolated gonadotropin-releasing hormone deficiency--a clinical research center study. Journal of Clinical Endocrinology and Metabolism 80(12): 3682-3688
Walter, M.; Reinecke, H.; Gerdes, U.; Nofer, J.R.; Höbbel, G.; Seedorf, U.; Assmann, G. 1996: Defective regulation of phosphatidylcholine-specific phospholipases C and D in a kindred with Tangier disease. Evidence for the involvement of phosphatidylcholine breakdown in HDL-mediated cholesterol efflux mechanisms. Journal of Clinical Investigation 98(10): 2315-2323
Malmström, R.; Packard, C.J.; Caslake, M.; Bedford, D.; Stewart, P.; Yki-Järvinen, H.; Shepherd, J.; Taskinen, M.R. 1997: Defective regulation of triglyceride metabolism by insulin in the liver in NIDDM. Diabetologia 40(4): 454-462
Francis, G.A.; Knopp, R.H.; Oram, J.F. 1995: Defective removal of cellular cholesterol and phospholipids by apolipoprotein A-I in Tangier Disease. Journal of Clinical Investigation 96(1): 78-87
Badie, C.; Iliakis, G.; Foray, N.; Alsbeih, G.; Pantellias, G.E.; Okayasu, R.; Cheong, N.; Russell, N.S.; Begg, A.C.; Arlett, C.F. 1995: Defective repair of DNA double-strand breaks and chromosome damage in fibroblasts from a radiosensitive leukemia patient. Cancer Research 55(6): 1232-1234
Guo, K.; Major, G.; Foster, H.; Bassendine, M.; Collier, J.; Ross, D.; Griffiths, I. 1995: Defective repair of O6-methylguanine-DNA in primary Sjögren's syndrome patients predisposed to lymphoma. Annals of the Rheumatic Diseases 54(3): 229-232
Driggers, W.J.; Grishko, V.I.; LeDoux, S.P.; Wilson, G.L. 1996: Defective repair of oxidative damage in the mitochondrial DNA of a xeroderma pigmentosum group a cell line. Cancer Research 56(6): 1262-1266
Misra, R.R.; Vos, J.M. 1993: Defective replication of psoralen adducts detected at the gene-specific level in xeroderma pigmentosum variant cells. Molecular and Cellular Biology 13(2): 1002-1012
Mariotti, C.; Tiranti, V.; Carrara, F.; Dallapiccola, B.; DiDonato, S.; Zeviani, M. 1994: Defective respiratory capacity and mitochondrial protein synthesis in transformant cybrids harboring the tRNA(Leu(UUR)) mutation associated with maternally inherited myopathy and cardiomyopathy. Journal of Clinical Investigation 93(3): 1102-1107
Ausiello, C.M.; Sestili, P.; Locardi, C.; Logozzi, M.; Rizza, P.; Parlanti, E.; Yang, L.; Modica, A.; Modesti, A.; Musiani, P. 1994: Defective response to T cell mitogens in mice injected with human immunodeficiency virus type 1-infected U937 cells. Journal of General Virology 75: 2789-2794
Muraoka, K.; Ishii, E.; Tsuji, K.; Yamamoto, S.; Yamaguchi, H.; Hara, T.; Koga, H.; Nakahata, T.; Miyazaki, S. 1997: Defective response to thrombopoietin and impaired expression of c-mpl mRNA of bone marrow cells in congenital amegakaryocytic thrombocytopenia. British Journal of Haematology 96(2): 287-292
Bera, T.K.; Tsukamoto, T.; Panda, D.K.; Huang, T.; Guzman, R.C.; Hwang, S.I.; Nandi, S. 1998: Defective retrovirus insertion activates c-Ha-ras protooncogene in an MNU-induced rat mammary carcinoma. Biochemical and Biophysical Research Communications 248(3): 835-840
Sugiyama, K.; Sugimura, T.; Esumi, H. 1993: Defective secretion of albumin encoded by exon-skipped mRNA found in aged analbuminemic rat liver. European Journal of Cell Biology 61(2): 239-246
Chen, C.; Martin, T.M.; Stevens, S.; Rittenberg, M.B. 1994: Defective secretion of an immunoglobulin caused by mutations in the heavy chain complementarity determining region 2. Journal of Experimental Medicine 180(2): 577-586
Laffi, G.; Marra, F.; Failli, P.; Ruggiero, M.; Cecchi, E.; Carloni, V.; Giotti, A.; Gentilini, P. 1993: Defective signal transduction in platelets from cirrhotics is associated with increased cyclic nucleotides. Gastroenterology 105(1): 148-156
Fuse, I.; Mito, M.; Hattori, A.; Higuchi, W.; Shibata, A.; Ushikubi, F.; Okuma, M.; Yahata, K. 1993: Defective signal transduction induced by thromboxane A2 in a patient with a mild bleeding disorder: impaired phospholipase C activation despite normal phospholipase A2 activation. Blood 81(4): 994-1000
Mitsui, T.; Yokoyama, S.; Shimizu, Y.; Katsuura, M.; Akiba, K.; Hayasaka, K. 1997: Defective signal transduction through the thromboxane A2 receptor in a patient with a mild bleeding disorder: deficiency of the inositol 1,4,5-triphosphate formation despite normal G-protein activation. Thrombosis and Haemostasis 77(5): 991-995
Mirza, N.M.; Relias, V.; Yunis, E.J.; Pachas, W.N.; Dasgupta, J.D. 1993: Defective signal transduction via T-cell receptor-CD3 structure in T cells from rheumatoid arthritis patients. Human Immunology 36(2): 91-98
Thomas, T.J.; Gunnia, U.B.; Seibold, J.R.; Thomas, T. 1995: Defective signal-transduction pathways in T-cells from autoimmune MRL-lpr/lpr mice are associated with increased polyamine concentrations. Biochemical Journal 311: 175-182
Khanna, K.K.; Yan, J.; Watters, D.; Hobson, K.; Beamish, H.; Spring, K.; Shiloh, Y.; Gatti, R.A.; Lavin, M.F. 1997: Defective signaling through the B cell antigen receptor in Epstein-Barr virus-transformed ataxia-telangiectasia cells. Journal of Biological Chemistry 272(14): 9489-9495
Pfeifer, A.; Klatt, P.; Massberg, S.; Ny, L.; Sausbier, M.; Hirneiss, C.; Wang, G.X.; Korth, M.; Aszódi, A.; Andersson, K.E.; Krombach, F.; Mayerhofer, A.; Ruth, P.; Fässler, R.; Hofmann, F. 1998: Defective smooth muscle regulation in cGMP kinase I-deficient mice. EMBO Journal 17(11): 3045-3051
Menichini, P.; Inga, A.; Fronza, G.; Iannone, R.; Degan, P.; Campomenosi, P.; Abbondandolo, A. 1994: Defective splicing induced by 4NQO in the hamster hprt gene. Mutation Research 323(4): 159-165
Stover, M.L.; Primorac, D.; Liu, S.C.; McKinstry, M.B.; Rowe, D.W. 1993: Defective splicing of mRNA from one COL1A1 allele of type I collagen in nondeforming (type I) osteogenesis imperfecta. Journal of Clinical Investigation 92(4): 1994-2002
Hsieh, S.C.; Tsai, C.Y.; Sun, K.H.; Tsai, Y.Y.; Tsai, S.T.; Han, S.H.; Yu, H.S.; Yu, C.L. 1995: Defective spontaneous and bacterial lipopolysaccharide-stimulated production of interleukin-1 receptor antagonist by polymorphonuclear neutrophils of patients with active systemic lupus erythematosus. British Journal of Rheumatology 34(2): 107-112
Kaartinen, J.M.; Käär, M.L.; Ohisalo, J.J. 1994: Defective stimulation of adipocyte adenylate cyclase, blunted lipolysis, and obesity in pseudohypoparathyroidism 1a. Pediatric Research 35(5): 594-597
Goldhill, J.; Zhao, L.; Xu, Y.; Donovan, V.; Burakoff, R. 1993: Defective stimulation of cyclic AMP by prostaglandin E2 in colonic epithelial cells in colitis. European Journal of Pharmacology 238(2-3): 387-390
Brenner, R.E.; Riemenschneider, B.; Blum, W.; Mörike, M.; Teller, W.M.; Pirsig, W.; Heinze, E. 1992: Defective stimulation of proliferation and collagen biosynthesis of human bone cells by serum from diabetic patients. Acta Endocrinologica 127(6): 509-514
Goldberg, A.F.; Molday, R.S. 1996: Defective subunit assembly underlies a digenic form of retinitis pigmentosa linked to mutations in peripherin/rds and rom-1. Proceedings of the National Academy of Sciences of the United States of America 93(24): 13726-13730
Anderson, K.A.; Ribar, T.J.; Illario, M.; Means, A.R. 1997: Defective survival and activation of thymocytes in transgenic mice expressing a catalytically inactive form of Ca2+/calmodulin-dependent protein kinase IV. Molecular Endocrinology 11(6): 725-737
Finck, M.; Bergmann, N.; Jansson, B.; Ernst, J.F. 1996: Defective threonine-linked glycosylation of human insulin-like growth factor in mutants of the yeast Saccharomyces cerevisiae. Glycobiology 6(3): 313-320
McNicol, A.; Sutherland, M.; Zou, R.; Drouin, J. 1996: Defective thrombin-induced calcium changes and aggregation of Bernard-Soulier platelets are not associated with deficient moderate-affinity receptors. Arteriosclerosis Thrombosis and Vascular Biology 16(5): 628-632
Demeure, M.J.; Doffek, K.M.; Wilson, S.D. 1997: Defective thyrotropin receptor G-protein cyclic adenosine monophosphate signaling mechanism in the FTC human follicular thyroid cancer cell line. Surgery (st Louis). 122(6): 1195-1202,.
