+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Differential sensitivity of human visual cortex to faces, letterstrings, and textures: a functional magnetic resonance imaging study



Differential sensitivity of human visual cortex to faces, letterstrings, and textures: a functional magnetic resonance imaging study



Journal of Neuroscience 16(16): 5205-5215



Twelve normal subjects viewed alternating sequences of unfamiliar faces, unpronounceable nonword letterstrings, and textures while echoplanar functional magnetic resonance images were acquired in seven slices extending from the posterior margin of the splenium to near the occipital pole. These stimuli were chosen to elicit initial category-specific processing in extrastriate cortex while minimizing semantic processing. Overall, faces evoked more activation than did letterstrings. Comparing hemispheres, faces evoked greater activation in the right than the left hemisphere, whereas letterstrings evoked greater activation in the left than the right hemisphere. Faces primarily activated the fusiform gyrus bilaterally, and also activated the right occipitotemporal and inferior occipital sulci and a region of lateral cortex centered in the middle temporal gyrus. Letterstrings primarily activated the left occipitotemporal and inferior occipital sulci. Textures primarily activated portions of the collateral sulcus. In the left hemisphere, 9 of the 12 subjects showed a characteristic pattern in which faces activated a discrete region of the lateral fusiform gyrus, whereas letterstrings activated a nearby region of cortex within the occipitotemporal and inferior occipital sulci. These results suggest that different regions of ventral extrastriate cortex are specialized for processing the perceptual features of faces and letterstrings, and that these regions are intermediate between earlier processing in striate and peristriate cortex, and later lexical, semantic, and associative processing in downstream cortical regions.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 008475305

Download citation: RISBibTeXText

PMID: 8756449

DOI: 10.1523/jneurosci.16-16-05205.1996


Related references

Functional magnetic resonance imaging as a tool for investigating amblyopia in the human visual cortex: a pilot study. Journal of Aapos 6(5): 300-308, 2002

Effects of long-term potentiation in the human visual cortex: a functional magnetic resonance imaging study. Neuroreport 16(18): 1977-1980, 2005

The processing of visual shape in the cerebral cortex of human and nonhuman primates: a functional magnetic resonance imaging study. Journal of Neuroscience 24(10): 2551-2565, 2004

A case of persistent visual hallucinations of faces following LSD abuse: a functional Magnetic Resonance Imaging study. Neurocase 16(2): 106-118, 2010

Functional magnetic resonance imaging of the human primary visual cortex during visual stimulation. Nippon Ganka Gakkai Zasshi 99(5): 612-617, 1995

Retinotopic mapping of the peripheral visual field to human visual cortex by functional magnetic resonance imaging. Human Brain Mapping 33(7): 1727-1740, 2012

Functional magnetic resonance imaging of the primary visual cortex: evaluation of human afferent visual system. Japanese Journal of Ophthalmology 39(3): 302-308, 1995

Functional mapping of the human visual cortex by magnetic resonance imaging. Science 254(5032): 716-719, 1991

Hue Selectivity in Human Visual Cortex Revealed by Functional Magnetic Resonance Imaging. Cerebral Cortex 25(12): 4869-4884, 2015

Functional magnetic resonance imaging of brightness induction in the human visual cortex. Neuroreport 16(12): 1335-1338, 2005

Opposing effects of contextual surround in human early visual cortex revealed by functional magnetic resonance imaging with continuously modulated visual stimuli. Journal of Neuroscience 30(9): 3264-3270, 2010

Retinotopic representations of human visual cortex revealed by functional magnetic resonance imaging. Chinese Journal of Ophthalmology 43(12): 1097-1105, 2007

Functional magnetic resonance imaging evidence for binocular interactions in human visual cortex. Experimental Brain Research 145(3): 334-339, 2002

A functional magnetic resonance imaging investigation of visual hallucinations in the human striate cortex. Behavioral and Brain Functions 12(1): 31, 2016

Colour tuning in human visual cortex measured with functional magnetic resonance imaging. Nature 388(6637): 68-71, 1997