EurekaMag.com logo
+ Site Statistics
References:
53,214,146
Abstracts:
29,074,682
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Positive serology for Lyme borreliosis in patients with juvenile rheumatoid arthritis in a Lyme borreliosis endemic area: analysis by immunoblot






Journal of Rheumatology 20(4): 739-741

Positive serology for Lyme borreliosis in patients with juvenile rheumatoid arthritis in a Lyme borreliosis endemic area: analysis by immunoblot

Juvenile rheumatoid arthritis (JRA) and the arthritis of Lyme borreliosis in children can mimic each other. As false positive reactions are frequent in ELISA for Lyme borreliosis, they cannot be used reliably to make the distinction. Ninety-nine children diagnosed as having JRA at a children's hospital in an endemic area were evaluated by ELISA and immunoblot for antibodies to Borrelia burgdorferi. Sera from 9% were positive by ELISA, 5 of which showed bands on immunoblot. None met criteria for positive immunoblot. The antigenic basis of false positive ELISA was most frequently a reactivity to both 21 and 41 kDa. Analysis by immunoblot can help to definitively exclude Lyme borreliosis in children presenting with JRA in an endemic area.

(PDF 0-2 workdays service: $29.90)

Accession: 009215966

PMID: 8496876



Related references

Positive lyme disease ld serology in juvenile rheumatoid arthritis jra in a ld endemic area analysis by immunoblot ib. Arthritis & Rheumatism 34(9 SUPPL): S37, 1991

Lyme arthritis in Southern Norway--an endemic area for Lyme borreliosis. Bmc Infectious Diseases 14(): 185-185, 2015

Serum antibodies against Borrelia afzelii, Borrelia burgdorferi sensu stricto and the 41-kiloDalton flagellin in patients from a Lyme borreliosis endemic area: analysis by EIA and immunoblot. Apmis 104(12): 907-914, 1996

Use of immunoblot ib to distinguish juvenile rheumatoid arthritis jra from lyme disease ld in an endemic area. Pediatric Research 29(4 PART 2): 185A, 1991

The comparable frequency of juvenile lyme arthritis and juvenile rheumatoid arthritis in a lyme disease endemic area. Arthritis & Rheumatism 29(4 SUPPL): S67, 1986

OP0113Lyme arthritis in southern norway - an endemic area for lyme borreliosis. Annals of the Rheumatic Diseases 71(Suppl 3): 91.2-91, 2013

Early serologic diagnosis of Lyme borreliosis by VIDAS Lyme screen, Borrelia IgG and immunoblot. Abstracts of the General Meeting of the American Society for Microbiology 95(0): 37, 1995

European Union Concerted Action on Risk Assessment in Lyme Borreliosis: clinical case definitions for Lyme borreliosis. Wiener Klinische Wochenschrift 108(23): 741-747, 1996

What kind of clinical, epidemiological, and biological data is essential for the diagnosis of Lyme borreliosis? Dermatological and ophtalmological courses of Lyme borreliosis. Medecine et Maladies Infectieuses 37 Suppl 3: S175-S188, 2007

Relative frequency of Lyme borreliosis and of its clinical manifestations in Europe. European Community Concerted Action on Risk Assessment in Lyme Borreliosis. Infection 26(5): 298-300, 1998