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Prospective study of heart rate variability and mortality in chronic heart failure: results of the United Kingdom heart failure evaluation and assessment of risk trial (UK-heart)



Prospective study of heart rate variability and mortality in chronic heart failure: results of the United Kingdom heart failure evaluation and assessment of risk trial (UK-heart)



Circulation 98(15): 1510-1516



Background-Patients with chronic heart failure (CHF) have a continuing high mortality. Autonomic dysfunction may play an important role in the pathophysiology of cardiac death in CHF. UK-HEART examined the value of heart rate variability (HRV) measures as independent predictors of death in CHF. Methods and Results-In a prospective study powered for mortality, we recruited 433 outpatients 62 +- 9.6 years old with CHF (NYHA functional class I to III; mean ejection fraction, 0.41 +- 0.17).

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Accession: 009261764

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PMID: 9769304

DOI: 10.1161/01.cir.98.15.1510


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