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Mutants of the carotenoid biosynthetic pathway of Mucor circinelloides



Mutants of the carotenoid biosynthetic pathway of Mucor circinelloides



Experimental Mycology. : 186-190



We have isolated and characterized a number of mutants affected in the biosynthesis of beta-carotene in the fungus Mucor circinelloides. Mutants were obtained after mutagenesis with N-methyl-N'-nitro-N-nitrosoguanidine or ultraviolet radiation. Carotene analysis and determination of in vitro activity for synthesis of prenyl pyrophosphates confirm that we have obtained mutants for all enzymatic steps from farnesyl pyrophosphate to beta-carotene and regulatory mutants affecting total production of carotenes and light regulation.

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Accession: 009066544

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DOI: 10.1006/emyc.1995.1023


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