van der Horst, G.T.; van Steeg, H.; Berg, R.J.; van Gool, A.J.; de Wit, J.; Weeda, G.; Morreau, H.; Beems, R.B.; van Kreijl, C.F.; de Gruijl, F.R.; Bootsma, D.; Hoeijmakers, J.H. 1997: Defective transcription-coupled repair in Cockayne syndrome B mice is associated with skin cancer predisposition. Cell 89(3): 425-435
Cooper, P.K.; Nouspikel, T.; Clarkson, S.G.; Leadon, S.A. 1997: Defective transcription-coupled repair of oxidative base damage in Cockayne Syndrome patients from XP group G. Science 275(5302): 990-993
Jiang, Y.; Triezenberg, S.J.; Gralla, J.D. 1994: Defective transcriptional activation by diverse VP16 mutants associated with a common inability to form open promoter complexes. Journal of Biological Chemistry 269(8): 5505-5508
Morgan, C.J.; Merrill, F.L.; Trewyn, R.W. 1996: Defective transfer RNA-queuine modification in C3H10T1/2 murine fibroblasts transfected with oncogenic ras. Cancer Research 56(3): 594-598
Fuchs, P.; Agostini, H.; Minton, K.W. 1994: Defective transformation of chromosomal markers in DNA polymerase I mutants of the radioresistant bacterium Deinococcus radiodurans. Mutation Research 309(2): 175-184
Marchant, A.; Gueydan, C.; Houzet, L.; Amraoui, Z.; Sels, A.; Huez, G.; Goldman, M.; Kruys, V. 1996: Defective translation of tumor necrosis factor mRNA in lipopolysaccharide-tolerant macrophages. Journal of Inflammation 46(2): 114-123
Slapak, C.A.; Kharbanda, S.; Saleem, A.; Kufe, D.W. 1993: Defective translocation of protein kinase C in multidrug-resistant HL-60 cells confers a reversible loss of phorbol ester-induced monocytic differentiation. Journal of Biological Chemistry 268(17): 12267-12273
Partiseti, M.; Le Deist, F.; Hivroz, C.; Fischer, A.; Korn, H.; Choquet, D. 1994: Defective transmembrane calcium influx demonstrated in a primary immunodeficiency by video-imaging. Comptes Rendus de l'Academie des Sciences. Serie Iii Sciences de la Vie 317(2): 167-173
Gorlick, R.; Goker, E.; Trippett, T.; Steinherz, P.; Elisseyeff, Y.; Mazumdar, M.; Flintoff, W.F.; Bertino, J.R. 1997: Defective transport is a common mechanism of acquired methotrexate resistance in acute lymphocytic leukemia and is associated with decreased reduced folate carrier expression. Blood 89(3): 1013-1018
Maheshwari, R.K.; Sidhu, G.S.; Singh, A.K.; Sivaram, S.S.; Kinchington, P.R.; Hay, J.; Friedman, R.M. 1994: Defective transport of herpes simplex virus glycoprotein in interferon-treated cells: role of intracellular pH. Journal of Interferon Research 14(6): 319-324
Kaplitt, M.G.; Makimura, H. 1997: Defective viral vectors as agents for gene transfer in the nervous system. Journal of Neuroscience Methods 71(1): 125-132
Norén, K.; Hansen, G.H.; Clausen, H.; Norén, O.; Sjöström, H.; Vogel, L.K. 1997: Defectively N-glycosylated and non-O-glycosylated aminopeptidase N (CD13) is normally expressed at the cell surface and has full enzymatic activity. Experimental Cell Research 231(1): 112-118
Kristal, B.S.; Jackson, C.T.; Chung, H.Y.; Matsuda, M.; Nguyen, H.D.; Yu, B.P. 1997: Defects at center P underlie diabetes-associated mitochondrial dysfunction. Free Radical Biology and Medicine 22(5): 823-833
Wu, J.; Chappelow, J.; Yang, J.; Weimann, L. 1998: Defects generated in human stratum corneum specimens by ultrasound. Ultrasound in Medicine and Biology 24(5): 705-710
Thomis, D.C.; Gurniak, C.B.; Tivol, E.; Sharpe, A.H.; Berg, L.J. 1995: Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3. Science 270(5237): 794-797
Remold-O'Donnell, E.; Rosen, F.S.; Kenney, D.M. 1996: Defects in Wiskott-Aldrich syndrome blood cells. Blood 87(7): 2621-2631
Holsinger, L.J.; Graef, I.A.; Swat, W.; Chi, T.; Bautista, D.M.; Davidson, L.; Lewis, R.S.; Alt, F.W.; Crabtree, G.R. 1998: Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction. Current Biology: Cb 8(10): 563-572
Funauchi, M.; Farrant, J.; Moreno, C.; Webster, A.D. 1995: Defects in antigen-driven lymphocyte responses in common variable immunodeficiency (CVID) are due to a reduction in the number of antigen-specific CD4+ T cells. Clinical and Experimental Immunology 101(1): 82-88
Popolo, L.; Vai, M. 1998: Defects in assembly of the extracellular matrix are responsible for altered morphogenesis of a Candida albicans phr1 mutant. Journal of Bacteriology 180(1): 163-166
Gulati, S.; Chen, Z.; Brody, L.C.; Rosenblatt, D.S.; Banerjee, R. 1997: Defects in auxiliary redox proteins lead to functional methionine synthase deficiency. Journal of Biological Chemistry 272(31): 19171-19175
Kunz, B.A.; Henson, E.S.; Karthikeyan, R.; Kuschak, T.; McQueen, S.A.; Scott, C.A.; Xiao, W. 1998: Defects in base excision repair combined with elevated intracellular dCTP levels dramatically reduce mutation induction in yeast by ethyl methanesulfonate and N-methyl-N'-nitro-N-nitrosoguanidine. Environmental and Molecular Mutagenesis 32(2): 173-178
O'Meara, N.M.; Blackman, J.D.; Ehrmann, D.A.; Barnes, R.B.; Jaspan, J.B.; Rosenfield, R.L.; Polonsky, K.S. 1993: Defects in beta-cell function in functional ovarian hyperandrogenism. Journal of Clinical Endocrinology and Metabolism 76(5): 1241-1247
Scheeren, R.A.; Keehnen, R.M.; Meijer, C.J.; van der Baan, S. 1993: Defects in cellular immunity in chronic upper airway infections are associated with immunosuppressive retroviral p15E-like proteins. Archives of Otolaryngology--Head and Neck Surgery 119(4): 439-443
Kim, J.S.; Kim, S.H.; Chung, Y.B. 1997: Defects in concatemer processing of bacteriophage T7 DNA deleted in the M-hairpin region. Virology 236(1): 37-46
Rendahl, K.G.; Gaukhshteyn, N.; Wheeler, D.A.; Fry, T.A.; Hall, J.C. 1996: Defects in courtship and vision caused by amino acid substitutions in a putative RNA-binding protein encoded by the no-on-transient A (nonA) gene of Drosophila. Journal of Neuroscience: the Official Journal of the Society for Neuroscience 16(4): 1511-1522
Zakopailo, G.G.; Gorbatyuk, I.N.; Sheremet, Z.A.; Regan, S.N. 1993: Defects in early detection of pulmonary tuberculosis and the approaches to their correction. Problemy Tuberkuleza 1993(6): 9-11
Haerry, T.E.; Heslip, T.R.; Marsh, J.L.; O'Connor, M.B. 1997: Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila. Development 124(16): 3055-3064
Subramaniam, M.; Frenette, P.S.; Saffaripour, S.; Johnson, R.C.; Hynes, R.O.; Wagner, D.D. 1996: Defects in hemostasis in P-selectin-deficient mice. Blood 87(4): 1238-1242
Gulati, S.; Baker, P.; Li, Y.N.; Fowler, B.; Kruger, W.; Brody, L.C.; Banerjee, R. 1996: Defects in human methionine synthase in cblG patients. Human Molecular Genetics 5(12): 1859-1865
Ryan, E.A.; Imes, S.; Liu, D.; McManus, R.; Finegood, D.T.; Polonsky, K.S.; Sturis, J. 1995: Defects in insulin secretion and action in women with a history of gestational diabetes. Diabetes 44(5): 506-512
Vauhkonen, I.; Niskanen, L.; Vanninen, E.; Kainulainen, S.; Uusitupa, M.; Laakso, M. 1998: Defects in insulin secretion and insulin action in non-insulin-dependent diabetes mellitus are inherited. Metabolic studies on offspring of diabetic probands. Journal of Clinical Investigation 101(1): 86-96
Saad, M.J.; Maeda, L.; Brenelli, S.L.; Carvalho, C.R.; Paiva, R.S.; Velloso, L.A. 1997: Defects in insulin signal transduction in liver and muscle of pregnant rats. Diabetologia 40(2): 179-186
Narayanan, P.K.; Ragheb, K.; Lawler, G.; Robinson, J.P. 1997: Defects in intracellular oxidative metabolism of neutrophils undergoing apoptosis. Journal of Leukocyte Biology 61(4): 481-488
Peters, K.M.; Klosterhalfen, B.; Zwadlo-Klarwasser, G.; Koberg, K.; Rosendahl, R.; Zilkens, K.W. 1993: Defects in lymphocyte subsets in chronic osteomyelitis: A prospective trial. Unfallchirurg 96(1): 29-33
Forrester, W.; Stutz, F.; Rosbash, M.; Wickens, M. 1992: Defects in mRNA 3'-end formation, transcription initiation, and mRNA transport associated with the yeast mutation prp20: possible coupling of mRNA processing and chromatin structure. Genes and Development 6(10): 1914-1926
George, E.L.; Georges-Labouesse, E.N.; Patel-King, R.S.; Rayburn, H.; Hynes, R.O. 1993: Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin. Development 119(4): 1079-1091
Homfray, T.F.; Cottrell, S.E.; Ilyas, M.; Rowan, A.; Talbot, I.C.; Bodmer, W.F.; Tomlinson, I.P. 1998: Defects in mismatch repair occur after APC mutations in the pathogenesis of sporadic colorectal tumours. Human Mutation 11(2): 114-120
Gutmann, D.H.; Geist, R.T.; Xu, H.m.; Kim, J.S.; Saporito-Irwin, S. 1998: Defects in neurofibromatosis 2 protein function can arise at multiple levels. Human Molecular Genetics 7(3): 335-345
Blagosklonny, M.V.; Prabhu, N.S.; El-Deiry, W.S. 1997: Defects in p21WAF1/CIP1, Rb, and c-myc signaling in phorbol ester-resistant cancer cells. Cancer Research 57(2): 320-325
Guo, J.; Wu, W.; Yuan, Z.Y.; Post, K.; Crouch, R.J.; Levin, J.G. 1995: Defects in primer-template binding, processive DNA synthesis, and RNase H activity associated with chimeric reverse transcriptases having the murine leukemia virus polymerase domain joined to Escherichia coli RNase H. Biochemistry 34(15): 5018-5029
Bergeron, L.; Perez, G.I.; Macdonald, G.; Shi, L.; Sun, Y.; Jurisicova, A.; Varmuza, S.; Latham, K.E.; Flaws, J.A.; Salter, J.C.; Hara, H.; Moskowitz, M.A.; Li, E.; Greenberg, A.; Tilly, J.L.; Yuan, J. 1998: Defects in regulation of apoptosis in caspase-2-deficient mice. Genes and Development 12(9): 1304-1314
Morin, X.; Cremer, H.; Hirsch, M.R.; Kapur, R.P.; Goridis, C.; Brunet, J.F. 1997: Defects in sensory and autonomic ganglia and absence of locus coeruleus in mice deficient for the homeobox gene Phox2a. Neuron 18(3): 411-423
Zachmann, M. 1995: Defects in steroidogenic enzymes. Discrepancies between clinical steroid research and molecular biology results. Journal of Steroid Biochemistry and Molecular Biology 53(1-6): 159-164
