Expression and release and the a and b subunits for human coagulation factor XIII in baby hamster kidney (BHK) cells
Kaetsu, H.; Hashiguchi, T.; Foster, D.; Ichinose, A.
Journal of Biochemistry (Tokyo) 119(5): 961-969
The a subunit of coagulation factor XIII lacks a hydrophobic signal sequence for secretion from cells, while the b subunit has a typical signal sequence. To determine whether the a subunit can be synthesized and released, expression vectors containing the cDNA for either subunit were transfected into baby hamster kidney (BHK) cells.