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In vitro evaluation of iodine-125-labeled monoclonal antibody (MAb 425) in human high-grade glioma cells

In vitro evaluation of iodine-125-labeled monoclonal antibody (MAb 425) in human high-grade glioma cells

American Journal of Clinical Oncology 19(6): 601-608

Human high-grade glioma cell lines (A1207, U-87MG, U-373MG, and F39) with high levels of epidermal growth factor receptor (EGF-R) expression were incubated for 2-48 h with 1 mu-Ci/ml of the EGF-R-specific 125I-MAB 425 and measured for surface-bound, cytoplasmic, and nuclear radioactivity.

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Accession: 008837585

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PMID: 8931681

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