Takayama, K.; Salazar, E.P.; Lehmann, A.; Stefanini, M.; Thompson, L.H.; Weber, C.A. 1995: Defects in the DNA repair and transcription gene ERCC2 in the cancer-prone disorder xeroderma pigmentosum group D. Cancer Research 55(23): 5656-5663
Takayama, K.; Salazar, E.P.; Broughton, B.C.; Lehmann, A.R.; Sarasin, A.; Thompson, L.H.; Weber, C.A. 1996: Defects in the DNA repair and transcription gene ERCC2(XPD) in trichothiodystrophy. American Journal of Human Genetics 58(2): 263-270
van Maele-Fabry, G.; Gofflot, F.; Picard, J.J. 1996: Defects in the development of branchial nerves and ganglia induced by in vitro exposure of mouse embryos to mercuric chloride. Teratology 53(1): 10-20
Serreze, D.V.; Gaskins, H.R.; Leiter, E.H. 1993: Defects in the differentiation and function of antigen presenting cells in NOD/Lt mice. Journal of Immunology 150(6): 2534-2543
Cheknev, S.B. 1993: Defects in the interferon system as a mechanism underlying development of natural killer cell immunodeficiency. Immunologiya 1993(6): 8-12
Kysela, B.P.; Lohrer, H.; Arrand, J.E. 1995: Defects in the kinetics of the repair of DNA double-strand breaks and inhibition of DNA synthesis in the ataxia telangiectasia AT5BI-VA cell line: Comparison to a corrected hybrid, atxbc. Radiation Research 144(3): 276-281
Trijbels, F.J.; Ruitenbeek, W.; Huizing, M.; Wendel, U.; Smeitink, J.A.; Sengers, R.C. 1997: Defects in the mitochondrial energy metabolism outside the respiratory chain and the pyruvate dehydrogenase complex. Molecular and Cellular Biochemistry 174(1-2): 243-247
Koch-Nolte, F.; Klein, J.; Hollmann, C.; Kühl, M.; Haag, F.; Gaskins, H.R.; Leiter, E.; Thiele, H.G. 1995: Defects in the structure and expression of the genes for the T cell marker Rt6 in NZW and (NZB x NZW)F1 mice. International Immunology 7(5): 883-890
Holick, M.F. 1995: Defects in the synthesis and metabolism of vitamin D. Experimental and Clinical Endocrinology and Diabetes: Official Journal German Society of Endocrinology and German Diabetes Association 103(4): 219-227
Monney, L.; Otter, I.; Olivier, R.; Ozer, H.L.; Haas, A.L.; Omura, S.; Borner, C. 1998: Defects in the ubiquitin pathway induce caspase-independent apoptosis blocked by Bcl-2. Journal of Biological Chemistry 273(11): 6121-6131
Li, L.; Kaplan, J. 1998: Defects in the yeast high affinity iron transport system result in increased metal sensitivity because of the increased expression of transporters with a broad transition metal specificity. Journal of Biological Chemistry 273(35): 22181-22187
Hauser, A.R.; Fleiszig, S.; Kang, P.J.; Mostov, K.; Engel, J.N. 1998: Defects in type III secretion correlate with internalization of Pseudomonas aeruginosa by epithelial cells. Infection and Immunity 66(4): 1413-1420
Hess, J.L.; Yu, B.D.; Li, B.; Hanson, R.; Korsmeyer, S.J. 1997: Defects in yolk sac hematopoiesis in Mll-null embryos. Blood 90(5): 1799-1806
Potapenko, A.I.; Obukhova, L.K. 1992: Defects of DNA secondary structure recognized by nuclease S1. Possible role in aging of mammalian somatic cells. Izvestiya Akademii Nauk Seriya Biologicheskaya (Moscow) 1992(6): 940-943
MacLean, H.E.; Warne, G.L.; Zajac, J.D. 1995: Defects of androgen receptor function: From sex reversal to motor neurone disease. Molecular and Cellular Endocrinology 112(2): 133-141
Nakamura, H.; Kihara, Y.; Tashiro, M.; Kanagawa, K.; Shirohara, H.; Yamamoto, M.; Yoshikawa, H.; Fukumitsu, K.; Hirohata, Y.; Otsuki, M. 1998: Defects of cholecystokinin (CCK)-A receptor gene expression and CCK-A receptor-mediated biological functions in Otsuka Long-Evans Tokushima Fatty (OLETF) rats. Journal of Gastroenterology 33(5): 702-709
Sawai, S.; Shimono, A.; Wakamatsu, Y.; Palmes, C.; Hanaoka, K.; Kondoh, H. 1993: Defects of embryonic organogenesis resulting from targeted disruption of the N-myc gene in the mouse. Development 117(4): 1445-1455
Moens, C.B.; Stanton, B.R.; Parada, L.F.; Rossant, J. 1993: Defects in heart and lung development in compound heterozygotes for two different targeted mutations at the N-myc locus. Development 119(2): 485-499
Abe, Y.; Yuasa, M.; Kajiwara, Y.; Hosono, M. 1994: Defects of immune cells in the senescence-accelerated mouse: a model for learning and memory deficits in the aged. Cellular Immunology 157(1): 59-69
Artus, U.; Herbst, E.W.; Rump, J.A.; Peter, H.H. 1995: Defects of immunoglobulin-producing cells in bone marrow of patients with common variable immunodeficiency syndrome. Immunitaet und Infektion 23(2): 69-71
Christopher, M.; Hew, F.L.; Oakley, M.; Rantzau, C.; Alford, F. 1998: Defects of insulin action and skeletal muscle glucose metabolism in growth hormone-deficient adults persist after 24 months of recombinant human growth hormone therapy. Journal of Clinical Endocrinology and Metabolism 83(5): 1668-1681
Aitman, T.J.; Godsland, I.F.; Farren, B.; Crook, D.; Wong, H.J.; Scott, J. 1997: Defects of insulin action on fatty acid and carbohydrate metabolism in familial combined hyperlipidemia. Arteriosclerosis Thrombosis and Vascular Biology 17(4): 748-754
Knebel, B.; Kellner, S.; Kotzka, J.; Siemeister, G.; Dreyer, M.; Streicher, R.; Schiller, M.; Rüdiger, H.W.; Seemanova, E.; Krone, W.; Müller-Wieland, D. 1997: Defects of insulin and IGF-1 action at receptor and postreceptor level in a patient with type a syndrome of insulin resistance. Biochemical and Biophysical Research Communications 234(3): 626-630
Marth, T.; Neurath, M.; Cuccherini, B.A.; Strober, W. 1997: Defects of monocyte interleukin 12 production and humoral immunity in Whipple's disease. Gastroenterology 113(2): 442-448
Schmutz, M.; Lang, J.; Graff, S.; Brisson, A. 1994: Defects of planarity of carbon films supported on electron microscope grids revealed by reflected light microscopy. Journal of Structural Biology 112(3): 252-258
Shinkura, R.; Matsuda, F.; Sakiyama, T.; Tsubata, T.; Hiai, H.; Paumen, M.; Miyawaki, S.; Honjo, T. 1996: Defects of somatic hypermutation and class switching in alymphoplasia (aly) mutant mice. International Immunology 8(7): 1067-1075
Sapin, V.; Dollé, P.; Hindelang, C.; Kastner, P.; Chambon, P. 1997: Defects of the chorioallantoic placenta in mouse RXRalpha null fetuses. Developmental Biology 191(1): 29-41
Müller-Höcker, J.; Aust, D.; Napiwotzky, J.; Münscher, C.; Link, T.A.; Seibel, P.; Schneeweiss, S.G.; Kadenbach, B. 1996: Defects of the respiratory chain in oxyphil and chief cells of the normal parathyroid and in hyperfunction. Human Pathology 27(6): 532-541
Müller-Höcker, J.; Aust, D.; Rohrbach, H.; Napiwotzky, J.; Reith, A.; Link, T.A.; Seibel, P.; Hölzel, D.; Kadenbach, B. 1997: Defects of the respiratory chain in the normal human liver and in cirrhosis during aging. Hepatology 26(3): 709-719
Müller-Höcker, J.; Schäfer, S.; Link, T.A.; Possekel, S.; Hammer, C. 1996: Defects of the respiratory chain in various tissues of old monkeys: a cytochemical-immunocytochemical study. Mechanisms of Ageing and Development 86(3): 197-213
Aaronson, I.A.; Cakmak, M.A.; Key, L.L. 1997: Defects of the testosterone biosynthetic pathway in boys with hypospadias. Journal of Urology 157(5): 1884-1888
Miyamoto, N.; Yoshida, M.; Kuratani, S.; Matsuo, I.; Aizawa, S. 1997: Defects of urogenital development in mice lacking Emx2. Development 124(9): 1653-1664
Herno, V.; Descampiaux, B.; Kuczera, M.; Imbenotte, M.; Erb, F. 1994: Defence capacity modulation of human hepatoma cell line Hep 3B by three pesticides. Bulletin of Environmental Contamination and Toxicology 52(6): 898-904
Avellini, L.; Spaterna, A.; Reboldi, G.P.; Gaiti, A. 1993: Defence mechanisms against free radical-induced damage in sheep, cattle and dog erythrocytes. Comparative Biochemistry and Physiology. B Comparative Biochemistry 106(2): 391-394
Voegeli, R.; Meier, J.; Doppler, S. 1993: Defence strategies against reactive oxygen species: In vitro models. International Journal of Cosmetic Science 15(4): 153-161
Grant, J.W.A.; Chapman, C.A.; Richardson, K.S. 1992: Defended versus undefended home range size of carnivores, ungulates and primates. Behavioral Ecology and Sociobiology 31(3): 149-161
Moran, N.A. 1993: Defenders in the North American aphid Pemphigus obesinymphae. Insectes Sociaux 40(4): 391-402
Mori, T.; Okanoue, T.; Sawa, Y.; Hori, N.; Ohta, M.; Kagawa, K. 1993: Defenestration of the sinusoidal endothelial cell in a rat model of cirrhosis. Hepatology 17(5): 891-897
Flahaut, S.; Benachour, A.; Giard, J.C.; Boutibonnes, P.; Auffray, Y. 1996: Defense against lethal treatments and de novo protein synthesis induced by NaCl in Enterococcus faecalis ATCC 19433. Archives of Microbiology 165(5): 317-324
Regnault Roger, C.; Hamraoui, A. 1997: Defense against phytophagic insects by aromatic plants allelochemicals. Acta Botanica Gallica 144(4): 401-412
Radhamani, T.R.; Sudarshana, L.; Krishnan, R. 1995: Defense and carnivory: Dual role of bracts in Passiflora foetida. Journal of Biosciences (Bangalore) 20(5): 657-664
Azevdeo-Ramos, Claudio 1995: Defense behaviors of the neotropical treefrog Hyla geographica (Anura, Hylidae). Revista Brasileira de Biologia 55(1): 45-47
Kuz'mina, V.V. 1995: Defense function of the digestive tract of fish. Voprosy Ichtiologii 35(1): 86-93
Messiaen, J.; Van Cutsem, P. 1993: Defense gene transcription in carrot cells treatment with oligogalacturonides. Plant and Cell Physiology 34(7): 1117-1123
Albucher, R.C.; Abelson, J.L.; Nesse, R.M. 1998: Defense mechanism changes in successfully treated patients with obsessive-compulsive disorder. American Journal of Psychiatry 155(4): 558-559
Autenrieth, I.B.; Kempf, V.; Sprinz, T.; Preger, S.; Schnell, A. 1996: Defense mechanisms in Peyer's patches and mesenteric lymph nodes against Yersinia enterocolitica involve integrins and cytokines. Infection and Immunity 64(4): 1357-1368
Feldman, S.S.; Araujo, K.B.; Steiner, H. 1996: Defense mechanisms in adolescents as a function of age, sex, and mental health status. Journal of the American Academy of Child and Adolescent Psychiatry 35(10): 1344-1354
