EurekaMag.com logo
+ Translate

Dehydroepiandrosterone sulphate, body fat distribution and insulin in obese men


, : Dehydroepiandrosterone sulphate, body fat distribution and insulin in obese men. International Journal of Obesity and Related Metabolic Disorders 19(1): 57-60

Sex steroid hormones may be involved in determining body fat distribution in men. Recent evidence suggests that insulin may be an important regulator of sex hormones metabolism in men. Few data, however, are available on the relationship of dehydroepiandrosterone sulphate (DHEA-SO-4), a major secretory product of the adrenal gland, to regional distribution of body fat or to insulin levels in men. We therefore examined the association of DHEA-SO-4, total testosterone and free testosterone to waist-to-hip ratio (WHR) and to subscapular-to-triceps ratio (STR) in 34 obese, otherwise healthy men. In addition, we examined the relation between these sex steroid hormones and insulin response to an oral glucose tolerance test. DHEA-SO-4 was significantly positively related to STR and significantly negatively related to insulin area. These associations remained significant after adjustment for age and obesity. Using multiple linear regression, DHEA-SO-4 was independently related to both STR and insulin area. Without claiming any causality in the observed associations, we conclude that, in obese men, high DHEA-SO-4 levels are related to centralized adiposity, while low DHEA-SO-4 levels are related to hyperinsulinemia.

(PDF 0-2 workdays service)

Order PDF Full Text

Close
Close

Click here to order any other PDF Full Text


Accession: 008425863

PMID: 7719392

PDF Full Text: Submit


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Other references

T.H. Pearce; B.E. Gorman; T.C. Birkett, 1977: The relationship between major element chemistry and tectonic environment of basic and intermediate volcanic rocks. This work reports the preliminary results of a study of the relationship between tectonic environment and major element chemistry of volcanic rocks. Using a file of 8400 analyses of rocks of varying ages and geographic distribution it has been fou...

Neumann, K. H.; Menzel, S.; Peuschel, B.; Vogt, P.; Brunkhorst, R., 1993: Long-term function and morphology of rat kidneys denervated by autotransplantation. Nephrology Dialysis Transplantation 8(9): 900-901

Krasko, A.; Schröder, H.C.; Batel, R.; Grebenjuk, V.A.; Steffen, R.; Müller, I.M.; Müller, W.E.G., 2002: Iron induces proliferation and morphogenesis in primmorphs from the marine sponge Suberites domuncula. Dissociated cells from marine demosponges retain their proliferation capacity if they are allowed to form special aggregates, the primmorphs. On the basis of incorporation studies and septin gene expression, we show that Fe3+ ions are required for...

Daubenmire, R., 1978: Plant geography with special reference to North America. A textbook organized in two major parts. The first part summarizes the more important concepts of floristic plant geography. The second part (most of the book) is ecological in its approach and characterizes the vegetation types of North America a...

Garcia, N.H.; Garvin, J.L., 1995: ANF and angiotensin II interact via kinases in the proximal straight tubule. Atrial natriuretic factor (ANF) inhibits fluid absorption (J-v) in the proximal straight tubule (PST) only after stimulation with angiotensin II (ANG II). To investigate ANF's dependency on ANG II for transport inhibition, we blocked and mimi...

Koppanyi, T.; Avery, M.A., 1966: Species differences and the clinical trial of new drugs: a review. In recent years a great deal of new information has been published on the effects of drugs and poisons on different strains of the same species and on different species of animals. Strains and different species, including Homo, may differ in the r...

Burris, R. H., 1994: Comparative study of the response of Azotobacter vinelandii and Acetobacter diazotrophicus to changes in pH. Curves were established for the pH response of respiration on eleven substrates by Azotobacter vinelandii and Acetobacter diazotrophicus. With every substrate the optimal pH for A. diazotrophicus was lower than for A. vinelandii. The optimal hydro...

Walton, A. C., 1935: The Nematoda as parasites of Amphibia 2. The author cites and provides specific measurements of parasitic nematodes of superfamilies Filaroidea, Spi-ruroidea, Stengyloidea, Dioctophymoidea, and Trichinel-loidea that have been descr. from amphibian hosts. A host list is given together wit...

Freytag S.; Mette W.; Fuersich F. T., 1996: Jurassic paleoecological controls on the benthos of southern Tunisia. Zentralblatt fuer Geologie und Palaeontologie, Teil I: Allgemeine, Angewandte, Regionale und Historische Geologie: 3-4, Pages 471-486. 1996.

ROYCE, P.C.; SAYERS, G., 1958: Corticotropin releasing activity of a pepsin labile factor in the hypothalamus. Ability of acid extracts of calf hypothalamus (stalk-median eminence area) to induce adrenal ascorbic acid depletion in rats with median eminence lesions is attributable in large measure to a pepsin labile factor distinct from ACTH and from vasopr...