Increase in gonadotropin-releasing hormone (GnRH) levels in CSF after stimulation of the nervus terminalis in Atlantic stingray, Dasyatis sabina

Moeller, J.F.; Meredith, M.

Brain Research 806(1): 104-107


ISSN/ISBN: 0006-8993
PMID: 9739116
DOI: 10.1016/s0006-8993(98)00683-0
Accession: 008847204

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The nervus terminalis (NT) contains many cells immunoreactive to gonadotropin-releasing hormone (GnRH). The potential of the NT to release GnRH in vivo was investigated by stimulating the peripheral nerve trunk of Atlantic stingrays and collecting cerebrospinal fluid (CSF). The CSF samples from stimulated animals averaged about twice the levels of mGnRH-like peptide as those of unstimulated animals. These results demonstrate that nervus terminalis activity can effect in vivo GnRH levels in the brain.