Gothelf, D.; Apter, A.; Ratzoni, G.; Orbach, I.; Weizman, R.; Tyano, S.; Pfeffer, C. 1995: Defense mechanisms in severe adolescent anorexia nervosa. Journal of the American Academy of Child and Adolescent Psychiatry 34(12): 1648-1654
Bruno, J.F.; Witman, J.D. 1996: Defense mechanisms of scleractinian cup corals against overgrowth by colonial invertebrates. Journal Of Experimental: 229-241
Weiss, B.; Ebel, R.; Elbraechter, M.; Kirchner, M.; Proksch, P. 1996: Defense metabolites from the marine sponge Verongia aerophoba. Biochemical Systematics and Ecology 24(1): 1-12
Lindquist, N.; Hay, M., E.; Fenical, W. 1992: Defense of ascidians and their conspicuous larvae: Adult vs. larval chemical defenses. Ecological Monographs 62(4): 547-568
Rendell, W.B.; Robertson, R.J. 1994: Defense of extra nest-sites by a cavity nesting bird, the tree swallow Tachycineta bicolor. Ardea 822: 273-285
Ganslosser, U.; Thermann, P. 1997: Defense of food sources influences agonistic behavior to fallow deer (Dama dama) kept in enclosures. Der Zoologische 67(4): 229-237
Greenberg, R.; Caballero, C.M.; Bichier, P. 1993: Defense of homopteran honeydew by birds in the Mexican highlands and other warm temperate forests. Oikos 68(3): 519-524
Stephenson, T.R.; Van Ballenberghe, V. 1995: Defense of one twin calf against Wolves, Canis lupus, by a female Moose, Alces alces. Canadian Field-Naturalist 109(2): 251-253
Erickson, S.; Feldman, S.S.; Steiner, H. 1997: Defense reactions and coping strategies in normal adolescents. Child Psychiatry and Human Development 28(1): 45-56
Lisachev, P.D. 1997: Defense response of foam production in snails of the genus Helix. Zhurnal Evolyutsionnoi Biokhimii i Fiziologii 33(4-5): 515-520
Tsuru, S.; Shinomiya, M.; Hata, N.; Rokutanda, M. 1992: Defense strategy against epidemic during disaster: Elimination of bacteria and viruses from drinking water using HAP filter. Journal of the National Defense Medical College 17(4): 285-286
Thienemann, M.; Shaw, R.J.; Steiner, H. 1998: Defense style and family environment. Child Psychiatry and Human Development 28(3): 189-198
Spinhoven, P.; Kooiman, C.G. 1997: Defense style in depressed and anxious psychiatric outpatients: an explorative study. Journal of Nervous and Mental Disease 185(2): 87-94
Sammallahti, P.; Aalberg, V. 1995: Defense style in personality disorders. An empirical study. Journal of Nervous and Mental Disease 183(8): 516-521
Sullivan, P.F.; Bulik, C.M.; Hall, S.; Weltzin, T.E.; Kaye, W.H. 1994: Defense style in women with eating disorders. International Journal of Eating Disorders 16(3): 251-256
Paris, J.; Zweig-Frank, H.; Bond, M.; Guzder, J. 1996: Defense styles, hostility, and psychological risk factors in male patients with personality disorders. Journal of Nervous and Mental Disease 184(3): 153-158
Blanchard, R.J.; Yudko, E.B.; Rodgers, R.J.; Blanchard, D.C. 1993: Defense system psychopharmacology: an ethological approach to the pharmacology of fear and anxiety. Behavioural Brain Research 58(1-2): 155-165
Torii, M.; Ito, H.; Suzuki, T. 1992: Defense systems for lipid peroxidation by free radicals in SHR hypertrophied myocardium. Medical Journal of Kinki University 17(4 Suppl): 39-42
Blee, K., A.; Anderson, A., J. 1996: Defense-related transcript accumulation in Phaseolus vulgaris L. colonized by the arbuscular mycorrhizal fungus Glomus intraradices Schenck and Smith. Plant Physiology (Rockville) 110(2): 675-688
Regoli, F.; Nigro, M.; Bertoli, E.; Principato, G.; Orlando, E. 1997: Defenses against oxidative stress in the Antarctic scallop Adamussium colbecki and effects of acute exposure to metals. Hydrobiologia 355: 139-144,. 3
Van Donk, Ellen 1997: Defenses in phytoplankton against grazing induced by nutrient limitation, UV-B stress and infochemicals. Aquatic Ecology 31(1): 53-58
Baird, W.F. 1996: Defensible methods of assessing fish habitat: Physical habitat assessment and modelling of the coastal areas of the lower Great Lakes Report 2370. Canadian Manuscript Report of Fisheries and Aquatic Sciences 1996(2370): I-VI, 1-39
Tal, T.; Aviram, I. 1993: Defensin interferes with the activation of neutrophil NADPH oxidase in a cell-free system. Biochemical and Biophysical Research Communications 196(2): 636-641
Higazi, A.A.; Ganz, T.; Kariko, K.; Cines, D.B. 1996: Defensin modulates tissue-type plasminogen activator and plasminogen binding to fibrin and endothelial cells. Journal of Biological Chemistry 271(30): 17650-17655
Higazi, A.A.; Lavi, E.; Bdeir, K.; Ulrich, A.M.; Jamieson, D.G.; Rader, D.J.; Usher, D.C.; Kane, W.; Ganz, T.; Cines, D.B. 1997: Defensin stimulates the binding of lipoprotein (a) to human vascular endothelial and smooth muscle cells. Blood 89(12): 4290-4298
Jones, D.E.; Bevins, C.L. 1993: Defensin-6 mRNA in human Paneth cells: implications for antimicrobial peptides in host defense of the human bowel. Febs Letters 315(2): 187-192
Martin, E.; Ganz, T.; Lehrer, R.I. 1995: Defensins and other endogenous peptide antibiotics of vertebrates. Journal of Leukocyte Biology 58(2): 128-136
Murphy, C.J.; Foster, B.A.; Mannis, M.J.; Selsted, M.E.; Reid, T.W. 1993: Defensins are mitogenic for epithelial cells and fibroblasts. Journal of Cellular Physiology 155(2): 408-413
Fujii, G.; Selsted, M.E.; Eisenberg, D. 1993: Defensins promote fusion and lysis of negatively charged membranes. Protein Science: a Publication of the Protein Society 2(8): 1301-1312
Prohászka, Z.; Német, K.; Csermely, P.; Hudecz, F.; Mezõ, G.; Füst, G. 1997: Defensins purified from human granulocytes bind C1q and activate the classical complement pathway like the transmembrane glycoprotein gp41 of HIV-1. Molecular Immunology 34(11): 809-816
Kagan, B.L.; Ganz, T.; Lehrer, R.I. 1994: Defensins: a family of antimicrobial and cytotoxic peptides. Toxicology 87(1-3): 131-149
Burger, J.; Shealer, D., A.; Gochfeld, M. 1993: Defensive aggression in terns: Discrimination and response to individual researchers. Aggressive Behavior 19(4): 303-311
Buschini, Maria Luisa, T. 1997: Defensive and intraspecific behavior of Cornitermes cumulans Kollar, 1832 (Isoptera: Termitidae) in laboratory conditions. Ciencia e Cultura (Sao Paulo). May-June; 493: 203-204
Kitaoka, A. 1994: Defensive aspects of burrowing behavior in rats (Rattus Norvegicus): a descriptive and correlational study. Behavioural Processes 31(1): 13-27
Sudakov, K.V.; Badikov, V.I. 1992: Defensive behavior in rabbits under the effects of bradykinin and cycloheximide. Fiziologicheskii Zhurnal Imeni I M Sechenova 78(9): 1-7
Zakharov, I.S. 1992: Defensive behaviour in Helix. Zhurnal Vysshei Nervnoi Deyatel'nosti Imeni I P Pavlova 42(6): 1156-1169
Wada, Y.miko; Makino, Junshiro 1993: Defensive burying in novel vs. living situations in rats. Japanese Journal of Animal Psychology 42(2): 67-76
Mashiko, K. 1998: Defensive capability of egg-guarding males of the goby, Tridentiger kuroiwae brevispinis. Ichthyological Research 45(2): 135-139
Nyklícek, I.; Vingerhoets, A.J.; Van Heck, G.L.; Van Limpt, M.C. 1998: Defensive coping in relation to casual blood pressure and self-reported daily hassles and life events. Journal of Behavioral Medicine 21(2): 145-161
Julkunen-Tiitto, Riitta 1996: Defensive efforts of Salix myrsinifolia plantlets in photomixotrophic culture conditions: The effect of sucrose, nitrogen and pH on the phytomass and secondary phenolic accumulation. Ecoscience 3(3): 297-303
Miyake, A.; Harumoto, T. 1996: Defensive function of trichocysts in Paramecium against the predatory ciliate Monodinium balbiani. European Journal of Protistology 32(1): 128-133
Høglend, P.; Perry, J.C. 1998: Defensive functioning predicts improvement in major depressive episodes. Journal of Nervous and Mental Disease 186(4): 238-243
Larson, M.R.; Langer, A.W. 1997: Defensive hostility and anger expression: Relationship to additional heart rate reactivity during active coping. Psychophysiology 34(2): 177-184
Helmers, K.F.; Krantz, D.S. 1996: Defensive hostility, gender and cardiovascular levels and responses to stress. Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine 18(4): 246-254
Prince, J.; Nolen, T.G.; Coelho, L. 1998: Defensive ink pigment processing and secretion in Aplysia californica: concentration and storage of phycoerythrobilin in the ink gland. Journal of Experimental Biology 201(Pt 10): 1595-1613
Baldwin, L.M.; Hart, L.G.; Lloyd, M.; Fordyce, M.; Rosenblatt, R.A. 1995: Defensive medicine and obstetrics. JAMA 274(20): 1606-1610
Cardoso, S.H.; Coimbra, N.C.; Brandão, M.L. 1994: Defensive reactions evoked by activation of NMDA receptors in distinct sites of the inferior colliculus. Behavioural Brain Research 63(1): 17-24
Javorka, K.; Kulisek, V.; Calkovská, A. 1994: Defensive reflexes of the respiratory system in anaesthetized rabbits during high frequency jet ventilation. Experimental Physiology 79(6): 967-973
Gavagnin, M.; Marin, A.; Castelluccio, F.; Villani, G.; Cimino, G. 1994: Defensive relationships between Caulerpa prolifera and its shelled sacoglossan predators. Journal Of Experimental: 210
Trowbridge, C.D. 1994: Defensive responses and palatability of specialist herbivores: Predation on NE Pacific ascoglossan gastropods. Marine Ecology Progress Series 105(1-2): 61-70
King, S.M.; Cowey, A. 1992: Defensive responses to looming visual stimuli in monkeys with unilateral striate cortex ablation. Neuropsychologia 30(11): 1017-1024
Oliver, J.E.; Reinecke, A.J.; Reinecke, S.A. 1996: Defensive secretions of the grain stink bug Macchiademus diplopterus (Heteroptera: Lygaeidae). Suid Afrikaanse Tydskrif vir Natuurwetenskap en Tegnologie 15(4): 172-174
Mann, S.J.; James, G.D. 1998: Defensiveness and essential hypertension. Journal of Psychosomatic Research 45(2): 139-148
Isenberg, S.; Lehrer, P.; Hochron, S. 1997: Defensiveness and perception of external inspiratory resistive loads in asthma. Journal of Behavioral Medicine 20(5): 461-472,.
