MR imaging of postoperative change of dura mater of rabbits--effect of contrast enhancement of dura mater & correlation with pathological findings
Nihon Igaku Hoshasen Gakkai Zasshi. Nippon Acta Radiologica 53(1): 75-85
ISSN/ISBN: 0048-0428 PMID: 8441602 Accession: 008982215
To explain the mechanism of benign postoperative dural enhancement, the author made experimental model of rabbit's subdural hematoma and performed magnetic resonance (MR) imaging with gadolinium-diethylenetriaminepentaacetic acid (Gd-DTPA). On plain T1-weighted images, infused blood or red blood cells could not be detected immediately after surgery. On follow up plain T1-weighted images, the infused blood could be identified in only a case with 1 cc blood infusion. Marked dural enhancement could be seen immediately after surgery and continued three to fourteen days after 11 cc or 0.1 cc blood or 0.1 cc red blood cells infusion. To the contrary, no definite dural enhancement could be seen in the cases with plasma or saline infusion. Subdural red blood cells were required for dural enhancement immediately after surgery. Pathological findings revealed three types of reaction to infused blood: newly formed capillarization with fresh hemorrhage from the capillaries; subdural hematoma and no reaction. After vanishment of dural enhancement, pathological findings of the specimens were identical to that of normal dura. Dural enhancement may be induced by increased permeability of the dura associated with subdural hematoma and/or the extravasation of the contrast from newly formed capillaries.