+ Site Statistics
PDF Full Text:
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn
Follow on LinkedInFollow on Tumblr

+ Translate

Experimental mandibular regrowth by distraction osteogenesis: Long-term results

, : Experimental mandibular regrowth by distraction osteogenesis: Long-term results. Archives of Otolaryngology Head and Neck Surgery 119(5): 511-516

The use of gradual distraction to grow bone (distraction osteogenesis) has gained widespread orthopedic acceptance, but has only recently been applied to craniofacial skeletal defects. The use of bifocal distraction osteogenesis to fill experimental segmental mandibular defects with regenerate bone was recently reported. Though all canines in that study demonstrated normal oromandibular function, they were observed for only 4 weeks following defect closure. The study that is now reported describes the long-term (12-month) functional, morphologic, and biomechanical results when bifocal distraction osteogenesis was applied to the same model. In this long-term study, three canines had 2.5-cm unilateral segmental mandibular body defects filled with structurally stable bone using bifocal distraction osteogenesis. These dogs exhibited normal oromandibular function for 1 year following segment regrowth and external fixator removal. Macroscopic and histologic evaluation of the regrown segments revealed a re-formation of the cortical and medullary architecture. Stress testing demonstrated the average ultimate strength of the regrown segment at 53 MPa, which corresponded to 77% +- 5.7% of normal mandibular bone. The data suggest that clinical trials applying this technique to segmental mandibular reconstruction are warranted.

(Delivery within 1-5 workdays)

Accession: 008652878

PDF Full Text: Submit

Submit PDF Full Text

No spam - Every submission is manually reviewed

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we have purchased)

Select a PDF file:

Other references

Rogers, Jf; Tariq, As; Ames, Gr, 1991: A fuel efficient kiln for Nile perch. Tropical science1(1): 83-94

Cham, S. A.; Seymour, M. K.; Hooper, D. J., 1983: Observations on a British hairworm, Parachordodes wolterstorffii (Nematomorpha: Gordiidae). Males of P. wolterstorffii from the New Forest, Hampshire, UK, were examined entire, in thick sections and in cuticle preparations by light (differential interference contrast) and scanning electron microscopy. Surface features, internal organizat...

Lapolla, Anthony, 1967: A double blind evaluation of chlorpromazine versus a combination of perphenazine and amitriptyline. Preliminary comparative clinical study of a new compound, Etrafon+[a combination of perphenazine and amitriptyline] a tranquilizer-antidepressant, with a widely used tranquilizer, chlorpromazine, was made in 50 male and female hospitalized schizop...

Landau, Ezekiel; Pugach, Jeff L.; Mclorie, Gordon A.; Merguerian, Paul A.; Bagli, Darius J.; Honey, John D.; Khoury, Antoine E.; Denstedt, John, 1999: Safety and efficacy of extracorporeal shock wave lithotripsy in infants. Journal of Urology 161(4 SUPPL ): 200, April

Nandi, BC., 1992: Sarcophagid fauna (Diptera: Sarcophagidae) of Karnataka, India. Hexapoda (Insecta Indica): 41: 65-82

Simmons M.L.; Robie D.M.; Jones J.B.; Serrano L.J., 1968: Effect of a inst filter cover on temperature and humidity in a inst mouse cage. Laboratory Animals (London) 2(2): 113-120

Sakamoto, Naoya; Martens, Jeffrey R.; Norris, Aaron; Tamkun, Michael M., 2002: PKC links cholesterol depletion to altered Kv21 function. Biophysical Journal 82(1 Part 2): 203a, January

Smit, Afj, 1972: Some fossil fish (acanthodian) National from the Sekondi series, lower Carboniferous of Ghana. Ghana J: 22.

Becker, V. O., 1977: The taxonomic position of the cecidosidae lepidoptera. A description of Cecidoses minutanus (Brethes) is given, based on larval, pupal and imaginal characters, and also of C. eremita Curtis, known only as imago. The genus Eucecidoses Brethes is synonymized with Cecidoses Curtis (new synonymy). The fam...

Anthony, W. B.; Harris, R. R.; Hoveland, C. S.; Mayton, E. L.; Boseck, J. K., 1967: Serala sericea as a grazing crop for beef cattle. In a 3-year field trial in Piedmont, sericea lespedeza cv. Serala gave results for cow-grazing days/ac and calf gains/ac similar to those obtained with Bermuda grass cv. Coastal receiving 100 lb N/ac.