Boehme, H.; Teusch, L. 1997: Defensiveness in rating scales and psychotherapy outcome. Nervenarzt 68(11): 896-902
Kline, J.P.; Schwartz, G.E.; Fitzpatrick, D.F.; Hendricks, S.E. 1993: Defensiveness, anxiety and the amplitude/intensity function of auditory-evoked potentials. International Journal of Psychophysiology: Official Journal of the International Organization of Psychophysiology 15(1): 7-14
Jorgensen, R.S.; Abdul-Karim, K.; Kahan, T.A.; Frankowski, J.J. 1995: Defensiveness, cynical hostility and cardiovascular reactivity: a moderator analysis. PsychoTherapy and Psychosomatics 64(3-4): 156-161
Naruse, M.; Tanabe, A.; Sugaya, T.; Naruse, K.; Yoshimoto, T.; Seki, T.; Imaki, T.; Demura, R.; Murakami, K.; Demura, H. 1998: Deferential roles of angiotensin receptor subtypes in adrenocortical function in mice. Life Sciences 63(18): 1593-1598
Shalev, O.; Repka, T.; Goldfarb, A.; Grinberg, L.; Abrahamov, A.; Olivieri, N.F.; Rachmilewitz, E.A.; Hebbel, R.P. 1995: Deferiprone (L1) chelates pathologic iron deposits from membranes of intact thalassemic and sickle red blood cells both in vitro and in vivo. Blood 86(5): 2008-2013
al-Refaie, F.N.; Wonke, B.; Hoffbrand, A.V. 1994: Deferiprone-associated myelotoxicity. European Journal of Haematology 53(5): 298-301
Loebstein, R.; Diav-Citrin, O.; Atanackovic, G.; Olivieri, N.F.; Koren, G. 1997: Deferiprone-Induced Agranulocytosis : a Critical Review of Five Rechallenged Cases. Clinical Drug Investigation 13(6): 345-349
Autenrieth, I.B.; Bohn, E.; Ewald, J.H.; Heesemann, J. 1995: Deferoxamine B but not deferoxamine G1 inhibits cytokine production in murine bone marrow macrophages. Journal of Infectious Diseases 172(2): 490-496
Chenoufi, N.; Baffet, G.; Drénou, B.; Cariou, S.; Desille, M.; Clément, B.; Brissot, P.; Lescoat, G.; Loréal, O. 1998: Deferoxamine arrests in vitro the proliferation of porcine hepatocyte in G1 phase of the cell cycle. Liver 18(1): 60-66
Neumann, J.; Scholz, H. 1998: Deferoxamine blocks interactions of fluoride and carbachol in isolated mammalian cardiac preparations. European Journal of Pharmacology 350(2-3): 189-194
Drossos, G.; Lazou, A.; Panagopoulos, P.; Westaby, S. 1995: Deferoxamine cardioplegia reduces superoxide radical production in human myocardium. Annals of Thoracic Surgery 59(1): 169-172
Sanchez, C.; Serna, S.; Hernandez, J.; Valverde, E.; Nebro, S.; Martinez, C.; Villalobos, S. 1994: Deferoxamine collyrium in corneal hyphema. Farmacia Clinica 11(1): 93-95
Donfrancesco, A.; De-Bernardi, B.; Carli, M.; Mancini, A.; Nigro, M.; De-Sio, L.; Casale, F.; Bagnulo, S.; Helson, L.; Deb, G. 1995: Deferoxamine followed by cyclophosphamide, etoposide, carboplatin, thiotepa, induction regimen in advanced neuroblastoma: Preliminary results. European Journal of Cancer 31A(4): 612-615
Long, D.A.; Ghosh, K.; Moore, A.N.; Dixon, C.E.; Dash, P.K. 1996: Deferoxamine improves spatial memory performance following experimental brain injury in rats. Brain Research 717(1-2): 109-117
Blatt, J. 1994: Deferoxamine in children with recurrent neuroblastoma. Anticancer Research 14(5b): 2109-2112
Besbas, N.; Soylemezoglu, O.; Saatci, U.; Bakkaloglu, A.; Isimer, A.; Sayal, A. 1992: Deferoxamine infusion test in the diagnosis aluminium in childhood chronic renal failure. Cocuk Sagligi ve Hastaliklari Dergisi 35(4): 281-288
Palmer, C.; Roberts, R.L.; Bero, C. 1994: Deferoxamine posttreatment reduces ischemic brain injury in neonatal rats. Stroke 25(5): 1039-1045
Fantini, G.A.; Yoshioka, T. 1993: Deferoxamine prevents lipid peroxidation and attenuates reoxygenation injury in postischemic skeletal muscle. American Journal of Physiology 264(6 Pt 2): H1953-H1959
Hurn, P.D.; Koehler, R.C.; Blizzard, K.K.; Traystman, R.J. 1995: Deferoxamine reduces early metabolic failure associated with severe cerebral ischemic acidosis in dogs. Stroke 26(4): 688-94; Discussion 694-5
Katoh, S.; Toyama, J.; Kodama, I.; Kamiya, K.; Akita, T.; Abe, T. 1993: Deferoxamine reduces the reperfusion injury in isolated neonatal rabbit hearts after hypothermic preservation. Surgery Today 23(5): 424-429
Katoh, S.; Toyama, J.; Kodama, I.; Akita, T.; Abe, T. 1992: Deferoxamine, an iron chelator, reduces myocardial injury and free radical generation in isolated neonatal rabbit hearts subjected to global ischaemia-reperfusion. Journal of Molecular and Cellular Cardiology 24(11): 1267-1275
Bauer, C.; Marzi, I.; Larsen, R. 1997: Deferoxamine-conjugated hydroxyethyl starch reduces hepatic reperfusion injury after haemorrhagic shock. Anaesthesist 46(1): 53-56
Lee, Y.S.; Wurster, R.D. 1995: Deferoxamine-induced cytotoxicity in human neuronal cell lines: protection by free radical scavengers. Toxicology Letters 78(1): 67-71
McFarland, W.; Kahn, J.G.; Katzenstein, D.A.; Mvere, D.; Shamu, R. 1995: Deferral of blood donors with risk factors for HIV infection saves lives and money in Zimbabwe. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology: Official Publication of the International Retrovirology Association 9(2): 183-192
Bousses, P.; Chapuis, J-L. 1998: Deferred seasonal increase in testes weight under poor nutritional conditions in a sub-Antarctic population of rabbits (Oryctolagus cuniculus). Journal of Zoology (London) 245(3): 285-291
Adolfsson, J.; Rönström, L.; Löwhagen, T.; Carstensen, J.; Hedlund, P.O. 1994: Deferred treatment of clinically localized low grade prostate cancer: the experience from a prospective series at the Karolinska Hospital. Journal of Urology 152(5 Part 2): 1757-1760
Adolfsson, J. 1993: Deferred treatment of low grade stage T3 prostate cancer without distant metastases. Journal of Urology 149(2): 326-328; Discussion: 328-329
Greene, A.C.; Patel, B.K.; Sheehy, A.J. 1997: Deferribacter thermophilus gen. nov., sp. nov., a novel thermophilic manganese- and iron-reducing bacterium isolated from a petroleum reservoir. International Journal of Systematic Bacteriology 47(2): 505-509
Huang, D.X.; Gai, L.Y.; Wang, S.R.; Li, T.D.; Yang, T.S.; Zhi, G.; Du, L.S.; Li, L.H. 1992: Defibrase, a purified fibrinolytic protease from snake venom in acute myocardial infarction. Acta Cardiologica 47(5): 445-458
Ito, M.; Pride, H.P.; Zipes, D.P. 1993: Defibrillating shocks delivered to the heart impair efferent sympathetic responsiveness. Circulation 88(6): 2661-2673
Watts, D.D. 1995: Defibrillation by basic emergency medical technicians: Effect on survival. Annals of Emergency Medicine 26(5): 635-639
Macdonald, J.W.; Brewster, M.F.; Isles, C.G. 1993: Defibrillation by general practitioners: an audit of resuscitation in a Scottish rural practice. Scottish Medical Journal 38(3): 79-80
Jones, D.L.; Narayanan, N. 1998: Defibrillation depresses heart sarcoplasmic reticulum calcium pump: a mechanism of postshock dysfunction. American Journal of Physiology 274(1): H98-105
Tomassoni, G.; Newby, K.; Deshpande, S.; Axtell, K.; Sra, J.; Akhtar, M.; Natale, A. 1997: Defibrillation efficacy of commercially available biphasic impulses in humans. Importance of negative-phase peak voltage. Circulation 95(7): 1822-1826
Sweeney, R.J.; Gill, R.M.; Reid, P.R. 1997: Defibrillation efficacy using high-frequency switching to proportion current among simultaneous shock pathways. Journal of Cardiovascular Electrophysiology 8(3): 271-280
Guse, P.A.; Walcott, G.P.; Rollins, D.L.; Smith, W.M.; Ideker, R.E. 1992: Defibrillation electrode configurations developed from cardiac mapping that combine biphasic shocks with sequential timing. American Heart Journal 124(6): 1491-1500
Rigden, L.B.; Mitrani, R.D.; Wellman, H.N.; Klein, L.S.; Miles, W.M.; Zipes, D.P. 1996: Defibrillation shocks over epicardial patches produce sympathetic neural dysfunction in man. Journal of Cardiovascular Electrophysiology 7(5): 398-405
Li, H.G.; Jones, D.L.; Yee, R.; Klein, G.J. 1993: Defibrillation shocks produce different effects on Purkinje fibers and ventricular muscle: implications for successful defibrillation, refibrillation and postshock arrhythmia. Journal of the American College of Cardiology 22(2): 607-614
Obadia, J.F.; Janier, M.; Chevalier, P.; Bazillais, O.; Chassignolle, J.F.; Kirkorian, G.; Touboul, P. 1997: Defibrillation threshold and electrode configurations: an experimental study testing three configurations in twelve pigs. Journal of Cardiovascular Surgery 38(5): 495-499
Sweeney, R.J.; Gill, R.M.; Jones, J.L.; Reid, P.R. 1996: Defibrillation using a high-frequency series of monophasic rectangular pulses: Observations and model predictions. Journal of Cardiovascular Electrophysiology 7(2): 134-143
Barrington, W.W.; Deligonul, U.; Easley, A.R.; Windle, J.R. 1995: Defibrillator patch electrode constriction: An underrecognized entity. Annals of Thoracic Surgery 60(4): 1112-5; discussion 1115-6
Willems, H.L.; Kruse, J.; Geven, W.B.; Vis, P.; Monnens, L.A. 1995: Defibrination essential in the assay of ionized magnesium in mononuclear cells. European Journal of Clinical Chemistry and Clinical Biochemistry: Journal of the Forum of European Clinical Chemistry Societies 33(2): 103-104
Maisano, R.; Adamo, V.; Toscano, G.; Chiofalo, G.; Pergolizzi, S.; Scimone, A. 1997: Defibrotide in the prevention of venous irritation by vinorelbine administration. Anticancer Research 17(4a): 2775-2777
Ranieri, G.; De-Mitrio, V.; Petruzzellis, V.; Scaraggi, F.A.; Quaranta, D.; Dammacco, F. 1993: Defibrotide in the treatment of Raynaud's phenomenon in patients with progressive systemic sclerosis or essential mixed cryoglobulinemia. Current Therapeutic Research 53(1): 48-58
Yang, L.H.; Hoppensteadt, D.A.; Iqbal, O.; Fareed, J. 1996: Defibrotide mediated inhibition of serotonin, endothelin-I, thromboxane, and serum induced contraction of canine femoral and pulmonary arterial rings. Thrombosis Research 84(3): 167-177
Schröder, H. 1995: Defibrotide protects endothelial cells, but not L929 tumour cells, from tumour necrosis factor-alpha-mediated cytotoxicity. Journal of Pharmacy and Pharmacology 47(3): 250-252
