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Liver function in patients with pulmonary emphysema due to severe alpha-1-antitrypsin deficiency (Pi ZZ)



Liver function in patients with pulmonary emphysema due to severe alpha-1-antitrypsin deficiency (Pi ZZ)



Digestion 57(3): 165-169



alpha-1-Antitrypsin deficiency predisposes to pulmonary emphysema, liver cirrhosis and hepatocellular carcinoma. Anecdotal evidence and a large autopsy study suggest that severe lung and liver disease rarely coexist in the same subject, but this has not been studied in patients. Therefore we investigated 27 patients with severe alpha-1-deficiency (Pi ZZ) and pulmonary emphysema for signs of liver disease and impaired hepatic function.

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Accession: 008962997

Download citation: RISBibTeXText

PMID: 8739089

DOI: 10.1159/000201331


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