Section 9
Chapter 8,801

IRE-ABP (insulin response element-A binding protein) , an SRY-like protein, inhibits C/EBPalpha (CCAAT/enhancer-binding protein alpha) -stimulated expression of the sex-specific cytochrome P450 2C12 gene

Buggs, C.; Nasrin, N.; Mode, A.; Tollet, P.; Zhao, H.F.; Gustafsson, J.A.; Alexander-Bridges, M.

Molecular Endocrinology 12(9): 1294-1309


ISSN/ISBN: 0888-8809
PMID: 9731699
DOI: 10.1210/mend.12.9.0174
Accession: 008800324

Download citation:  

In primary hepatocytes, overexpression of an insulin response element-A binding protein (IRE-ABP), a member of the SRY family of high-mobility group (HMG) proteins, inhibits CCAAT/enhancer-binding protein alpha (C/EBPalpha)-mediated activation of the female-specific cytochrome P450 2C12 (CYP2C12) gene, but not the male-specific cytochrome P450 2C11 (CYP2C11) gene.

PDF emailed within 0-6 h: $19.90