Zhou, Q.; Chu, X.; Ruan, C. 1994: Defibrotide stimulates expression of thrombomodulin in human endothelial cells. Thrombosis and Haemostasis 71(4): 507-510
Frasca, G.M.; Martello, M.; Canova, C.; Isola, E.; Vangelista, A.; Bonomini, V. 1997: Defibrotide treatment and disease progression in patients with IgA nephropathy and impaired renal function at diagnosis. Clinical Drug Investigation 13(4): 185-191
Tubaro, M.; Mattioli, G.; Matta, F.; Cappello, C.; Natale, E.; Ricci, R.; Gerardi, P.; Milazzotto, F. 1993: Defibrotide versus heparin in the prevention of coronary reocclusion after thrombolysis in acute myocardial infarction. Cardiovascular Drugs and Therapy 7(5): 809-816
Battistoni, A.; Conati, G.; Leopardi, M.; Bonelli, U.; Cerruti, R.; Zinicola, N.; Brotzu, G.; Petruzzo, B.; Pibiri, L. 1993: Defibrotide versus pentoxifylline in patients with peripheral occlusive arterial disease. Acta Therapeutica 19(2): 181-190
Bianchi, G.; Barone, D.; Lanzarotti, E.; Tettamanti, R.; Porta, R.; Moltrasio, D.; Cedro, A.; Salvetti, L.; Mantovani, M.; Prino, G. 1993: Defibrotide, a single-stranded polydeoxyribonucleotide acting as an adenosine receptor agonist. European Journal of Pharmacology 238(2-3): 327-334
Bernhard, C.A.; Boillat, M.A. 1993: Deficiencies in air supply and distribution in offices. Sozial- und Praeventivmedizin 38(Suppl 2): S150-S151
McCulloch, C.A.; Knowles, G.C. 1993: Deficiencies in collagen phagocytosis by human fibroblasts in vitro: a mechanism for fibrosis?. Journal of Cellular Physiology 155(3): 461-471
Alexander, W.S.; Roberts, A.W.; Nicola, N.A.; Li, R.; Metcalf, D. 1996: Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietic receptor c-Mpl. Blood 87(6): 2162-2170
Chua-Lim, C.; Moore, R.B.; McCleary, G.; Shah, A.; Mankad, V.N. 1993: Deficiencies in school readiness skills of children with sickle cell anemia: a preliminary report. Southern Medical Journal 86(4): 397-402
Turnbull, G.I.; Charteris, J.; Wall, J.C. 1996: Deficiencies in standing weight shifts by ambulant hemiplegic subjects. Archives of Physical Medicine and Rehabilitation 77(4): 356-362
Singer, T.P.; Ramsay, R.R.; Ackrell, B.A. 1995: Deficiencies of NADH and succinate dehydrogenases in degenerative diseases and myopathies. Biochimica Et Biophysica Acta 1271(1): 211-219
Little, D.G.; Nigo, L.; Aiona, M.D. 1996: Deficiencies of current methods for the timing of epiphysiodesis. Journal of Pediatric Orthopedics 16(2): 173-179
Superti-Furga, A.; Raghunath, M.; Willems, P.J. 1992: Deficiencies of fibrillin and decorin in fibroblast cultures of a patient with neonatal Marfan syndrome. Journal of Medical Genetics 29(12): 875-878
Jerosch, J.; Heidjann, J.; Linnenbecker, S.; Thorwesten, L. 1996: Deficiencies of injury prophylaxis in inline-skating. Deutsche Zeitschrift fuer Sportmedizin 47(11-12): 570-573
Selby, C.D.; Sudlow, M.F. 1994: Deficiencies of management of spontaneous pneumothoraces. Scottish Medical Journal 39(3): 75-77
Mihailovic, M.; Matic, G.; Nikolic, V.; Avakumovic, D.; Zigic, B. 1994: Deficiency and surplus of selenium in pig diet. Veterinarski Glasnik 48(5-6): 459-465
Turan, B.; Koc, E.; Zaloglu, N. 1997: Deficiency and toxicity of selenium alter the acetylcholine stimulated contraction of isolated rabbit ileum. Trace Elements and Electrolytes 14(1): 13-18
Rasmussen, L.; Morris, S.; Wolitz, R.; Dowling, A.; Fessell, J.; Holodniy, M.; Merigan, T.C. 1994: Deficiency in antibody response to human cytomegalovirus glycoprotein gH in human immunodeficiency virus-infected patients at risk for cytomegalovirus retinitis. Journal of Infectious Diseases 170(3): 673-677
Zafeiriou, D.I.; Koletzko, B.; Mueller-Felber, W.; Paetzke, I.; Kueffer, G.; Jensen, M. 1995: Deficiency in complex IV (cytochrome c oxidase) of the respiratory chain, presenting as a leukodystrophy in two siblings with Leigh syndrome. Brain and Development 17(2): 117-121
Flickinger, K.S.; Carter, W.G.; Culp, L.A. 1992: Deficiency in integrin-mediated transmembrane signaling and microfilament stress fiber formation by aging dermal fibroblasts from normal and Down's syndrome patients. Experimental Cell Research 203(2): 466-475
Young, W.S.; Shepard, E.; Amico, J.; Hennighausen, L.; Wagner, K.U.; LaMarca, M.E.; McKinney, C.; Ginns, E.I. 1996: Deficiency in mouse oxytocin prevents milk ejection, but not fertility or parturition. Journal of Neuroendocrinology 8(11): 847-853
Kugiyama, K.; Yasue, H.; Ohgushi, M.; Motoyama, T.; Kawano, H.; Inobe, Y.; Hirashima, O.; Sugiyama, S. 1996: Deficiency in nitric oxide bioactivity in epicardial coronary arteries of cigarette smokers. Journal of the American College of Cardiology 28(5): 1161-1167
Yamamoto, A.; Takagi, H.; Kitamura, D.; Tatsuoka, H.; Nakano, H.; Kawano, H.; Kuroyanagi, H.; Yahagi, Y.; Kobayashi, S.; Koizumi, K.; Sakai, T.; Saito, K.; Chiba, T.; Kawamura, K.; Suzuki, K.; Watanabe, T.; Mori, H.; Shirasawa, T. 1998: Deficiency in protein L-isoaspartyl methyltransferase results in a fatal progressive epilepsy. Journal of Neuroscience: the Official Journal of the Society for Neuroscience 18(6): 2063-2074
Tapscott, S.J.; Thayer, M.J.; Weintraub, H. 1993: Deficiency in rhabdomyosarcomas of a factor required for MyoD activity and myogenesis. Science 259(5100): 1450-1453
Mikkola, H.; Syrjälä, M.; Rasi, V.; Vahtera, E.; Hämäläinen, E.; Peltonen, L.; Palotie, A. 1994: Deficiency in the A-subunit of coagulation factor XIII: two novel point mutations demonstrate different effects on transcript levels. Blood 84(2): 517-525
Cattaneo, M.; Lombardi, R.; Zighetti, M.L.; Gachet, C.; Ohlmann, P.; Cazenave, J.P.; Mannucci, P.M. 1997: Deficiency of (33P)2MeS-ADP binding sites on platelets with secretion defect, normal granule stores and normal thromboxane A2 production. Evidence that ADP potentiates platelet secretion independently of the formation of large platelet aggregates and thromboxane A2 production. Thrombosis and Haemostasis 77(5): 986-990
Hagervall, T.G.; Tuohy, T.M.; Atkins, J.F.; Björk, G.R. 1993: Deficiency of 1-methylguanosine in tRNA from Salmonella typhimurium induces frameshifting by quadruplet translocation. Journal of Molecular Biology 232(3): 756-765
Gregory, J.W.; Aynsley-Green, A.; Evans, B.A.; Hughes, I.A.; Werder, E.A.; Zachmann, M. 1993: Deficiency of 17-ketoreductase presenting before puberty. Hormone Research 40(4): 145-148
Bernier, F.P.; Snyder, F.F.; Mcleod, D.R. 1996: Deficiency of 5-oxoprolinase in an 8-year-old with developmental delay. Journal of Inherited Metabolic Disease 19(3): 367-368
Bessho, T.; Tano, K.; Kasai, H.; Nishimura, S. 1992: Deficiency of 8-hydroxyguanine DNA endonuclease activity and accumulation of the 8-hydroxyguanine in mutator mutant (mutM) of Escherichia coli. Biochemical and Biophysical Research Communications 188(1): 372-378
Oshitani, N.; Kitano, A.; Hara, J.; Suzuki, N.; Aoki, T.; Yasuda, K.; Watanabe, Y.; Obayashi, M.; Obata, A.; Nakamura, S. 1995: Deficiency of blood coagulation factor XIII in Crohn's disease. American Journal of Gastroenterology 90(7): 1116-1118
Manz, C.Y.; Nissen, C.; Wodnar-Filipowicz, A. 1996: Deficiency of CD34+ c-kit+ and CD34+38- hematopoietic precursors in aplastic anemia after immunosuppressive treatment. American Journal of Hematology 52(4): 264-274
Layward, L.; Allen, A.C.; Harper, S.J.; Hattersley, J.M.; Feehally, J. 1993: Deficiency of IgG subclass antibody response to tetanus toxoid associated with high serum IgA levels in IgA nephropathy. Clinical Nephrology 40(3): 131-136
Mazurov, A.V.; Vinogradov, D.V.; Khaspekova, S.G.; Krushinsky, A.V.; Gerdeva, L.V.; Vasiliev, S.A. 1996: Deficiency of P-selectin in a patient with grey platelet syndrome. European Journal of Haematology 57(1): 38-41
De Franceschi, L.; Fumagalli, L.; Olivieri, O.; Corrocher, R.; Lowell, C.A.; Berton, G. 1997: Deficiency of Src family kinases Fgr and Hck results in activation of erythrocyte K/Cl cotransport. Journal of Clinical Investigation 99(2): 220-227
Lowell, C.A.; Fumagalli, L.; Berton, G. 1996: Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions. Journal of Cell Biology 133(4): 895-910
Plioplys, A.V. 1995: Deficiency of a neuronal growth-sustaining factor in fibroblasts of patients with Alzheimer's disease. Journal of the Neurological Sciences 133(1-2): 24-30
Jingushi, S.; Hara, T.; Sugioka, Y. 1997: Deficiency of a parathyroid hormone fragment containing the midportion and 1,25-dihydroxyvitamin D in serum of patients with slipped capital femoral epiphysis. Journal of Pediatric Orthopedics 17(2): 216-219
Kim, E.; Lowenson, J.D.; Maclaren, D.C.; Clarke, S.; Young, S.G. 1997: Deficiency of a protein-repair enzyme results in the accumulation of altered proteins, retardation of growth, and fatal seizures in mice. Proceedings of the National Academy of Sciences of the United States of America 94(12): 6132-6137
Nagayoshi, A.; Matsuki, N.; Saito, H.; Tsukamoto, K.; Wakashima, M.; Kinoshita, M.; Yamanaka, M.; Teramoto, T. 1994: Deficiency of acyl CoA cholesterol acyl transferase activity in suncus liver. Journal of Biochemistry 115(5): 858-861
Scaloni, A.; Jones, W.; Pospischil, M.; Sassa, S.; Schneewind, O.; Popowicz, A.M.; Bossa, F.; Graziano, S.L.; Manning, J.M. 1992: Deficiency of acylpeptide hydrolase in small-cell lung carcinoma cell lines. Journal of Laboratory and Clinical Medicine 120(4): 546-552
Bucci, M.P.; Kapoula, Z.; Eggert, T.; Garraud, L. 1997: Deficiency of adaptive control of the binocular coordination of saccades in strabismus. Vision Research 37(19): 2767-2777
Yoshioka, K.; Higashi, Y.; Tanaka, K.; Aiyama, T.; Takayanagi, M.; Okumura, A.; Iwata, K.; Nagai, Y.; Kakumu, S. 1996: Deficiency of antibody response to hypervariable region of hepatitis C virus in patients with chronic hepatitis C. Journal of Hepatology 24(6): 649-657
