EurekaMag.com logo
+ Site Statistics
References:
53,869,633
Abstracts:
29,686,251
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Diagnosis of intractable gastric ulcer by endoscopic ultrasonography



Diagnosis of intractable gastric ulcer by endoscopic ultrasonography



Stomach & Intestine 27(12): 1413-1421



We studied the findings of intractable gastric ulcer by endoscopic ultrasonography (EUS). It was possible to diagnose the depth of ulcer by EUS. The echo pattern in Ul-IV were subclassified into six types, that is Hn, Bsub n Bn, Hf, Bsub f, Bf. We measured the diameter of ulcer and ulcer area in EUS pictures by using a video processor, EXCEL. In this report, we observed the endoscopic cumulative healing rate in 140 patients with active gastric ulcer, and compared the healing rate of H-2 blocker with that of proton pump inhibitor. Ninety-four patients with gastric ulcer were treated with H-2 blockers. The endoscopic cumulative healing rates after 8 weeks of H-2 blocker treatment were 89% in Ul-II ulcer, 82% in Ul-III ulcer, and 64% in Ul-IV ulcer. In Ul-IV ulcer, the lowest cumulative healing rate among 6 echo patterns during the same periods was 33% in the Bf type under H-2 blocker treatment. The healing rate in an ulcer area larger than 400 mm-2 was below 50%. Likewise, the contraction rate of the ulcer area in the healed group was sigificantly lower than that in the non-healed group (p lt 0.001). Thus the EUS findings of intractable gastric ulcer were found to be Ul-IV, Bf type in the internal echo pattern, ulcer area larger than 400 mm-2, and poor contraction rate of the ulcer area. Histologically, this type of gastric ulcer had thick, wide, dense fibrosis, and fusion between the muscularis mucosae and the proper muscle layer. All 46 patients in the omeprazole treatment group had achieved endoscopic healing within 8 weeks. Between H-2 blocker and proton pump inhibitor treatment group, there was no difference in ulcer depth, echo pattern, and ulcer area. When endoscopic healing was verified in patients with intractable gastric ulcer by omeprazole, a comparatively large ulcer area in EUS picture remained and patients relapsed a short time after discontinuance of omeprazole. It was suggested that internal ulcer healing should be maintained duirng gastric ulcer treatment.

(PDF emailed within 1 workday: $29.90)

Accession: 008460226

Download citation: RISBibTeXText



Related references

Evaluation of endoscopic ultrasonography on the histological diagnosis of gastric ulcer. Current Therapeutic Research 40(3): 604-612, 1986

A study on the diagnosis of gastric ulcer by endoscopic ultrasonography eus the first report a fundamental investigation using artificial ulcers of dog. Gastroenterological Endoscopy 30(10): 2197-2208, 1988

Characteristics and prognosis of intractable gastric ulcer determined by endoscopic observations of ulcer scars. Stomach & Intestine 27(12): 1403-1411, 1992

A trial for judgment of gastric ulcer healing using endoscopic ultrasonography eus for the purpose of establishing a new classification of the healing process of gastric ulcer. Gastroenterological Endoscopy 29(9): 1991-1998, 1987

Endoscopic studies on intractable gastric ulcer. Stomach & Intestine 27(12): 1393-1401, 1992

Endoscopic ultrasonography in the diagnosis of the depth of gastric cancerous invasion differential diagnosis between cancerous invasion and fibrosis of the co existing ulcer. Gastroenterological Endoscopy 31(5): 1141-1155, 1989

Clinical and conventional endoscopic studies of gastric ulcer on the evaluation of the depth using endoscopic ultrasonography endoscopic findings of the different depth and its course. Gastroenterological Endoscopy 34(4): 800-811, 1992

Endoscopic change of intractable gastric ulcer after eight-weeks' treatment. Stomach & Intestine 28(4): 263-269, 1993

Quantification of gastric ulcer healing by endoscopic ultrasonography. Gastrointestinal Endoscopy 36(2): 116-122, 1990

Evaluating gastric ulcer healing by endoscopic ultrasonography. Endoscopy 26(9): 798-799, 1994

An analysis of the structure of gastric ulcer by endoscopic ultrasonography. Nihon Shokakibyo Gakkai Zasshi 84(2): 187-198, 1987

Gastric ulcer: can endoscopic ultrasonography predict healing?. Gastrointestinal Endoscopy Clinics of North America 5(3): 675-682, 1995

Endoscopic ultrasonography in the assessment of the depth of gastric ulcer. Stomach & Intestine (Tokyo) 23(5): 495-501, 1988

Is endoscopic ultrasonography (EUS) needed for deciding the indication for endoscopic submucosal dissection (ESD) of early gastric carcinoma? - the significance of diagnosis of the invasive depth and lymphnode metastasis of gastric carcinoma by EUS. Stomach and Intestine (Tokyo) 40(5): 779-790, 2005

Sequential observation of gastric ulcer healing by endoscopic ultrasonography. Scandinavian Journal of Gastroenterology 29(7): 665-670, 1994