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Plant cell and tissue cultures as a source of protoberberine alkaloids



Plant cell and tissue cultures as a source of protoberberine alkaloids



Rastitel'nye Resursy 32(1-2): 134-151



The production of protoberberine alkaloids in cell and tissue cultures of Coptis japonica, Thalictrum minus, Berberis species as well the medical use these alkaloids have been reviewed. Several aspects of protoberberine accumulation such as biosynthesis and enzymology of the products, site of accumulation and transport of alkaloids, impact of environmental factors and new approaches enhancing of alkaloid production in cultured cells are discussed.

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Accession: 009201050

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