Blumrich, M.; Pack, R.; Oesch, F.; Petzinger, E.; Steinberg, P. 1994: Deficiency of bile acid transport and synthesis in oval cells from carcinogen-fed rats. Hepatology 19(3): 722-727
Morita, J.; Thuy, L.P.; Sweetman, L. 1998: Deficiency of biotinyl-AMP synthetase activity in fibroblasts of patients with holocarboxylase synthetase deficiency. Molecular Genetics and Metabolism 64(4): 250-255
Kim, T.W.; Wu, K.; Black, I.B. 1995: Deficiency of brain synaptic dystrophin in human Duchenne muscular dystrophy. Annals of Neurology 38(3): 446-449
Isozaki, K.; Hirota, S.; Miyagawa, J.; Taniguchi, M.; Shinomura, Y.; Matsuzawa, Y. 1997: Deficiency of c-kit+ cells in patients with a myopathic form of chronic idiopathic intestinal pseudo-obstruction. American Journal of Gastroenterology 92(2): 332-334
Elfeldt, R.J.; Schmidt, D.; Thies, J.; Schröder, D.W.; Seiffert, P. 1994: Deficiency of cartilage in the segmental bronchi of a child: Congenital or acquired?. Annals of Thoracic Surgery 58(2): 565-567
Nieuwenhuijzen, G.A.; Meyer, M.P.; Hendriks, T.; Goris, R.J. 1995: Deficiency of complement factor C5 reduces early mortality but does not prevent organ damage in an animal model of multiple organ dysfunction syndrome. Critical Care Medicine 23(10): 1686-1693
Taylor, R.W.; Birch-Machin, M.A.; Schaefer, J.; Taylor, L.; Shakir, R.; Ackrell, B.A.; Cochran, B.; Bindoff, L.A.; Jackson, M.J.; Griffiths, P.; Turnbull, D.M. 1996: Deficiency of complex Ii of the mitochondrial respiratory chain in late-onset optic atrophy and ataxia. Annals of Neurology 39(2): 224-232
Hong, Y.-Soo; Kerr, D., S.; Liu, T.-Chung; Lusk, M.; Powell, B., R.; Patel, M., S. 1997: Deficiency of dihydrolipoamide dehydrogenase due to two mutant alleles (E340K and G101del): Analysis of a family and prenatal testing. Biochimica et Biophysica Acta 1362(2-3): 160-168
Matsumura, K.; Tomé, F.M.; Ionasescu, V.; Ervasti, J.M.; Anderson, R.D.; Romero, N.B.; Simon, D.; Récan, D.; Kaplan, J.C.; Fardeau, M. 1993: Deficiency of dystrophin-associated proteins in Duchenne muscular dystrophy patients lacking COOH-terminal domains of dystrophin. Journal of Clinical Investigation 92(2): 866-871
Wakabayashi, Y.; Yamada, E.; Yoshida, T.; Takahashi, H. 1994: Deficiency of endogenous arginine synthesis provokes hypertension by exhausting substrate arginine for nitric oxide synthesis. Biochemical and Biophysical Research Communications 205(2): 1391-1398
Kim, J.A.; Druse, M.J. 1996: Deficiency of essential neurotrophic factors in conditioned media produced by ethanol-exposed cortical astrocytes. Brain Research. Developmental Brain Research 96(1-2): 1-10
Veeramachaneni, D.N.; Smith, M.O.; Ellinwood, N.M. 1998: Deficiency of fucosidase results in acrosomal dysgenesis and impaired sperm maturation. Journal of Andrology 19(4): 444-449
Aoyagi, T.; Osanai, T.; Wada, T.; Kojima, F.; Nagai, M.; Harada, S.; Takeuchi, T.; Suzuki, A.; Nagai, Y. 1992: Deficiency of galactosidase activity in multiple organs in GM2-deficient mice. Journal of Clinical Biochemistry and Nutrition 13(3): 189-197
Kerb, R.; Brockmöller, J.; Reum, T.; Roots, I. 1997: Deficiency of glutathione S-transferases T1 and M1 as heritable factors of increased cutaneous UV sensitivity. Journal of Investigative Dermatology 108(2): 229-232
Shibuya, K.; Ninomiya, H.; Muraki, Y.; Nagasawa, T.; Abe, T. 1993: Deficiency of glycosyl phosphatidylinositol-anchored proteins in polymorphonuclear leukocytes from patients with paroxysmal nocturnal hemoglobinuria with low-grade hemolysis. International Journal of Hematology 58(1-2): 15-20
De Lord, C.; Tooze, J.A.; Saso, R.; Marsh, J.C.; Gordon-Smith, E.C. 1998: Deficiency of glycosylphosphatidyl inositol-anchored proteins in patients with aplastic anaemia does not affect response to immunosuppressive therapy. British Journal of Haematology 101(1): 90-93
Nageh, M.F.; Sandberg, E.T.; Marotti, K.R.; Lin, A.H.; Melchior, E.P.; Bullard, D.C.; Beaudet, A.L. 1997: Deficiency of inflammatory cell adhesion molecules protects against atherosclerosis in mice. Arteriosclerosis Thrombosis and Vascular Biology 17(8): 1517-1520
Frenzel, K.; Amann, G.; Lubec, B. 1998: Deficiency of laryngeal collagen type II in an infant with respiratory problems. Archives of Disease in Childhood 78(6): 557-559
Cremer, R.; Wahn, V. 1996: Deficiency of late complement components in patients with severe and recurrent meningococcal infections. European Journal of Pediatrics 155(8): 723-724
Hills, B.A.; Monds, M.K. 1998: Deficiency of lubricating surfactant lining the articular surfaces of replaced hips and knees. British Journal of Rheumatology 37(2): 143-147
Sunada, Y.; Bernier, S.M.; Kozak, C.A.; Yamada, Y.; Campbell, K.P. 1994: Deficiency of merosin in dystrophic dy mice and genetic linkage of laminin M chain gene to dy locus. Journal of Biological Chemistry 269(19): 13729-13732
García-Berrocal, J.R.; Vargas, J.A.; Ramírez-Camacho, R.A.; González, F.M.; Gea-Banacloche, J.C.; Vergara, J.; Durántez, A. 1997: Deficiency of naive T cells in patients with sudden deafness. Archives of Otolaryngology--Head and Neck Surgery 123(7): 712-717
Hayashi, T.; Hayakawa, Y.; Niiya, K.; Sakuragawa, N. 1994: Deficiency of natural anticoagulants. Japanese Journal of Electrophoresis 38(6): 397-402
Elghetany, M.T.; Peterson, B.; MacCallum, J.; Nelson, D.A.; Varney, J.F.; Sullivan, A.K.; Silverman, L.R.; Schiffer, C.A.; Davey, F.R.; Bloomfield, C.D. 1997: Deficiency of neutrophilic granule membrane glycoproteins in the myelodysplastic syndromes: A common deficiency in 216 patients studied by the Cancer and Leukemia Group B. Leukemia Research 21(9): 801-806
de Boer, J.; Meurs, H.; Coers, W.; Koopal, M.; Bottone, A.E.; Visser, A.C.; Timens, W.; Zaagsma, J. 1996: Deficiency of nitric oxide in allergen-induced airway hyperreactivity to contractile agonists after the early asthmatic reaction: An ex vivo study. British Journal of Pharmacology 119(6): 1109-1116
Zicha, D.; Dunn, G.A.; Segal, A.W. 1997: Deficiency of p67phox, p47phox or gp91phox in chronic granulomatous disease does not impair leucocyte chemotaxis or motility. British Journal of Haematology 96(3): 543-550
Didion, T.; Roggenkamp, R. 1990: Deficiency of peroxisome assembly in a mutant of the methylotrophic yeast Hansenula polymorpha. Current Genetics 17(2): 113-117
Cui, Y.; Zhang, Z.N.; Liu, E.K.; Pan, H.Z. 1993: Deficiency of phosphatidylinositol-linked membrane proteins on erythrocytes of different subpopulations in paroxysmal nocturnal hemoglobinuria. Chinese Medical Journal 106(5): 323-330
Lee, M.H.; Vosburgh, E.; Anderson, K.; McDonagh, J. 1993: Deficiency of plasma plasminogen activator inhibitor 1 results in hyperfibrinolytic bleeding. Blood 81(9): 2357-2362
Yoshida, H.; Satoh, K.; Koyama, M.; Hiramoto, M.; Takamatsu, S. 1996: Deficiency of plasma platelet-activating factor acetylhydrolase: roles of blood cells. American Journal of Hematology 53(3): 158-164
Snaith, H.A.; Armstrong, C.G.; Guo, Y.; Kaiser, K.; Cohen, P.T. 1996: Deficiency of protein phosphatase 2A uncouples the nuclear and centrosome cycles and prevents attachment of microtubules to the kinetochore in Drosophila microtubule star (mts) embryos. Journal of Cell Science 109: 3001-3012
Zhou, Y.P.; Ostenson, C.G.; Ling, Z.C.; Grill, V. 1995: Deficiency of pyruvate dehydrogenase activity in pancreatic islets of diabetic GK rats. Endocrinology 136(8): 3546-3551
Hansikova, H.; Zeman, J.; Klement, P.; Technikova-Dobrova, Z.; Houstkova, H.; Houstek, J.; Papa, S. 1993: Deficiency of pyruvate dehydrogenase complex in tissues of an eight month old infant. Biochemistry and Molecular Biology International 31(6): 1157-1166
Baranowski, W.; Dirheimer, G.; Jakowicki, J.A.; Keith, G. 1994: Deficiency of queuine, a highly modified purine base, in transfer RNAs from primary and metastatic ovarian malignant tumors in women. Cancer Research 54(16): 4468-4471
Morris, A.A.; Leonard, J.V.; Brown, G.K.; Bidouki, S.K.; Bindoff, L.A.; Woodward, C.E.; Harding, A.E.; Lake, B.D.; Harding, B.N.; Farrell, M.A.; Bell, J.E.; Mirakhur, M.; Turnbull, D.M. 1996: Deficiency of respiratory chain complex i is a common cause of Leigh disease. Annals of Neurology 40(1): 25-30
Almasan, A.; Yin, Y.; Kelly, R.E.; Lee, E.Y.; Bradley, A.; Li, W.; Bertino, J.R.; Wahl, G.M. 1995: Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis. Proceedings of the National Academy of Sciences of the United States of America 92(12): 5436-5440
Watanabe, C.; Kasanuma, Y.; Satoh, H. 1997: Deficiency of selenium enhances the K+-induced release of dopamine in the striatum of mice. Neuroscience Letters 236(1): 49-52
Benders, A.A.G.M.; Timmermans, J.A.H.; Oosterhof, A.; Ter Laak, H.J.; Van Kuppevelt, T.H.M.S.M.; Evers, R.A.; Veerkamp, J.H. 1993: Deficiency of sodium/potassium-ATPase and sarcoplasmic reticulum calcium-ATPase in skeletal muscle and cultured muscle cells of myotonic dystrophy patients. Biochemical Journal 293(1): 269-274
Starostik, P.; Manshouri, T.; O'Brien, S.; Freireich, E.; Kantarjian, H.; Haidar, M.; Lerner, S.; Keating, M.; Albitar, M. 1998: Deficiency of the ATM protein expression defines an aggressive subgroup of B-cell chronic lymphocytic leukemia. Cancer Research 58(20): 4552-4557
Dianzani, U.; Bragardo, M.; DiFranco, D.; Alliaudi, C.; Scagni, P.; Buonfiglio, D.; Redoglia, V.; Bonissoni, S.; Correra, A.; Dianzani, I.; Ramenghi, U. 1997: Deficiency of the Fas apoptosis pathway without Fas gene mutations in pediatric patients with autoimmunity/lymphoproliferation. Blood 89(8): 2871-2879
Takeda, J.; Miyata, T.; Kawagoe, K.; IIda, Y.; Endo, Y.; Fujita, T.; Takahashi, M.; Kitani, T.; Kinoshita, T. 1993: Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria. Cell 73(4): 703-711
Lowell, C.A.; Niwa, M.; Soriano, P.; Varmus, H.E. 1996: Deficiency of the Hck and Src tyrosine kinases results in extreme levels of extramedullary hematopoiesis. Blood 87(5): 1780-1792
