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Estrogen receptor in dysplastic and malignant cervical tissue: Expression, localisation and prognostic significance



Estrogen receptor in dysplastic and malignant cervical tissue: Expression, localisation and prognostic significance



Medical Science Research 24(8): 523-524



To investigate the estrogen receptor expression of cells in cervical carcinoma without malignant glandular elements, 34 cases were investigated. The average age at diagnosis was 41.8 years (17-72 years). Nucleosolic estrogen receptors were measured in all of these cases. Measurements were made using a dextran-coated charcoal technique involving a seven point Scatchard's plot analysis. 25 cases of cervical intraepithelial neoplasia, seven human papillomavirus and two microinvasive cervical carcinoma tissues were analysed. There was a correlation between menopausal status, histotype and histological grade with estrogen receptor status.

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