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Normal and neoplastic growth of mammary glands and circulating levels of prolactin and growth hormone in mouse whey acidic protein promoter/human growth hormone (mWAP/hGH) transgenic mice



Normal and neoplastic growth of mammary glands and circulating levels of prolactin and growth hormone in mouse whey acidic protein promoter/human growth hormone (mWAP/hGH) transgenic mice



Zoological Science (Tokyo) 10(6): 963-970



Female and male hybrids between SHN females with high mammary tumor potentials and a male transgenic mouse expressing a high human growth hormone (hGH) fusion gene under the control of mouse whey acidic protein as a promoter were divided into hGH (+) and hGH (-) groups according to serum hGH levels at 50 days of age (111 +- 16 ng/ml and 0.43+-0.05 ng/ml in females and 51+-4 ng/ml and 0.47+-0.05 ng/ml in males, respectively).

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