Bakker, H.D.; Scholte, H.R.; Van den Bogert, C.; Ruitenbeek, W.; Jeneson, J.A.; Wanders, R.J.; Abeling, N.G.; Dorland, B.; Sengers, R.C.; Van Gennip, A.H. 1993: Deficiency of the adenine nucleotide translocator in muscle of a patient with myopathy and lactic acidosis: a new mitochondrial defect. Pediatric Research 33(4 Part 1): 412-417
Wulffraat, N.M.; Sanders, E.A.; Fijen, C.A.; Hannema, A.; Kuis, W.; Zegers, B.J. 1994: Deficiency of the beta subunit of the eighth component of complement presenting as arthritis and exanthem. Arthritis and Rheumatism 37(11): 1704-1706
Culiat, C.; Stubbs, L.J.; Woychik, R.P.; Russell, L.B.; Johnson, D.K.; Rinchik, E.M. 1995: Deficiency of the beta-3 subunit of the type A gamma-aminobutyric acid receptor causes cleft palate in mice. Nature Genetics 11(3): 344-346
Hirose, E.; Matsumoto, J. 1993: Deficiency of the gene B impairs differentiation of melanophores in the medaka fish, Oryzias latipes: Fine structure studies. Pigment Cell Research 6(1): 45-51
Boonen, S.; Lesaffre, E.; Aerssens, J.; Pelemans, W.; Dequeker, J.; Bouillon, R. 1996: Deficiency of the growth hormone-insulin-like growth factor-I axis potentially involved in age-related alterations in body composition. Gerontology 42(6): 330-338
Gans, H.A.; Arvin, A.M.; Galinus, J.; Logan, L.; DeHovitz, R.; Maldonado, Y. 1998: Deficiency of the humoral immune response to measles vaccine in infants immunized at age 6 months. JAMA 280(6): 527-532
Huizing, M.; Ruitenbeek, W.; Thinnes, F.P.; DePinto, V.; Wendel, U.; Trijbels, F.J.; Smit, L.M.; ter Laak, H.J.; van den Heuvel, L.P. 1996: Deficiency of the voltage-dependent anion channel: a novel cause of mitochondriopathy. Pediatric Research 39(5): 760-765
Gaetani, P.; Tartara, F.; Tancioni, F.; Rodriguez y Baena, R.; Casari, E.; Alfano, M.; Grazioli, V. 1997: Deficiency of total collagen content and of deoxypyridinoline in intracranial aneurysm walls. Febs Letters 404(2-3): 303-306
Anderson, B.B.; Corda, L.; Perry, G.M.; Pilato, D.; Giuberti, M.; Vullo, C. 1995: Deficiency of two red-cell flavin enzymes in a population in Sardinia: was glutathione reductase deficiency specifically selected for by malaria?. American Journal of Human Genetics 57(3): 674-681
Enomoto, T.; Asano, Y. 1994: Deficiency of tyrosine phosphorylation in a Balb/c 3T3 cell variant hypersensitive to phorbol ester-induced cell transformation. Carcinogenesis 15(6): 1093-1097
Lancellotti, L.; D'orazio, C.; Mastella, G.; Mazzi, G.; Lippi, U. 1996: Deficiency of vitamins E and A in cystic fibrosis is independent of pancreatic function and current enzyme and vitamin supplementation. European Journal of Pediatrics 155(4): 281-285
Labouesse, M. 1997: Deficiency screen based on the monoclonal antibody MH27 to identify genetic loci required for morphogenesis of the Caenorhabditis elegans embryo. Developmental Dynamics: An Official Publication of the American Association of Anatomists 210(1): 19-32
Chen, F.L.; Kung, J.T. 1996: Deficient CD4+ T cell proliferation in the class 1 MHC-restricted 2C TCR-transgenic mouse. Journal of Immunology 156(6): 2036-2044
Sandor, Z.; Bredberg, A. 1995: Deficient DNA repair of triple helix-directed double psoralen damage in human cells. Febs Letters 374(2): 287-291
Prieto-Alamo, M.J.; Laval, F. 1998: Deficient DNA-ligase activity in the metabolic disease tyrosinemia type I. Proceedings of the National Academy of Sciences of the United States of America 95(21): 12614-12618
Cantwell, M.J.; Hua, T.; Zvaifler, N.J.; Kipps, T.J. 1997: Deficient Fas ligand expression by synovial lymphocytes from patients with rheumatoid arthritis. Arthritis and Rheumatism 40(9): 1644-1652
Fló, J.; Roux, M.E.; Massouh, E. 1994: Deficient induction of the immune response to oral immunization with cholera toxin in malnourished rats during suckling. Infection and Immunity 62(11): 4948-4954
Yeo, T.T.; Yang, T.; Massa, S.M.; Zhang, J.S.; Honkaniemi, J.; Butcher, L.L.; Longo, F.M. 1997: Deficient LAR expression decreases basal forebrain cholinergic neuronal size and hippocampal cholinergic innervation. Journal of Neuroscience Research 47(3): 348-360
Vingerhoets, J.; Vanham, G.; Kestens, L.; Penne, G.; Leroux-Roels, G.; Gigase, P. 1994: Deficient T-cell responses in non-responders to hepatitis B vaccination: absence of TH1 cytokine production. Immunology Letters 39(2): 163-168
Paulus, W.J.; Bronzwaer, J.G.; Felice, H.; Kishan, N.; Wellens, F. 1992: Deficient acceleration of left ventricular relaxation during exercise after heart transplantation. Circulation 86(4): 1175-1185
Reichert, F.; Rotshenker, S. 1996: Deficient activation of microglia during optic nerve degeneration. Journal of Neuroimmunology 70(2): 153-161
Ostenson, C.G.; Abdel-Halim, S.M.; Rasschaert, J.; Malaisse-Lagae, F.; Meuris, S.; Sener, A.; Efendic, S.; Malaisse, W.J. 1993: Deficient activity of FAD-linked glycerophosphate dehydrogenase in islets of GK rats. Diabetologia 36(8): 722-726
Yoshikawa, H.; Fukuda, K.; Wanaka, Y.; Kasamatsu, K.; Baba, A.; Nishio, I.; Masuyama, Y. 1994: Deficient activity of stimulatory nucleotide-binding regulatory protein in lymphocytes from patients with essential hypertension. American Journal of Hypertension 7(8): 713-716
Furlan, M.; Robles, R.; Solenthaler, M.; Wassmer, M.; Sandoz, P.; Lämmle, B. 1997: Deficient activity of von Willebrand factor-cleaving protease in chronic relapsing thrombotic thrombocytopenic purpura. Blood 89(9): 3097-3103
Wang, K.Y.; Juriloff, D.M.; Diewert, V.M. 1995: Deficient and delayed primary palatal fusion and mesenchymal bridge formation in cleft lip-liable strains of mice. Journal of Craniofacial Genetics and Developmental Biology 15(3): 99-116
Saijo, S.; Bucana, C.D.; Ramirez, K.M.; Cox, P.A.; Kripke, M.L.; Strickland, F.M. 1995: Deficient antigen presentation and Ts induction are separate effects of ultraviolet irradiation. Cellular Immunology 164(2): 189-202
Grabbe, S.; Gallo, R.L.; Lindgren, A.; Granstein, R.D. 1993: Deficient antigen presentation by Langerhans cells from athymic (nu/nu) mice. Restoration with thymic transplantation or administration of cytokines. Journal of Immunology 151(7): 3430-3439
Lepesant, H.; Pierres, M.; Naquet, P. 1995: Deficient antigen presentation by thymic epithelial cells reveals differential induction of T cell clone effector functions by CD28-mediated costimulation. Cellular Immunology 161(2): 279-287
Rouas-Freiss, N.; Housseau, F.; Bidart, J.M.; Bonnerot, C.; Amigorena, S.; Guillet, J.G.; Bellet, D. 1993: Deficient antigen processing of a protein quaternary structure can be overcome by receptor-mediated uptake. European Journal of Immunology 23(12): 3335-3344
Kovats, S.; Nepom, G.T.; Coleman, M.; Nepom, B.; Kwok, W.W.; Blum, J.S. 1995: Deficient antigen-presenting cell function in multiple genetic complementation groups of type II bare lymphocyte syndrome. Journal of Clinical Investigation 96(1): 217-223
Loeliger, A.E.; Rijkers, G.T.; Aerts, P.; Been-Tiktak, A.; Hoepelman, A.I.; van Dijk, H.; Borleffs, J.C. 1995: Deficient antipneumococcal polysaccharide responses in HIV-seropositive patients. Fems Immunology and Medical Microbiology 12(1): 33-41
Manoach, D.S.; Weintraub, S.; Daffner, K.R.; Scinto, L.F. 1997: Deficient antisaccades in the social-emotional processing disorder. Neuroreport 8(4): 901-905
Canitrot, Y.; Frit, P.; Salles, B. 1997: Deficient apoptotic process in cisplatin-resistant L1210 cells cannot account for the cellular response to various drug treatments. Biochemical and Biophysical Research Communications 234(3): 573-577
Takahashi, M.; Takeda, J.; Hirose, S.; Hyman, R.; Inoue, N.; Miyata, T.; Ueda, E.; Kitani, T.; Medof, M.E.; Kinoshita, T. 1993: Deficient biosynthesis of N-acetylglucosaminyl-phosphatidylinositol, the first intermediate of glycosyl phosphatidylinositol anchor biosynthesis, in cell lines established from patients with paroxysmal nocturnal hemoglobinuria. Journal of Experimental Medicine 177(2): 517-521
Ye, C.; Ho-Pao, C.L.; Kanazirska, M.; Quinn, S.; Seidman, C.E.; Seidman, J.G.; Brown, E.M.; Vassilev, P.M. 1997: Deficient cation channel regulation in neurons from mice with targeted disruption of the extracellular Ca2+-sensing receptor gene. Brain Research Bulletin 44(1): 75-84
Weder, B.; Seitz, R.J. 1994: Deficient cerebral activation pattern in stroke recovery. Neuroreport 5(4): 457-460
Ikeda, T.; Fujii, K.; Tamura, S.; Inoue, A.; Ogawa, K. 1996: Deficient coagulation factor XI in a child with preretinal hemorrhage. Rinsho Ganka 50(4): 589-592
Poole, C.J.; Hill, D.J.; Christie, J.L.; Birch, J. 1997: Deficient colour vision and interpretation of histopathology slides: cross sectional study. BMJ 315(7118): 1279-1281
Strupp, B.J.; Bunsey, M.; Levitsky, D.A.; Hamberger, K. 1994: Deficient cumulative learning: An animal model of retarded cognitive development. Neurotoxicology and Teratology 16(1): 71-79
Kumar, A.; Yang, Y.L.; Flati, V.; Der, S.; Kadereit, S.; Deb, A.; Haque, J.; Reis, L.; Weissmann, C.; Williams, B.R. 1997: Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB. EMBO Journal 16(2): 406-416
Missias, A.C.; Mudd, J.; Cunningham, J.M.; Steinbach, J.H.; Merlie, J.P.; Sanes, J.R. 1997: Deficient development and maintenance of postsynaptic specializations in mutant mice lacking an 'adult' acetylcholine receptor subunit. Development 124(24): 5075-5086
Kasugai, T.; Oguri, K.; Jippo-Kanemoto, T.; Morimoto, M.; Yamatodani, A.; Yoshida, K.; Ebi, Y.; Isozaki, K.; Tei, H.; Tsujimura, T. 1993: Deficient differentiation of mast cells in the skin of mi/mi mice. Usefulness of in situ hybridization for evaluation of mast cell phenotype. American Journal of Pathology 143(5): 1337-1347
Pilarski, L.M.; Szczepek, A.J.; Belch, A.R. 1997: Deficient drug transporter function of bone marrow-localized and leukemic plasma cells in multiple myeloma. Blood 90(9): 3751-3759