Probes for narcotic receptor mediated phenomena 22. 1. Synthesis and characterization of optically pure (3H) (+) -4- ( (alpha-R) -alpha- ( (2S,5R) -4-propyl-2,5-dimethyl-1-piperazinyl) -3-methoxybenzyl) -N,N-diethylbenzamide, (3H) SNC 121, a novel high affinity and selective ligand for delta opioid receptors
Calderon, S., N.; Bertha, C., M.; Gutkind, J.S.; Xu, H.; Partilla, J., S.; Rothman, R., B.; Rice, K., C.
Journal of Labelled Compounds and Radiopharmaceuticals 38(9): 847-850
1996
ISSN/ISBN: 0362-4803
DOI: 10.1002/(sici)1099-1344(199609)38:9<847::aid-jlcr900>3.0.co;2-n
Accession: 009247315
The synthesis of unlabelled and labelled SNC 121, a selective nonpeptide ligand for the delta opioid receptor is reported. (3H)SNC 121 of specific activity of 26.8 Ci/mmol, was synthesized by catalytic tritiation of the optically pure precursor SNC 80.
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